Search Results - "Experimental gerontology"

Prevalence of sarcopenia as a comorbid disease: A systematic review and meta-analysis by Pacifico, Jacob, Geerlings, Milou A.J., Reijnierse, Esmee M., Phassouliotis, Christina, Lim, Wen Kwang, Maier, Andrea B.

“…Sarcopenia shares risk factors with various other age-related diseases. This meta-analysis aimed to determine the prevalence of sarcopenia as a comorbid…”
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Age and immunity: What is “immunosenescence”? by Pawelec, Graham

“…As is apparent from the many contributions to this Special Issue of the Journal, the impact of age on immunity is nefarious, with all manner of dysregulated…”
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Sex differences in frailty: A systematic review and meta-analysis by Gordon, E.H., Peel, N.M., Samanta, M., Theou, O., Howlett, S.E., Hubbard, R.E.

“…It is a well-described clinical phenomenon that females live longer than males, yet tend to experience greater levels of co-morbidity and disability. Females…”
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Aging, inflammation and the environment by Bektas, Arsun, Schurman, Shepherd H., Sen, Ranjan, Ferrucci, Luigi

“…The aging process is driven by interrelated mechanisms that lead to the emergence of characteristic phenotypes that include changes in body composition, energy…”
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The potential mechanism of postoperative cognitive dysfunction in older people by Lin, Xianyi, Chen, Yeru, Zhang, Piao, Chen, Gang, Zhou, Youfa, Yu, Xin

“…Postoperative cognitive dysfunction (POCD) is a common disorder following surgery, which seriously threatens the quality of patients' life, especially the…”
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Inflammation and sarcopenia: A focus on circulating inflammatory cytokines by Pan, Linyuan, Xie, Wenqing, Fu, Xin, Lu, Wenhao, Jin, Hongfu, Lai, Jieyu, Zhang, Aohan, Yu, Yongle, Li, Yusheng, Xiao, Wenfeng

“…Sarcopenia is an aged-related syndrome that is progressive and can be accelerated by other concomitant disease states. Sarcopenia, characterized by loss of…”
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Kynurenine pathway, NAD+ synthesis, and mitochondrial function: Targeting tryptophan metabolism to promote longevity and healthspan by Castro-Portuguez, Raul, Sutphin, George L.

“…Aging is characterized by a progressive decline in the normal physiological functions of an organism, ultimately leading to mortality. Nicotinamide adenine…”
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Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline by Tarantini, Stefano, Tran, Cam Ha T., Gordon, Grant R., Ungvari, Zoltan, Csiszar, Anna

“…The importance of (micro)vascular contributions to cognitive impairment and dementia (VCID) in aging cannot be overemphasized, and the pathogenesis and…”
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Exercise and probiotics attenuate the development of Alzheimer's disease in transgenic mice: Role of microbiome by Abraham, Dora, Feher, Janos, Scuderi, Gian Luca, Szabo, Dora, Dobolyi, Arpad, Cservenak, Melinda, Juhasz, Janos, Ligeti, Balazs, Pongor, Sandor, Gomez-Cabrera, Mari Carmen, Vina, Jose, Higuchi, Mitsuru, Suzuki, Katsuhiro, Boldogh, Istvan, Radak, Zsolt

“…It has been suggested that exercise training and probiotic supplementation could decelerate the progress of functional and biochemical deterioration in APP/PS1…”
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Covid-19 and the impact on the physical activity level of elderly people: A systematic review by Oliveira, Murilo Rezende, Sudati, Isabella Pessóta, Konzen, Vanessa De Mello, de Campos, Ana Carolina, Wibelinger, Lia Mara, Correa, Clisman, Miguel, Fabiano Moraes, Silva, Rebeca Nunes, Borghi-Silva, Audrey

“…Social isolation and lifestyle changes provoked by the COVID-19 pandemic have negatively affected the level of physical activity of the elderly people. To…”
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Interventions targeting loneliness and social isolation among the older people: An update systematic review by Poscia, Andrea, Stojanovic, Jovana, La Milia, Daniele Ignazio, Duplaga, Mariusz, Grysztar, Marcin, Moscato, Umberto, Onder, Graziano, Collamati, Agnese, Ricciardi, Walter, Magnavita, Nicola

“…This systematic review aims to summarize and update the current knowledge on the effectiveness of the existing interventions for alleviating loneliness and…”
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Role of D-galactose-induced brain aging and its potential used for therapeutic interventions by Shwe, Thazin, Pratchayasakul, Wasana, Chattipakorn, Nipon, Chattipakorn, Siriporn C.

“…Aging is a phenomenon that all living organisms inevitably face. Every year, 9.9million people, globally, suffer from dementia, an indicator of the aging…”
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The sit-to-stand muscle power test: An easy, inexpensive and portable procedure to assess muscle power in older people by Alcazar, Julian, Losa-Reyna, Jose, Rodriguez-Lopez, Carlos, Alfaro-Acha, Ana, Rodriguez-Mañas, Leocadio, Ara, Ignacio, García-García, Francisco J., Alegre, Luis M.

“…Skeletal muscle power has been demonstrated to be a stronger predictor of functional limitations than any other physical capability. However, no validated…”
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Aging and adipose tissue: potential interventions for diabetes and regenerative medicine by Palmer, Allyson K., Kirkland, James L.

“…Adipose tissue dysfunction occurs with aging and has systemic effects, including peripheral insulin resistance, ectopic lipid deposition, and inflammation…”
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A cross-sectional comparison of brain glucose and ketone metabolism in cognitively healthy older adults, mild cognitive impairment and early Alzheimer's disease by Croteau, E., Castellano, C.A., Fortier, M., Bocti, C., Fulop, T., Paquet, N., Cunnane, S.C.

“…Deteriorating brain glucose metabolism precedes the clinical onset of Alzheimer's disease (AD) and appears to contribute to its etiology. Ketone bodies, mainly…”
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Measuring gait speed to better identify prodromal dementia by Grande, Giulia, Triolo, Federico, Nuara, Arturo, Welmer, Anna-Karin, Fratiglioni, Laura, Vetrano, Davide L.

“…Slow gait speed has been shown to predict incident dementia and cognitive decline in older individuals. We aimed to summarize the evidence concerning the…”
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Digital behavior change interventions to promote physical activity and/or reduce sedentary behavior in older adults: A systematic review and meta-analysis by Stockwell, Stephanie, Schofield, Patricia, Fisher, Abi, Firth, Joseph, Jackson, Sarah E., Stubbs, Brendon, Smith, Lee

“…Physical activity and sedentary behavior are modifiable risk factors for non-communicable disease and healthy ageing, however the majority of older adults…”
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Aging, obesity, sarcopenia and the effect of diet and exercise intervention by Colleluori, Georgia, Villareal, Dennis T.

“…The number of adults 65 years and older is increasing worldwide and will represent the 20% of the population by 2030. Half of them will suffer from obesity…”
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Molecular mechanisms of UVB-induced senescence of dermal fibroblasts and its relevance for photoaging of the human skin by Cavinato, Maria, Jansen-Dürr, Pidder

“…Due to its ability to cross the epidermis and reach the upper dermis where it causes cumulative DNA damage and increased oxidative stress, UVB is considered…”
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T cells, aging and senescence by Pangrazzi, Luca, Weinberger, Birgit

“…The T cell compartment undergoes characteristic changes with age, which contribute to increased incidence and severity of infections and reduced immunogenicity…”
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