Search Results - "Experimental dermatology"

Cellular and molecular mechanisms in fibrosis by Dees, Clara, Chakraborty, Debomita, Distler, Jörg H. W.

“…The activation of fibroblasts is required for physiological tissue remodelling such as wound healing. However, when the regulatory mechanisms are disrupted and…”
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Hair follicle immune privilege and its collapse in alopecia areata by Bertolini, Marta, McElwee, Kevin, Gilhar, Amos, Bulfone‐Paus, Silvia, Paus, Ralf

“…Anagen stage hair follicles (HFs) exhibit “immune privilege (IP)” from the level of the bulge downwards to the bulb. Both passive and active IP mechanisms…”
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What causes hidradenitis suppurativa ?—15 years after by Zouboulis, Christos C., Benhadou, Farida, Byrd, Angel S., Chandran, Nisha S., Giamarellos‐Bourboulis, Evangelos J., Fabbrocini, Gabriella, Frew, John W., Fujita, Hideki, González‐López, Marcos A., Guillem, Philippe, Gulliver, Wayne P. F., Hamzavi, Iltefat, Hayran, Yildiz, Hórvath, Barbara, Hüe, Sophie, Hunger, Robert E., Ingram, John R., Jemec, Gregor B.E., Ju, Qiang, Kimball, Alexa B., Kirby, Joslyn S., Konstantinou, Maria P., Lowes, Michelle A., MacLeod, Amanda S., Martorell, Antonio, Marzano, Angelo V., Matusiak, Łukasz, Nassif, Aude, Nikiphorou, Elena, Nikolakis, Georgios, Nogueira da Costa, André, Okun, Martin M., Orenstein, Lauren A.V., Pascual, José Carlos, Paus, Ralf, Perin, Benjamin, Prens, Errol P., Röhn, Till A., Szegedi, Andrea, Szepietowski, Jacek C., Tzellos, Thrasyvoulos, Wang, Baoxi, van der Zee, Hessel H.

“…The 14 authors of the first review article on hidradenitis suppurativa (HS) pathogenesis published 2008 in EXPERIMENTAL DERMATOLOGY cumulating from the 1st…”
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Multimodal skin lesion classification using deep learning by Yap, Jordan, Yolland, William, Tschandl, Philipp

“…While convolutional neural networks (CNNs) have successfully been applied for skin lesion classification, previous studies have generally considered only a…”
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Atopic dermatitis in diverse racial and ethnic groups—Variations in epidemiology, genetics, clinical presentation and treatment by Kaufman, Bridget P., Guttman‐Yassky, Emma, Alexis, Andrew F.

“…Atopic dermatitis (AD) is a chronic inflammatory skin condition that affects diverse ethnic groups with varying prevalence. Despite a predominance of studies…”
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Antimicrobial peptides and wound healing: biological and therapeutic considerations by Mangoni, Maria Luisa, McDermott, Alison M., Zasloff, Michael

“…Repair of tissue wounds is a fundamental process to re‐establish tissue integrity and regular function. Importantly, infection is a major factor that hinders…”
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Skin pigmentation and its control: From ultraviolet radiation to stem cells by Yardman‐Frank, Joseph Michael, Fisher, David E.

“…In the light of substantial discoveries in epithelial and hair pigmentation pathophysiology, this review summarizes the current understanding of skin…”
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Vitamin D receptor(s): In the nucleus but also at membranes? by Zmijewski, Michal A., Carlberg, Carsten

“…The genomic actions of the vitamin D are mediated via its biologically most potent metabolite 1α,25‐dihydroxyvitamin D3 (1,25(OH)2D3) and the transcription…”
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The tension biology of wound healing by Harn, Hans I‐Chen, Ogawa, Rei, Hsu, Chao‐Kai, Hughes, Michael W., Tang, Ming‐Jer, Chuong, Cheng‐Ming

“…Following skin wounding, the healing outcome can be: regeneration, repair with normal scar tissue, repair with hypertrophic scar tissue or the formation of…”
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Systemic immune mechanisms in atopic dermatitis and psoriasis with implications for treatment by Guttman‐Yassky, Emma, Krueger, James G., Lebwohl, Mark G.

“…Atopic dermatitis (AD) and psoriasis are inflammatory skin diseases that negatively affect patients’ quality of life. Although distinctions exist between these…”
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Targeting the gut‐skin axis—Probiotics as new tools for skin disorder management? by Szántó, Magdolna, Dózsa, Anikó, Antal, Dóra, Szabó, Kornélia, Kemény, Lajos, Bai, Péter

“…The existence of a gut‐skin axis is supported by increasing evidence, but its translational potential is not widely recognized. Studies linked inflammatory…”
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The dynamic anatomy and patterning of skin by Wong, Richard, Geyer, Stefan, Weninger, Wolfgang, Guimberteau, Jean-Claude, Wong, Jason K.

“…The skin is often viewed as a static barrier that protects the body from the outside world. Emphasis on studying the skin's architecture and biomechanics in…”
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Efficacy and safety of ustekinumab treatment in adults with moderate‐to‐severe atopic dermatitis by Khattri, Saakshi, Brunner, Patrick M., Garcet, Sandra, Finney, Robert, Cohen, Steven R., Oliva, Margeaux, Dutt, Riana, Fuentes‐Duculan, Judilyn, Zheng, Xiuzhong, Li, Xuan, Bonifacio, Kathleen M., Kunjravia, Norma, Coats, Israel, Cueto, Inna, Gilleaudeau, Patricia, Sullivan‐Whalen, Mary, Suárez‐Fariñas, Mayte, Krueger, James G., Guttman‐Yassky, Emma

“…Atopic dermatitis (AD) is the most common inflammatory skin disease, but treatment options for moderate‐to‐severe disease are limited. Ustekinumab is an…”
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The Akkermansia muciniphila is a gut microbiota signature in psoriasis by Tan, LiRong, Zhao, Shuang, Zhu, Wu, Wu, Lisha, Li, Jie, Shen, MinXue, Lei, Li, Chen, Xiang, Peng, Cong

“…Psoriasis is an immune‐mediated chronic inflammatory skin disease. Although its pathogenesis is not fully understood, Th17 cells and the cytokines they…”
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A cold plasma jet accelerates wound healing in a murine model of full‐thickness skin wounds by Schmidt, Anke, Bekeschus, Sander, Wende, Kristian, Vollmar, Brigitte, Woedtke, Thomas

“…Cold plasma has been successfully applied in several fields of medicine that require, for example, pathogen inactivation, implant functionalization or…”
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Hypertrophic scars and keloids: Overview of the evidence and practical guide for differentiating between these abnormal scars by Limandjaja, Grace C., Niessen, Frank B., Scheper, Rik J., Gibbs, Susan

“…Although hypertrophic scars and keloids both generate excessive scar tissue, keloids are characterized by their extensive growth beyond the borders of the…”
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Keloid disorder: Fibroblast differentiation and gene expression profile in fibrotic skin diseases by Macarak, Edward J., Wermuth, Peter J., Rosenbloom, Joel, Uitto, Jouni

“…Keloid disorder, a group of fibroproliferative skin diseases, is characterized by unremitting accumulation of the extracellular matrix (ECM) of connective…”
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Wound healing applications of creams and “smart” hydrogels by Stan, Diana, Tanase, Cristiana, Avram, Marioara, Apetrei, Roxana, Mincu, Nicolae‐Bogdan, Mateescu, Andreea Lorena, Stan, Dana

“…Although superficial wounds are often easy to treat for healthy individuals, there are some more severe types of wounds (burns, ulcers, diabetic wounds, etc.)…”
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Understanding the immune landscape in atopic dermatitis: The era of biologics and emerging therapeutic approaches by Moyle, Matthew, Cevikbas, Ferda, Harden, Jamie L., Guttman‐Yassky, Emma

“…Atopic dermatitis (AD) is a chronic, systemic, inflammatory disease that affects the skin and is characterized by persistent itch and marked redness. AD is…”
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Bioprinting of biomimetic skin containing melanocytes by Min, Daejin, Lee, Wonhye, Bae, Il‐Hong, Lee, Tae Ryong, Croce, Phillip, Yoo, Seung‐Schik

“…This study reports a three‐dimensional (3D) bioprinting technique that is capable of producing a full‐thickness skin model containing pigmentation. Multiple…”
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