Search Results - "Exconde, Patrick"

Inflammatory caspase substrate specificities by Exconde, Patrick M, Bourne, Christopher M, Kulkarni, Madhura, Discher, Bohdana M, Taabazuing, Cornelius Y

“…Caspases are a family of cysteine proteases that act as molecular scissors to cleave substrates and regulate biological processes such as programmed cell death…”
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The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases by Exconde, Patrick M., Hernandez-Chavez, Claudia, Bourne, Christopher M., Richards, Rachel M., Bray, Mark B., Lopez, Jan L., Srivastava, Tamanna, Egan, Marisa S., Zhang, Jenna, Yoo, William, Shin, Sunny, Discher, Bohdana M., Taabazuing, Cornelius Y.

“…Inflammasomes are multiprotein signaling complexes that activate the innate immune system. Canonical inflammasomes recruit and activate caspase-1, which then…”
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Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS by Akuma, Daniel C, Wodzanowski, Kimberly A, Schwartz Wertman, Ronit, Exconde, Patrick M, Vázquez Marrero, Víctor R, Odunze, Chukwuma E, Grubaugh, Daniel, Shin, Sunny, Taabazuing, Cornelius, Brodsky, Igor E

“…Inflammatory caspases are cysteine protease zymogens whose activation following infection or cellular damage occurs within supramolecular organizing centers…”
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Abstract 1386: Evolutionary Advantage to Protein Splicing in an Extreme Halophile by Barbesino, Beatrice, Mills, Kenneth, Exconde, Patrick, Janton, C.J.

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Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS by Wodzanowski, Kimberly, Akuma, Daniel, Schwartz Wertman, Ronit, Exconde, Patrick, Vazquez Marrero, Victor, Odunze, Chukwuma, Grubaugh, Daniel, Shin, Sunny, Taabazuing, Cornelius, Brodsky, Igor

“…Inflammatory caspases are cysteine protease zymogens whose activation following infection or cellular damage occurs within supramolecular organizing centers…”
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The relationship of structural stability to temperature‐dependent activity in a family of thermophilic inteins by Exconde, Patrick M., Gomez, Alvin V., Mills, Kenneth V.

“…Protein splicing is a post‐translational process by which a self‐catalyzing intervening sequence called an intein removes itself from a precursor protein and…”
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Fitness Cost of Two Inteins in Halobacterium salinarum by Exconde, Patrick M., Janton, Christopher J., Makkay, Andrea M., Papke, R. Thane, Gomez, Alvin V., Mills, Kenneth V.

“…Halobacterium salinarum is from the domain Archaea and an obligate inhabitant of extremely saline conditions, including saturated brines. Its PolII and Cdc21a…”
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