Search Results - "Excoffon, Katherine J D A"

Isoform-specific regulation and localization of the coxsackie and adenovirus receptor in human airway epithelia by Excoffon, Katherine J D A, Gansemer, Nicholas D, Mobily, Matthew E, Karp, Philip H, Parekh, Kalpaj R, Zabner, Joseph

“…Adenovirus is an important respiratory pathogen. Adenovirus fiber from most serotypes co-opts the Coxsackie-Adenovirus Receptor (CAR) to bind and enter cells…”
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A novel host defense system of airways is defective in cystic fibrosis by Moskwa, Patryk, Lorentzen, Daniel, Excoffon, Katherine J D A, Zabner, Joseph, McCray, Jr, Paul B, Nauseef, William M, Dupuy, Corinne, Bánfi, Botond

“…The respiratory tract is constantly exposed to airborne microorganisms. Nevertheless, normal airways remain sterile without recruiting phagocytes. This innate…”
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Reovirus Preferentially Infects the Basolateral Surface and Is Released from the Apical Surface of Polarized Human Respiratory Epithelial Cells by Excoffon, Katherine J. D. A., Guglielmi, Kristen M., Wetzel, J. Denise, Gansemer, Nicholas D., Campbell, Jacquelyn A., Dermody, Terence S., Zabner, Joseph

“…Mammalian reoviruses infect respiratory and gastrointestinal epithelia and cause disease in neonates. Junctional adhesion molecule–A (JAM-A) is a…”
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Adenovirus Co-Opts Neutrophilic Inflammation to Enhance Transduction of Epithelial Cells by Readler, James M, Burke, Meghan R, Sharma, Priyanka, Excoffon, Katherine J D A, Kolawole, Abimbola O

“…Human adenoviruses (HAdV) cause a variety of infections in human hosts, from self-limited upper respiratory tract infections in otherwise healthy people to…”
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The Coxsackievirus and Adenovirus Receptor Has a Short Half-Life in Epithelial Cells by Kotha Lakshmi Narayan, Poornima, Readler, James M, Alghamri, Mahmoud S, Brockman, Trisha L, Yan, Ran, Sharma, Priyanka, Snitsarev, Vladislav, Excoffon, Katherine J D A, Kolawole, Abimbola O

“…The coxsackievirus and adenovirus receptor (CAR) is an essential cellular protein that is involved in cell adhesion, cell signaling, and viral infection. The…”
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Sidestream smoke exposure increases the susceptibility of airway epithelia to adenoviral infection by Sharma, Priyanka, Kolawole, Abimbola O, Core, Susan B, Kajon, Adriana E, Excoffon, Katherine J D A

“…Although significant epidemiological evidence indicates that cigarette smoke exposure increases the incidence and severity of viral infection, the molecular…”
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Enhanced Sialic Acid-Dependent Endocytosis Explains the Increased Efficiency of Infection of Airway Epithelia by a Novel Adeno-Associated Virus by DICKEY, David D, EXCOFFON, Katherine J. D. A, KOERBER, James T, BERGEN, Jamie, STEINES, Benjamin, KLESNEY-TAIT, Julia, SCHAFFER, David V, ZABNER, Joseph

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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MAGI-1 PDZ2 Domain Blockade Averts Adenovirus Infection via Enhanced Proteolysis of the Apical Coxsackievirus and Adenovirus Receptor by Alghamri, Mahmoud S, Sharma, Priyanka, Williamson, Timothy L, Readler, James M, Yan, Ran, Rider, Jr, S Dean, Hostetler, Heather A, Cool, David R, Kolawole, Abimbola O, Excoffon, Katherine J D A

“…Adenoviruses (AdVs) are etiological agents of gastrointestinal, heart, eye, and respiratory tract infections that can be lethal for immunosuppressed people…”
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Paracellular Permeability Restricts Airway Epithelial Responses to Selectively Allow Activation by Mediators at the Basolateral Surface by Humlicek, Alicia L, Manzel, Lori J, Chin, Cecilia L, Shi, Lei, Excoffon, Katherine J. D. A, Winter, Michael C, Shasby, D. Michael, Look, Dwight C

“…Respiratory pathogens and toxins often assault the lung from the airway lumen. Airway epithelia may initiate and amplify inflammation in response to these…”
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Adenovirus entry from the apical surface of polarized epithelia is facilitated by the host innate immune response by Kotha, Poornima L N, Sharma, Priyanka, Kolawole, Abimbola O, Yan, Ran, Alghamri, Mahmoud S, Brockman, Trisha L, Gomez-Cambronero, Julian, Excoffon, Katherine J D A

“…Prevention of viral-induced respiratory disease begins with an understanding of the factors that increase or decrease susceptibility to viral infection. The…”
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Directed evolution of adeno-associated virus to an infectious respiratory virus by Excoffon, Katherine J.D.A, Koerber, James T, Dickey, David D, Murtha, Matthew, Keshavjee, Shaf, Kaspar, Brian K, Zabner, Joseph, Schaffer, David V

“…Respiratory viruses evolve to maintain infectivity levels that permit spread yet prevent host and virus extinction, resulting in surprisingly low infection…”
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The Role of the Extracellular Domain in the Biology of the Coxsackievirus and Adenovirus Receptor by Excoffon, Katherine J. D. A, Traver, Geri L, Zabner, Joseph

“…The Coxsackievirus B and Adenovirus Receptor (CAR) plays a dual role as a homotypic junctional adhesion protein and as a viral receptor. CAR is a transmembrane…”
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A Novel Host Defense System of Airways Is Defective in Cystic Fibrosis by Moskwa, Patryk, Lorentzen, Daniel, Excoffon, Katherine J. D. A, Zabner, Joseph, McCray, Paul B., Jr, Nauseef, William M, Dupuy, Corinne, Banfi, Botond

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The coxsackievirus and adenovirus receptor: virological and biological beauty by Excoffon, Katherine J. D. A.

“…The coxsackievirus and adenovirus receptor (CAR) is an essential multifunctional cellular protein that is only beginning to be understood. CAR serves as a…”
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Poliovirus Receptor: More than a simple viral receptor by Bowers, Jonathan R., Readler, James M., Sharma, Priyanka, Excoffon, Katherine J.D.A.

“…•Human PVR (CD155) is both a viral receptor and immunomodulatory protein.•PVR function depends on expression of alternative protein isoforms.•Poliovirus is a…”
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The magic of MAGI-1: A scaffolding protein with multi signalosomes and functional plasticity by Excoffon, Katherine J D A, Avila, Christina L, Alghamri, Mahmoud S, Kolawole, Abimbola O

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SP-101, A Novel Adeno-Associated Virus Gene Therapy for the Treatment of Cystic Fibrosis, Mediates Functional Correction of Primary Human Airway Epithelia From Donors with Cystic Fibrosis by Excoffon, Katherine J D A, Lin, Shen, Narayan, Poornima Kotha Lakshmi, Sitaraman, Sneha, Jimah, Awal M, Fallon, Tyler T, James, Melane L, Glatfelter, Matthew R, Limberis, Maria P, Smith, Mark D, Guffanti, Guia, Kolbeck, Roland

“…Cystic fibrosis (CF) is caused by mutations in the gene encoding the CF transmembrane conductance regulator (CFTR) protein. Although CF affects multiple…”
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Isoform specific editing of the coxsackievirus and adenovirus receptor by Readler, James M., AlKahlout, Amal S., Sharma, Priyanka, Excoffon, Katherine J.D.A.

“…The Coxsackievirus and adenovirus receptor (CAR) is both a viral receptor and cell adhesion protein. CAR has two transmembrane isoforms that localize…”
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Spironolactone Depletes the XPB Protein and Inhibits DNA Damage Responses in UVB-Irradiated Human Skin by Kemp, Michael G., Krishnamurthy, Smita, Kent, Michael N., Schumacher, David L., Sharma, Priyanka, Excoffon, Katherine J.D.A., Travers, Jeffrey B.

“…UVB wavelengths of light induce the formation of photoproducts in genomic DNA that are potentially mutagenic and detrimental to epidermal cell function. The…”
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The magic of MAGI‐1: A scaffolding protein with multi signalosomes and functional plasticity by Excoffon, Katherine J. D. A., Avila, Christina L., Alghamri, Mahmoud S., Kolawole, Abimbola O.

“…MAGI‐1 is a critical cellular scaffolding protein with over 110 different cellular and microbial protein interactors. Since the discovery of MAGI‐1 in 1997,…”
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