Search Results - "Ewens, W J"

The TDT and other family-based tests for linkage disequilibrium and association by SPIELMAN, R. S, EWENS, W. J

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A Sibship Test for Linkage in the Presence of Association: The Sib Transmission/Disequilibrium Test by Spielman, Richard S., Ewens, Warren J.

“…Linkage analysis with genetic markers has been successful in the localization of genes for many monogenic human diseases. In studies of complex diseases,…”
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The transmission/disequilibrium test : history, subdivision, and admixture by EWENS, W. J, SPIELMAN, R. S

“…Disease association with a genetic marker is often taken as a preliminary indication of linkage with disease susceptibility. However, population subdivision…”
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Transmission test for linkage disequilibrium : the insulin gene region and insulin-dependent diabetes mellitus (IDDM) by SPIELMAN, R. S, MCGINNIS, R. E, EWENS, W. J

“…A population association has consistently been observed between insulin-dependent diabetes mellitus (IDDM) and the "class 1" alleles of the region of…”
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Simulating the component counts of combinatorial structures by Arratia, Richard, Barbour, A.D., Ewens, W.J., Tavaré, Simon

“…This article describes and compares methods for simulating the component counts of random logarithmic combinatorial structures such as permutations and…”
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An interpretation and proof of the Fundamental Theorem of Natural Selection by Ewens, W J

“…Fisher's "Fundamental Theorem of Natural Selection" has long caused controversy in population genetics theory. Viewed as a statement about the increase, or…”
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An optimizing principle of natural selection in evolutionary population genetics by Ewens, W J

“…This paper brings together two themes in evolutionary population genetics theory. The first concerns Fisher's Fundamental Theorem of Natural Selection: a…”
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Linkage-disequilibrium mapping without genotyping by Cheung, Vivian G, Gregg, Jeffrey P, Gogolin-Ewens, Kathryn J, Bandong, Jonathan, Stanley, Charles A, Baker, Lester, Higgins, Michael J, Nowak, Norma J, Shows, Thomas B, Ewens, Warren J, Nelson, Stanley F, Spielman, Richard S

“…Genomic mismatch scanning (GMS) is a technique that enriches for regions of identity by descent (IBD) between two individuals without the need for genotyping…”
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Heterozygosity Mapping of Partially Congenic Lines: Mapping of a Semidominant Neurological Mutation, Wheels (Whl), on Mouse Chromosome 4 by Nolan, P. M, Sollars, P. J, Bohne, B. A, Ewens, W. J, Pickard, G. E, Bucan, M

“…We identified a semidominant, chemically induced, mouse mutation with a complex array of abnormal behaviors including bidirectional circling and hyperactivity,…”
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Significance testing for direct identity-by-descent mapping by GRANT, G. R., MANDUCHI, E., CHEUNG, V. G., EWENS, W. J.

“…Direct identity-by-descent mapping is a technique for narrowing down the location of the gene or genes responsible for a given genetic disease to small…”
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The transmission/disequilibrium test detects cosegregation and linkage by Spielman, R S, McGinnis, R E, Ewens, W J

“…In a recent paper we described a test of linkage between a disease and a marker locus, to be used when when there is a population association between the two…”
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Markov-recapture population estimates: a tool for improving interpretation of trapping experiments by Wileyto, E.P, Ewens, W.J, Mullen, M.A

“…A method of wildlife population estimation is described in which individuals are marked by a self-marking bait station. The estimate is based on the assumption…”
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Genome mapping with anchored clones: theoretical aspects by Ewens, W J, Bell, C J, Donnelly, P J, Dunn, P, Matallana, E, Ecker, J R

“…As part of our effort to construct a physical map of the genome of Arabidopsis thaliana we have made a mathematical analysis of our experimental approach of…”
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Statistical analysis of in situ hybridization data: derivation and use of the zmax test by Ewens, W J, Griffiths, R C, Ethier, S N, Wilcox, S A, Graves, J A

“…There are many situations in which grain distributions resulting from in situ hybridization of radioactively labeled probes to unique genes should be subjected…”
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A resolution of the ascertainment sampling problem. I. Theory by Ewens, W J, Shute, N C

“…We consider the "ascertainment problem" arising when families are sampled by a nonrandom sampling process and, for the purpose of estimating genetic…”
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A resolution of the ascertainment sampling problem. III: Pedigrees by SHUTE, N. C. E, EWENS, W. J

“…When nuclear families are sampled by an ascertainment procedure whose properties are not known, biased estimates of genetic parameters will arise if an…”
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A resolution of the ascertainment sampling problem. II: Generalizations and numerical results by SHUTE, N. C. E, EWENS, W. J

“…The ascertainment problem arises when families are sampled by a nonrandom process and some assumption about this sampling process must be made in order to…”
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Multifactorial analysis of family data ascertained through truncation : a comparative evaluation of two methods of statistical inference by RAO, D. C, WETTE, R, EWENS, W. J

“…When family data are ascertained through single selection based on truncation, a prevailing method of analysis is to condition the likelihood function on the…”
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Estimation of Genetic Variation at the DNA Level from Restriction Endonuclease Data by Ewens, W. J., Spielman, Richard S., Harris, Harry

“…We consider the estimation of the genetic variation in a natural population when the data are obtained by the use of restriction endonucleases. Under the…”
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Is Knowing the Age-Order of Alleles in a Sample Useful in Testing for Selective Neutrality? by Tavare, S, Ewens, W. J, Joyce, P

“…The most powerful, and most frequently used, test of selective neutrality, based on data consisting of observed allelic frequencies in a sample of genes at…”
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