Search Results - "Eweas, Ahmad F"
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Molecular Docking Reveals Ivermectin and Remdesivir as Potential Repurposed Drugs Against SARS-CoV-2
Published in Frontiers in microbiology (25-01-2021)“…SARS-CoV-2 is a newly emerged coronavirus that causes a respiratory disease with variable severity and fatal consequences. It was first reported in Wuhan and…”
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Virtual Screening of Repurposed Drugs as Potential Spike Protein Inhibitors of Different SARS-CoV-2 Variants: Molecular Docking Study
Published in Current issues in molecular biology (04-07-2022)“…Like most of the RNA viruses, SARS-CoV-2 continuously mutates. Although many mutations have an insignificant impact on the virus properties, mutations in the…”
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Targeting thioredoxin glutathione reductase as a potential antischistosomal drug target
Published in Molecular and biochemical parasitology (01-10-2018)“…Electron transpiration process in TGR. [Display omitted] Schistosomiasis represents a world health major problem affecting more than 206 million people…”
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A Greener Approach Synthesis and Docking Studies of Perimidine Derivatives as Potential Anticancer Agents
Published in Journal of heterocyclic chemistry (01-02-2018)“…Microwave solvent‐free technique was employed to the synthesis of series of 2‐(1H‐perimidin‐2(3H)‐ylidene) derivatives,…”
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Synthesis, antibacterial evaluation, and docking studies of azaisoflavone analogues generated by palladium-catalyzed cross coupling
Published in Monatshefte für Chemie (01-10-2018)“…Palladium-catalyzed, cross-coupling reaction of N -methyl-3-iodo-4-quinolone with boronic acids or N -methyliminodiacetic acid boronates to obtain…”
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Synthesis, in vitro antioxidant, anticancer activity and molecular docking of new thiazole derivatives
Published in Results in Chemistry (01-01-2024)“…[Display omitted] Nitrogen and sulfur-containing heterocyclic aromatic derivatives play an enormous and important role in the field of medicine and in…”
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In vivo schistosomicidal activity of three novels 8-hydroxyquinoline derivatives against adult and immature worms of Schistosoma mansoni
Published in Parasitology research (1987) (01-09-2013)“…Schistosomiasis control is widely dependent on a single drug, praziquantel (PZQ). The potential for development of resistance to PZQ has justified the search…”
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Design, synthesis, anti-schistosomal activity and molecular docking of novel 8-hydroxyquinoline-5-sufonyl 1,4-diazepine derivatives
Published in Bioorganic chemistry (01-02-2013)“…[Display omitted] ► Novel 8-hydroxyquinoline-5-sufonyl 1,4-diazepine derivatives were synthesized. ► Their in vitro anti-schistosomal activity were reported. ►…”
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In-silico structural analysis of the influenza A subtype H7N9 neuraminidase and molecular docking with different neuraminidase inhibitors
Published in Virusdisease (01-06-2015)“…Human infection with H7 influenza subtypes usually resulted in mild disease with a rare mortalities, however, human infection with the avian low pathogenic…”
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Design, Synthesis, and Molecular Docking of Novel Pyrrolooxazepinediol Derivatives with Anti-Influenza Neuraminidase Activity
Published in Archiv der Pharmazie (Weinheim) (01-11-2015)“…A series of novel pyrrolo[2,1‐b][1,3]oxazepine‐8,9‐diol derivatives 12–15 were synthesized starting from l‐tartaric acid, which was transformed into anhydride…”
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SYNTHESIS, BIOLOGICAL EVALUATION AND MOLECULAR DOCKING STUDIES OF AROMATIC SULFONAMIDE DERIVATIVES AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS
Published in Acta Poloniae pharmaceutica (01-09-2016)“…In this study, [4-(N-substituted sulfamoyl)phenyl]carbonohydrazonoy dicyanides 3a-c were synthesized and condensed with various hydrazine hydrate derivatives…”
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Synthesis, molecular docking of novel 1,8-naphthyridine derivatives and their cytotoxic activity against HepG2 cell lines
Published in Medicinal chemistry research (2014)“…A series of novel 2,7-dimethyl-1,8-naphthyridine derivatives substituted with Mannich bases 2a – d , N -β-glycosides 6a – e , 7a – e , Schiff’s bases 8a – c ,…”
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Synthesis, anti-microbial evaluation, and molecular modeling of new pyrazolo[3,4-d]pyrimidine derivatives
Published in Medicinal chemistry research (01-11-2012)“…Synthesis of some new pyrazolo[3,4- d ]pyrimidine derivatives using readily available starting materials are described. A one-pot multi component…”
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Design, synthesis, anti-inflammatory, analgesic screening, and molecular docking of some novel 2-pyridyl (3H)-quinazolin-4-one derivatives
Published in Medicinal chemistry research (01-02-2013)“…A novel series of 6-bromo-2-(4-pyridyl)-quinazolin-4(3 H )-ones were synthesized by reacting 5-bromo anthranilic acid with isonictinoly chloride in the…”
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Synthetic studies directed towards soraphen A(1alpha)
Published 01-01-2004“…The C11–C17 segment of soraphen A1 with inverted stereochemistry at C17 as required for ring closure was prepared from the optically active dieneoate 136 in 8…”
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Dissertation