Search Results - "Ewbank, Jonathan J"

Activation of a G protein–coupled receptor by its endogenous ligand triggers the innate immune response of Caenorhabditis elegans by Zugasti, Olivier, Bose, Neelanjan, Squiban, Barbara, Belougne, Jérôme, Kurz, C Léopold, Schroeder, Frank C, Pujol, Nathalie, Ewbank, Jonathan J

“…The sensors of damage and danger in the nematode epidermis are unclear. Ewbank and colleagues show that the G protein–coupled receptor DCAR-1 detects…”
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A comprehensive analysis of gene expression changes provoked by bacterial and fungal infection in C. elegans by Engelmann, Ilka, Griffon, Aurélien, Tichit, Laurent, Montañana-Sanchis, Frédéric, Wang, Guilin, Reinke, Valerie, Waterston, Robert H, Hillier, LaDeana W, Ewbank, Jonathan J

“…While Caenorhabditis elegans specifically responds to infection by the up-regulation of certain genes, distinct pathogens trigger the expression of a common…”
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C. elegans: model host and tool for antimicrobial drug discovery by Ewbank, Jonathan J, Zugasti, Olivier

“…For almost four decades, the nematode Caenorhabditis elegans has been of great value in many fields of biological research. It is now used extensively in…”
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Detection and avoidance of a natural product from the pathogenic bacterium Serratia marcescens by Caenorhabditis elegans by Pradel, Elizabeth, Zhang, Yun, Pujol, Nathalie, Matsuyama, Tohey, Bargmann, Cornelia I, Ewbank, Jonathan J

“…The nematode Caenorhabditis elegans is present in soils and composts, where it can encounter a variety of microorganisms. Some bacteria in these rich…”
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Evolutionary plasticity in the innate immune function of Akirin by Polanowska, Jolanta, Chen, Jia-Xuan, Soulé, Julien, Omi, Shizue, Belougne, Jerome, Taffoni, Clara, Pujol, Nathalie, Selbach, Matthias, Zugasti, Olivier, Ewbank, Jonathan J

“…Eukaryotic gene expression requires the coordinated action of transcription factors, chromatin remodelling complexes and RNA polymerase. The conserved nuclear…”
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Genome evolution and plasticity of Serratia marcescens, an important multidrug-resistant nosocomial pathogen by Iguchi, Atsushi, Nagaya, Yutaka, Pradel, Elizabeth, Ooka, Tadasuke, Ogura, Yoshitoshi, Katsura, Keisuke, Kurokawa, Ken, Oshima, Kenshiro, Hattori, Masahira, Parkhill, Julian, Sebaihia, Mohamed, Coulthurst, Sarah J, Gotoh, Naomasa, Thomson, Nicholas R, Ewbank, Jonathan J, Hayashi, Tetsuya

“…Serratia marcescens is an important nosocomial pathogen that can cause an array of infections, most notably of the urinary tract and bloodstream. Naturally, it…”
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Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences by Zhang, Xing, Harding, Benjamin W, Aggad, Dina, Courtine, Damien, Chen, Jia-Xuan, Pujol, Nathalie, Ewbank, Jonathan J

“…Animals and plants need to defend themselves from pathogen attack. Their defences drive innovation in virulence mechanisms, leading to never-ending cycles of…”
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Distinct Innate Immune Responses to Infection and Wounding in the C. elegans Epidermis by Pujol, Nathalie, Cypowyj, Sophie, Ziegler, Katja, Millet, Anne, Astrain, Aline, Goncharov, Alexandr, Jin, Yishi, Chisholm, Andrew D., Ewbank, Jonathan J.

“…In many animals, the epidermis is in permanent contact with the environment and represents a first line of defense against pathogens and injury. Infection of…”
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A model of bacterial intestinal infections in Drosophila melanogaster by Nehme, Nadine T, Liégeois, Samuel, Kele, Beatrix, Giammarinaro, Philippe, Pradel, Elizabeth, Hoffmann, Jules A, Ewbank, Jonathan J, Ferrandon, Dominique

“…Serratia marcescens is an entomopathogenic bacterium that opportunistically infects a wide range of hosts, including humans. In a model of septic injury, if…”
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Unusual regulation of a STAT protein by an SLC6 family transporter in C. elegans epidermal innate immunity by Dierking, Katja, Polanowska, Jolanta, Omi, Shizue, Engelmann, Ilka, Gut, Marta, Lembo, Frederique, Ewbank, Jonathan J, Pujol, Nathalie

“…The cuticle and epidermis of Caenorhabditis elegans provide the first line of defense against invading pathogens. Upon invasion by the fungal pathogen…”
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De novo assembly of the complex genome of Nippostrongylus brasiliensis using MinION long reads by Eccles, David, Chandler, Jodie, Camberis, Mali, Henrissat, Bernard, Koren, Sergey, Le Gros, Graham, Ewbank, Jonathan J

“…Eukaryotic genome assembly remains a challenge in part due to the prevalence of complex DNA repeats. This is a particularly acute problem for holocentric…”
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Microtubule plus-end dynamics link wound repair to the innate immune response by Taffoni, Clara, Omi, Shizue, Huber, Caroline, Mailfert, Sébastien, Fallet, Mathieu, Rupprecht, Jean-François, Ewbank, Jonathan J, Pujol, Nathalie

“…The skin protects animals from infection and physical damage. In wounding the epidermis triggers an immune reaction and a repair response, but it is not clear…”
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Comparative Genomic Analysis of Drechmeria coniospora Reveals Core and Specific Genetic Requirements for Fungal Endoparasitism of Nematodes by Lebrigand, Kevin, He, Le D, Thakur, Nishant, Arguel, Marie-Jeanne, Polanowska, Jolanta, Henrissat, Bernard, Record, Eric, Magdelenat, Ghislaine, Barbe, Valérie, Raffaele, Sylvain, Barbry, Pascal, Ewbank, Jonathan J

“…Drechmeria coniospora is an obligate fungal pathogen that infects nematodes via the adhesion of specialized spores to the host cuticle. D. coniospora is…”
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Independent Synchronized Control and Visualization of Interactions between Living Cells and Organisms by Rouger, Vincent, Bordet, Guillaume, Couillault, Carole, Monneret, Serge, Mailfert, Sébastien, Ewbank, Jonathan J., Pujol, Nathalie, Marguet, Didier

“…To investigate the early stages of cell-cell interactions occurring between living biological samples, imaging methods with appropriate spatiotemporal…”
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SMF-1, SMF-2 and SMF-3 DMT1 orthologues regulate and are regulated differentially by manganese levels in C. elegans by Au, Catherine, Benedetto, Alexandre, Anderson, Joel, Labrousse, Arnaud, Erikson, Keith, Ewbank, Jonathan J, Aschner, Michael

“…Manganese (Mn) is an essential metal that can exert toxic effects at high concentrations, eventually leading to Parkinsonism. A major transporter of Mn in…”
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TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM by Sabatier, Laurence, Guichou, Jean-François, Kohara, Yuji, Couillault, Carole, Ewbank, Jonathan J, Reboul, Jérôme, Pujol, Nathalie

“…Both plants and animals respond to infection by synthesizing compounds that directly inhibit or kill invading pathogens. We report here the identification of…”
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Increased pathogenicity of the nematophagous fungus Drechmeria coniospora following long-term laboratory culture by Courtine, Damien, Zhang, Xing, Ewbank, Jonathan J

“…Domestication provides a window into adaptive change. Over the course of 2 decades of laboratory culture, a strain of the nematode-specific fungus became more…”
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A genome-wide collection of Mos1 transposon insertion mutants for the C. elegans research community by Vallin, Elodie, Gallagher, Joseph, Granger, Laure, Martin, Edwige, Belougne, Jérôme, Maurizio, Julien, Duverger, Yohann, Scaglione, Sarah, Borrel, Caroline, Cortier, Elisabeth, Abouzid, Karima, Carre-Pierrat, Maité, Gieseler, Kathrin, Ségalat, Laurent, Kuwabara, Patricia E, Ewbank, Jonathan J

“…Methods that use homologous recombination to engineer the genome of C. elegans commonly use strains carrying specific insertions of the heterologous transposon…”
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Modulatory upregulation of an insulin peptide gene by different pathogens in C. elegans by Lee, Song-Hua, Omi, Shizue, Thakur, Nishant, Taffoni, Clara, Belougne, Jérôme, Engelmann, Ilka, Ewbank, Jonathan J., Pujol, Nathalie

“…When an animal is infected, its innate immune response needs to be tightly regulated across tissues and coordinated with other aspects of organismal…”
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Caenorhabditis elegans semi-automated liquid screen reveals a specialized role for the chemotaxis gene cheB2 in Pseudomonas aeruginosa virulence by Garvis, Steven, Munder, Antje, Ball, Geneviève, de Bentzmann, Sophie, Wiehlmann, Lutz, Ewbank, Jonathan J, Tümmler, Burkhard, Filloux, Alain

“…Pseudomonas aeruginosa is an opportunistic human pathogen that causes infections in a variety of animal and plant hosts. Caenorhabditis elegans is a simple…”
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