Search Results - "Evrard, Maximilien"
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The highs and lows of CD4+ tissue-resident T cells in lung fibrosis
Published in Nature immunology (01-11-2019)“…Chronic exposure to fungal antigen drives the development of two subsets of CD4 + T RM cells, distinguished by high or low expression of the integrin CD103,…”
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Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity
Published in Nature immunology (01-08-2020)“…Adoptive cell therapies using genetically engineered T cell receptor or chimeric antigen receptor T cells are emerging forms of immunotherapy that redirect T…”
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Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions
Published in Immunity (Cambridge, Mass.) (20-02-2018)“…Neutrophils are specialized innate cells that require constant replenishment from proliferative bone marrow (BM) precursors as a result of their short…”
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Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity
Published in Nature immunology (01-09-2021)“…Tissue-resident memory T (T RM ) cells are non-recirculating cells that exist throughout the body. Although T RM cells in various organs rely on common…”
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Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen
Published in Immunity (Cambridge, Mass.) (21-08-2018)“…The maintenance of appropriate arterial tone is critically important for normal physiological arterial function. However, the cellular and molecular mechanisms…”
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A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment
Published in Immunity (Cambridge, Mass.) (15-08-2017)“…The liver is positioned at the interface between two routes traversed by pathogens in disseminating infection. Whereas blood-borne pathogens are efficiently…”
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Sphingosine 1-phosphate receptor 5 (S1PR5) regulates the peripheral retention of tissue-resident lymphocytes
Published in The Journal of experimental medicine (03-01-2022)“…Tissue-resident memory T (TRM) cells provide long-lasting immune protection. One of the key events controlling TRM cell development is the local retention of…”
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Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection
Published in Nature communications (16-07-2021)“…Mucosal-associated Invariant T (MAIT) cells are recognized for their antibacterial functions. The protective capacity of MAIT cells has been demonstrated in…”
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Neutrophils contribute to inflammatory lymphangiogenesis by increasing VEGF-A bioavailability and secreting VEGF-D
Published in Blood (21-11-2013)“…Lymphangiogenesis is an important physiological response to inflammatory insult, acting to limit inflammation. Macrophages, dendritic cells, and lymphocytes…”
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A Neutrophil Timer Coordinates Immune Defense and Vascular Protection
Published in Immunity (Cambridge, Mass.) (19-11-2019)Get full text
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Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow
Published in The Journal of experimental medicine (21-10-2013)“…Blood neutrophil homeostasis is essential for successful host defense against invading pathogens. Circulating neutrophil counts are positively regulated by…”
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Prior infection with unrelated neurotropic virus exacerbates influenza disease and impairs lung T cell responses
Published in Nature communications (23-03-2024)“…Immunity to infectious diseases is predominantly studied by measuring immune responses towards a single pathogen, although co-infections are common. In-depth…”
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The impact of ischemia‐reperfusion injuries on skin resident murine dendritic cells
Published in European journal of immunology (01-06-2018)“…Pressure ulcers are a chronic problem for patients or the elderly who require extended periods of bed rest. The formation of ulcers is due to repeated cycles…”
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Transitional premonocytes emerge in the periphery for host defense against bacterial infections
Published in Science advances (04-03-2022)“…Circulating Ly6C monocytes often undergo cellular death upon exhaustion of their antibacterial effector functions, which limits their capacity for subsequent…”
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Streamlining volumetric multi-channel image cytometry using hue-saturation-brightness-based surface creation
Published in Communications biology (01-01-2018)“…Image cytometry is the process of converting image data to flow cytometry-style plots, and it usually requires computer-aided surface creation to extract out…”
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The highs and lows of CD4.sup.+ tissue-resident T cells in lung fibrosis
Published in Nature immunology (01-11-2019)“…Chronic exposure to fungal antigen drives the development of two subsets of CD4.sup.+ T.sub.RM cells, distinguished by high or low expression of the integrin…”
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Cutting edge: the NLRP3 inflammasome links complement-mediated inflammation and IL-1β release
Published in The Journal of immunology (1950) (01-08-2013)“…The complement system is a potent component of the innate immune response, promoting inflammation and orchestrating defense against pathogens. However,…”
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A Neutrophil Timer Coordinates Immune Defense and Vascular Protection
Published in Immunity (Cambridge, Mass.) (19-02-2019)“…Neutrophils eliminate pathogens efficiently but can inflict severe damage to the host if they over-activate within blood vessels. It is unclear how immunity…”
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