Search Results - "Evgen'ev, Michael B."

Cytoplasmic aggregation of mutant FUS causes multistep RNA splicing perturbations in the course of motor neuron pathology by Rezvykh, Alexander P, Ustyugov, Aleksey A, Chaprov, Kirill D, Teterina, Ekaterina V, Nebogatikov, Vladimir O, Spasskaya, Daria S, Evgen’ev, Michael B, Morozov, Alexey V, Funikov, Sergei Yu

“…Abstract Dysfunction of the RNA-binding protein (RBP) FUS implicated in RNA metabolism can cause amyotrophic lateral sclerosis (ALS) and other…”
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A partial genome assembly of the miniature parasitoid wasp, Megaphragma amalphitanum by Sharko, Fedor S, Nedoluzhko, Artem V, Lê, Brandon M, Tsygankova, Svetlana V, Boulygina, Eugenia S, Rastorguev, Sergey M, Sokolov, Alexey S, Rodriguez, Fernando, Mazur, Alexander M, Polilov, Alexey A, Benton, Richard, Evgen'ev, Michael B, Arkhipova, Irina R, Prokhortchouk, Egor B, Skryabin, Konstantin G

“…Body size reduction, also known as miniaturization, is an important evolutionary process that affects a number of physiological and phenotypic traits and helps…”
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Spontaneous gain of susceptibility suggests a novel mechanism of resistance to hybrid dysgenesis in Drosophila virilis by Funikov, Sergei Y, Kulikova, Dina A, Krasnov, George S, Rezvykh, Alexander P, Chuvakova, Lubov N, Shostak, Natalia G, Zelentsova, Elena S, Blumenstiel, Justin P, Evgen'ev, Michael B

“…Syndromes of hybrid dysgenesis (HD) have been critical for our understanding of the transgenerational maintenance of genome stability by piRNA. HD in D…”
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The Role of Hsp70 in Adaptation to Adverse Conditions and Its Possible Medical Application by Evgen'ev, Michael B, Onikienko, Sergei B, Chuvakova, Lubov N, Garbuz, David G, Zatsepina, Olga G

“…In the present era of global warming and dramatically increased environmental pollution posing a threat to animal life, the understanding and manipulation of…”
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The Fate of Exogenous Human HSP70 Introduced into Animal Cells by Different Means by Yurinskaya, Marina, Zatsepina, Olga G, Vinokurov, Maxim G, Bobkova, Natalia V, Garbuz, David G, Morozov, Alexei V, Kulikova, Dina A, Mitkevich, Vladimir A, Makarov, Alexander A, Funikov, Sergei Yu, Evgen'ev, Michael B

“…Over the last decade, it has become evident that in mammals, including humans, heat shock protein 70 (HSP70), apart from its intracellular localization, is…”
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The development of modified human Hsp70 (HSPA1A) and its production in the milk of transgenic mice by Gurskiy, Yaroslav G., Garbuz, David G., Soshnikova, Nataliya V., Krasnov, Aleksey N., Deikin, Alexei, Lazarev, Vladimir F., Sverchinskyi, Dmitry, Margulis, Boris A., Zatsepina, Olga G., Karpov, Vadim L., Belzhelarskaya, Svetlana N., Feoktistova, Evgenia, Georgieva, Sofia G., Evgen'ev, Michael B.

“…The production of major human heat shock protein Hsp70 (HSPA1A) in a eukaryotic expression system is needed for testing and possible medical applications. In…”
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Functional organization of hsp70 cluster in camel (Camelus dromedarius) and other mammals by Garbuz, David G, Astakhova, Lubov N, Zatsepina, Olga G, Arkhipova, Irina R, Nudler, Eugene, Evgen'ev, Michael B

“…Heat shock protein 70 (Hsp70) is a molecular chaperone providing tolerance to heat and other challenges at the cellular and organismal levels. We sequenced a…”
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Organization and evolution of hsp70 clusters strikingly differ in two species of Stratiomyidae (Diptera) inhabiting thermally contrasting environments by Garbuz, David G, Yushenova, Irina A, Zatsepina, Olga G, Przhiboro, Andrey A, Bettencourt, Brian R, Evgen'ev, Michael B

“…Previously, we described the heat shock response in dipteran species belonging to the family Stratiomyidae that develop in thermally and chemically contrasting…”
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Medium-sized tandem repeats represent an abundant component of the Drosophila virilis genome by Abdurashitov, Murat A, Gonchar, Danila A, Chernukhin, Valery A, Tomilov, Victor N, Tomilova, Julia E, Schostak, Natalia G, Zatsepina, Olga G, Zelentsova, Elena S, Evgen'ev, Michael B, Degtyarev, Sergey K H

“…Previously, we developed a simple method for carrying out a restriction enzyme analysis of eukaryotic DNA in silico, based on the known DNA sequences of the…”
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Expression of Drosophila virilis Retroelements and Role of Small RNAs in Their Intrastrain Transposition by Rozhkov, Nikolay V, Zelentsova, Elena S, Shostak, Natalia G, Evgen'ev, Michael B

“…Transposition of two retroelements (Ulysses and Penelope) mobilized in the course of hybrid dysgenesis in Drosophila virilis has been investigated by in situ…”
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What happens when Penelope comes?: An unusual retroelement invades a host species genome exploring different strategies by Evgen'ev, Michael B.

“…Transposable elements (TEs) are ubiquitous residents in eukaryotic genomes. They can cause dramatic changes in gene expression and lead to gross rearrangements…”
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The role of molecular chaperones in the mechanisms of epileptogenesis by Davletshin, Artem I., Matveeva, Anna A., Poletaeva, Inga I., Evgen’ev, Michael B., Garbuz, David G.

“…Epilepsy is a group of neurological diseases which requires significant economic costs for the treatment and care of patients. The central point of…”
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Cell-Permeable HSP70 Protects Neurons and Astrocytes Against Cell Death in the Rotenone-Induced and Familial Models of Parkinson’s Disease by Vinokurov, Andrey Y., Palalov, Alexander A., Kritskaya, Kristina A., Demyanenko, Svetlana V., Garbuz, David G., Evgen’ev, Michael B., Esteras, Noemi, Abramov, Andrey Y.

“…Heat shock protein 70 (HSP70) is activated under stress response. Its involvement in cell protection, including energy metabolism and quality control makes it…”
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Exogenous Hsp70 exerts neuroprotective effects in peripheral nerve rupture model by Demyanenko, Svetlana V., Kalyuzhnaya, Yuliya N., Bachurin, Stanislav S., Khaitin, Andrey M., Kunitsyna, Anastasia E., Batalshchikova, Svetlana A., Evgen'ev, Michael B., Garbuz, David G.

“…Hsp70 is the main molecular chaperone responsible for cellular proteostasis under normal conditions and for restoring the conformation or utilization of…”
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Role of a Heat Shock Transcription Factor and the Major Heat Shock Protein Hsp70 in Memory Formation and Neuroprotection by Zatsepina, Olga G., Evgen’ev, Michael B., Garbuz, David G.

“…Heat shock proteins (Hsps) represent the most evolutionarily ancient, conserved, and universal system for protecting cells and the whole body from various…”
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Adaptation of gene loci to heterochromatin in the course of Drosophila evolution is associated with insulator proteins by Funikov, Sergei Yu, Rezvykh, Alexander P., Kulikova, Dina A., Zelentsova, Elena S., Protsenko, Lyudmila A., Chuvakova, Lyubov N., Tyukmaeva, Venera I., Arkhipova, Irina R., Evgen’ev, Michael B.

“…Pericentromeric heterochromatin is generally composed of repetitive DNA forming a transcriptionally repressive environment. Dozens of genes were embedded into…”
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Reverse Transcriptase and Endonuclease Activities Encoded by Penelope-Like Retroelements by Pyatkov, Konstantin I., Arkhipova, Irina R., Malkova, Natalia V., Finnegan, David J., Michael B. Evgen'ev, Meselson, M. S.

“…Penelope-like elements are a class of retroelement that have now been identified in >50 species belonging to at least 10 animal phyla. The Penelope element…”
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Exogenous heat shock protein 70 mediates sepsis manifestations and decreases the mortality rate in rats by Kustanova, Gul'sara A., Murashev, Arcady N., Karpov, Vadim L., Margulis, Boris A., Guzhova, Irina V., Prokhorenko, Izabella R., Grachev, Sergei V., Evgen'ev, Michael B.

“…Mammalian responses to bacterial lipopolysaccharide (LPS) from the outer membrane of Gram-negative bacteria can lead to an uncontrolled inflammatory reaction…”
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The molecular chaperone Hsp70 from the thermotolerant Diptera species differs from the Drosophila paralog in its thermostability and higher refolding capacity at extreme temperatures by Garbuz, David G., Sverchinsky, Dmitry, Davletshin, Artem, Margulis, Boris A., Mitkevich, Vladimir, Kulikov, Aleksei M., Evgen'ev, Michael B.

“…Previously, we demonstrated that species of the Stratiomyidae family exhibit higher tolerance to thermal stress in comparison with that of many representatives…”
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Mobile Elements and Chromosomal Evolution in the Virilis Group of Drosophila by Michael B. Evgen'ev, Zelentsova, Helena, Poluectova, Helena, Lyozin, George T., Veleikodvorskaja, Vera, Pyatkov, K. I., Zhivotovsky, Lev A., Kidwell, Margaret G.

“…Species of the virilis group of Drosophila differ by multiple inversions and chromosome fusions that probably accompanied, or led to, speciation. Drosophila…”
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