Search Results - "Evgen'ev, M."

The Protective Action of Hsp70 and Hydrogen Sulfide Donors in THP-1 Macrophages in the Lipopolysaccharide-Induced Inflammatory Response by Modulating Endocytosis by Yurinskaya, M. M., Garbuz, D. G., Evgen’ev, M. B., Vinokurov, M. G.

“…—Hsp70 and hydrogen sulfide donors reduce inflammatory processes in human and animal cells. The biological action mediated by Hsp70 and H 2 S donors (GYY4137…”
Get full text

Beta Amyloid, Tau Protein, and Neuroinflammation: An Attempt to Integrate Different Hypotheses of Alzheimer’s Disease Pathogenesis by Garbuz, D. G., Zatsepina, O. G., Evgen’ev, M. B.

“…Alzheimer’s disease (AD) is a neurodegenerative disease that inevitably results in dementia and death. Currently, there are no pathogenetically grounded…”
Get full text

The Major Human Stress Protein Hsp70 as a Factor of Protein Homeostasis and a Cytokine-Like Regulator by Garbuz, D. G., Zatsepina, O. G., Evgen’ev, M. B.

“…Heat shock proteins (HSPs) are important factors of protein homeostasis and possess chaperone properties, providing for a folding and intracellular transport…”
Get full text

Expression patterns and organization of the hsp70 genes correlate with thermotolerance in two congener endemic amphipod species (Eulimnogammarus cyaneus and E. verrucosus) from Lake Baikal by Bedulina, D. S., Evgen'ev, M. B., Timofeyev, M. A., Protopopova, M. V., Garbuz, D. G., Pavlichenko, V. V., Luckenbach, T., Shatilina, Z. M., Axenov-Gribanov, D. V., Gurkov, A. N., Sokolova, I. M., Zatsepina, O. G.

“…We studied various aspects of heat‐shock response with special emphasis on the expression of heat‐shock protein 70 (hsp70) genes at various levels in two…”
Get full text

Genome-wide transcriptional effects of deletions of sulphur metabolism genes in Drosophila melanogaster by Zatsepina, O., Karpov, D., Chuvakova, L., Rezvykh, A., Funikov, S., Sorokina, S., Zakluta, A., Garbuz, D., Shilova, V., Evgen'ev, M.

“…In recent years, the gasotransmitter hydrogen sulphide (H2S), produced by the transsulphuration pathway, has been recognized as a biological mediator playing…”
Get full text

HSP70 protects human neuroblastoma cells from apoptosis and oxidative stress induced by amyloid peptide isoAsp7-Aβ(1–42) by Yurinskaya, M M, Mitkevich, V A, Kozin, S A, Evgen'ev, M B, Makarov, A A, Vinokurov, M G

Get full text

Exogenous HSP70 and Signaling Pathways Involved in the Inhibition of LPS-Induced Neurotoxicity of Neuroblastoma Cells by Yurinskaya, M. M., Garbuz, D. G., Evgen’ev, M. B., Vinokurov, M. G.

“…Neuroinflammation plays a key role in the pathogenesis of neurodegenerative diseases. Microglial cells are the main immune cells of the central nervous system…”
Get full text

The evolution of heat shock genes and expression patterns of heat shock proteins in the species from temperature contrasting habitats by Garbuz, D. G., Evgen’ev, M. B.

“…Heat shock genes are the most evolutionarily ancient among the systems responsible for adaptation of organisms to a harsh environment. The encoded proteins…”
Get full text

Effects of the Hydrogen Sulfide Donor GYY4137 and HSP70 Protein on the Activation of SH-SY5Y Cells by Lipopolysaccharide by Yurinskaya, M. M., Garbuz, D. G., Afanasiev, V. N., Evgen’ev, M. B., Vinokurov, M. G.

“…The effects of exogenous recombinant human heat shock protein Hsp70 and hydrogen sulfide donor GYY4137 on the mechanisms of endocytosis of lipopolysaccharide…”
Get full text

Heat shock protein 70 from a thermotolerant Diptera species provides higher thermoresistance to Drosophila larvae than correspondent endogenous gene by Shilova, V. Y., Zatsepina, O. G., Garbuz, D. G., Funikov, S. Y., Zelentsova, E. S., Schostak, N. G., Kulikov, A. M., Evgen'ev, M. B.

“…Heat shock proteins (Hsp70s) from two Diptera species that drastically differ in their heat shock response and longevity were investigated. Drosophila…”
Get full text

Exogenous HSP70 and Signaling Pathways Involved in the Inhibition of LPS-Induced Neurotoxicity of Neuroblastoma Cells by Yurinskaya, M M, Garbuz, D G, Evgen'ev, M B, Vinokurov, M G

“…Neuroinflammation plays a key role in the pathogenesis of neurodegenerative diseases. Microglial cells are the main immune cells of the central nervous system…”
Get more information

A Drosophila heat shock response represents an exception rather than a rule amongst Diptera species by Zatsepina, O. G., Przhiboro, A. A., Yushenova, I. A., Shilova, V., Zelentsova, E. S., Shostak, N. G., Evgen'ev, M. B., Garbuz, D. G.

“…Heat shock protein 70 (Hsp70) is the major player that underlies adaptive response to hyperthermia in all organisms studied to date. We investigated patterns…”
Get full text

Effect of Heat Shock Proteins on Life Span and Behavioral Functions of Animals with FUS Proteinopathy by Vikhareva, E. A., Chicheva, M. M., Evgen’ev, M. B., Funikov, S. Yu, Deikin, A. V., Bachurin, S. O., Ustyugov, A. A.

“…—It is known that chaperones and, in particular, 70 kDa heat shock proteins (HSP70), are an integral part of cellular proteostasis. To assess the role of HSP70…”
Get full text

Effects of the Hydrogen Sulfide Donor GYY4137 and HSP70 Protein on the Activation of SH-SY5Y Cells by Lipopolysaccharide by Yurinskaya, M M, Garbuz, D G, Afanasiev, V N, Evgen'ev, M B, Vinokurov, M G

“…The effects of exogenous recombinant human heat shock protein Hsp70 and hydrogen sulfide donor GYY4137 on the mechanisms of endocytosis of lipopolysaccharide…”
Get more information

Heat-shock protein HSP70 reduces the secretion of TNFα by neuroblastoma cells and human monocytes induced with beta-amyloid peptides by Yurinskaya, M. M., Mit’kevich, V. A., Evgen’ev, M. B., Makarov, A. A., Vinokurov, M. G.

“…The progress of neurodegeneration in Alzheimer’s disease is closely associated with inflammatory processes in the brain tissues induced by beta-amyloid…”
Get full text

Exogenous heat shock protein HSP70 reduces response of human neuroblastoma cells to lipopolysaccharide by Yurinskaya, M. M., Funikov, S. Y., Evgen’ev, M. B., Vinokurov, M. G.

“…The effect of exogenous heat shock protein HSP70 and lipopolysaccharide (LPS) on the production of reactive oxygen species (ROS), TNFα secretion, and mRNA…”
Get full text

Novel arrangement and comparative analysis of hsp90 family genes in three thermotolerant species of Stratiomyidae (Diptera) by Astakhova, L. N., Zatsepina, O. G., Przhiboro, A. A., Evgen'ev, M. B., Garbuz, D. G.

“…The heat shock proteins belonging to the Hsp90 family (Hsp83 in Diptera) play a crucial role in the protection of cells due to their chaperoning functions. We…”
Get full text

Penelope-like elements--a new class of retroelements: distribution, function and possible evolutionary significance by Evgen'ev, M B, Arkhipova, I R

“…Here we describe a new class of retroelements termed PLE (Penelope-like elements). The only transpositionally active representative of this lineage found so…”
Get more information

Comparative analysis of effectiveness of heat-shock promoters in two Diptera species by Astakhova, L. N., Zatsepina, O. G., Evgen’ev, M. B., Garbuz, D. G.

“…Heat-shock proteins (Hsp) provide the cellular and full-body adaptation of animals to various adverse environmental conditions. The hsp70 is believed to play a…”
Get full text

Molecular mechanisms underlying thermal adaptation of xeric animals by Evgen'ev, M B, Garbuz, D G, Shilova, V Y, Zatsepina, O G

“…For many years,we and our collaborators have investigated the adaptive role of heat shock proteins in different animals,including the representatives of…”
Get full text