Search Results - "Everitt, B J"

In search of predictive endophenotypes in addiction: insights from preclinical research by Belin, D., Belin‐Rauscent, A., Everitt, B. J., Dalley, J. W.

“…Drug addiction is widely recognized to afflict some but not all individuals by virtue of underlying risk markers and traits involving multifaceted interactions…”
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Drug Addiction and the Memory Systems of the Brain by Robbins, T.W., Ersche, K.D., Everitt, B.J.

“…We review drug addiction from the perspective of the hypothesis that drugs of abuse interact with distinct brain memory systems. We focus on emotional and…”
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Decrease of cocaine, but not heroin, self-administration and relapse by the tyrosine kinase inhibitor masitinib in male Sprague Dawley rats by Belin-Rauscent, A., Lacoste, J., Hermine, O., Moussy, A., Everitt, B. J., Belin, David

“…Rationale Accumulating evidence shows that cocaine, and also heroin, influence several tyrosine kinases, expressed in neurons and in non-neuronal populations…”
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Selective Behavioral and Neurochemical Effects of Cholinergic Lesions Produced by Intrabasalis Infusions of 192 IgG-Saporin on Attentional Performance in a Five-Choice Serial Reaction Time Task by McGaughy, J, Dalley, J. W, Morrison, C. H, Everitt, B. J, Robbins, T. W

“…The effects of the cholinergic immunotoxin 192 IgG-saporin (SAP) (0.0, 0.15, or 0.45 microg/microl; 0.5 microl/hemisphere) infused into the area of the nucleus…”
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Limbic-Striatal Memory Systems and Drug Addiction by Robbins, T.W, Everitt, B.J

“…Drug addiction can be understood as a pathological subversion of normal brain learning and memory processes strengthened by the motivational impact of…”
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Profiles of cognitive dysfunction in chronic amphetamine and heroin abusers by ORNSTEIN, T. J, IDDON, J. L, BALDACCHINO, A. M, SAHAKIAN, B. J, LONDON, M, EVERITT, B. J, ROBBINS, T. W

“…Groups of subjects whose primary drug of abuse was amphetamine or heroin were compared, together with age- and IQ-matched control subjects. The study consisted…”
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The role of withdrawal in heroin addiction: enhances reward or promotes avoidance? by Hutcheson, D. M, Everitt, B. J, Robbins, T. W, Dickinson, A

“…The compulsive nature of heroin abuse has been attributed to the fact that drug self-administration enables an addict to escape from and avoid the severe…”
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Acquisition, maintenance and reinstatement of intravenous cocaine self-administration under a second-order schedule of reinforcement in rats : effects of conditioned cues and continuous access to cocaine by ARROYO, M, MARKOU, A, ROBBINS, T. W, EVERITT, B. J

“…Second order schedules of IV cocaine reinforcement in rats provide a reliable method for evaluating the effects of conditioned stimuli on cocaine-seeking…”
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Impulsive Choice Induced in Rats by Lesions of the Nucleus Accumbens Core by Cardinal, Rudolf N., Pennicott, David R., Sugathapala, C. Lakmali, Robbins, Trevor W., Everitt, Barry J.

“…Impulsive choice is exemplified by choosing a small or poor reward that is available immediately, in preference to a larger but delayed reward. Impulsive…”
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Increased acetylcholine release in the rat medial prefrontal cortex during performance of a visual attentional task by Passetti, F., Dalley, J. W., O'connell, M. T., Everitt, B. J., Robbins, T. W.

“…Recent studies have suggested a functional link between cortical cholinergic output and attentional task demands, whereby acetylcholine (ACh) release is…”
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Central cholinergic systems and cognition by EVERITT, B. J, ROBBINS, T. W

“…The organization and possible functions of basal forebrain and pontine cholinergic systems are reviewed. Whereas the basal forebrain cholinergic neuronal…”
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Involvement of the central nucleus of the amygdala and nucleus accumbens core in mediating Pavlovian influences on instrumental behaviour by Hall, Jeremy, Parkinson, John A., Connor, Thomas M., Dickinson, Anthony, Everitt, Barry J.

“…Pavlovian conditioned cues exert a powerful influence on instrumental actions directed towards a common reward, this is known as Pavlovian‐to‐instrumental…”
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Second-order schedules of drug reinforcement in rats and monkeys: measurement of reinforcing efficacy and drug-seeking behaviour by Everitt, B J, Robbins, T W

“…To review the literature on the use of second-order schedules of drug reinforcement in the context of experimental investigations of the neural and…”
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Different types of fear-conditioned behaviour mediated by separate nuclei within amygdala by Killcross, Simon, Robbins, Trevor W, Everitt, Barry J

“…The amygdala has long been thought to be involved in emotional behaviour, and its role in anxiety and conditioned fear has been highlighted. Individual…”
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Dissociable Deficits in the Decision-Making Cognition of Chronic Amphetamine Abusers, Opiate Abusers, Patients with Focal Damage to Prefrontal Cortex, and Tryptophan-Depleted Normal Volunteers: Evidence for Monoaminergic Mechanisms by Rogers, R.D, Everitt, B.J, Baldacchino, A, Blackshaw, A.J, Swainson, R, Wynne, K, Baker, N.B, Hunter, J, Carthy, T, Booker, E, London, M, Deakin, J.F.W, Sahakian, B.J, Robbins, T.W

“…We used a novel computerized decision-making task to compare the decision-making behavior of chronic amphetamine abusers, chronic opiate abusers, and patients…”
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Differential Involvement of NMDA, AMPA/Kainate, and Dopamine Receptors in the Nucleus Accumbens Core in the Acquisition and Performance of Pavlovian Approach Behavior by Di Ciano, Patricia, Cardinal, Rudolf N, Cowell, Rosie A, Little, Simon J, Everitt, Barry J

“…Stimuli paired with primary rewards can acquire emotional valence and the ability to elicit automatic, Pavlovian approach responses that have been shown to be…”
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Dissociation in Conditioned Dopamine Release in the Nucleus Accumbens Core and Shell in Response to Cocaine Cues and during Cocaine-Seeking Behavior in Rats by Ito, Rutsuko, Dalley, Jeffrey W, Howes, Simon R, Robbins, Trevor W, Everitt, Barry J

“…The dopaminergic innervation of the nucleus accumbens is generally agreed to mediate the primary reinforcing and locomotor effects of psychostimulants, but…”
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Neural and psychological mechanisms underlying appetitive learning: links to drug addiction by Cardinal, Rudolf N, Everitt, Barry J

“…The complexity of drug addiction mirrors the complexity of the psychological processes that motivate animals to work for any reinforcer, be it a natural reward…”
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The effects of d-amphetamine, chlordiazepoxide, α-flupenthixol and behavioural manipulations on choice of signalled and unsignalled delayed reinforcement in rats by CARDINAL, Rudolf N, ROBBINS, Trevor W, EVERITT, Barry J

“…Inability to tolerate delays to reward is an important component of impulsive behaviour, and has been suggested to reflect dysfunction of dopamine systems. The…”
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Nucleus accumbens dopamine depletion impairs both acquisition and performance of appetitive Pavlovian approach behaviour: implications for mesoaccumbens dopamine function by Parkinson, J.A, Dalley, J.W, Cardinal, R.N, Bamford, A, Fehnert, B, Lachenal, G, Rudarakanchana, N, Halkerston, K.M, Robbins, T.W, Everitt, B.J

“…The involvement of mesoaccumbens dopamine in adaptive learning and behaviour is unclear. For example, dopamine may act as a teaching signal to enable learning,…”
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