Search Results - "Everhart, Angela"
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Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease
Published in The Journal of neuroscience (15-04-2015)“…The pathogenesis of Alzheimer's disease (AD) is a critical unsolved question; and although recent studies have demonstrated a strong association between…”
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Metabolism-Based Gene Differences in Neurons Expressing Hyperphosphorylated AT8− Positive (AT8+) Tau in Alzheimer’s Disease
Published in ASN neuro (2021)“…Metabolic adaptations in the brain are critical to the establishment and maintenance of normal cellular functions and to the pathological responses to disease…”
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Lithium treatment of APPSwDI/NOS2-/- mice leads to reduced hyperphosphorylated tau, increased amyloid deposition and altered inflammatory phenotype
Published in PloS one (09-02-2012)“…Lithium is an anti-psychotic that has been shown to prevent the hyperphosphorylation of tau protein through the inhibition of glycogen-synthase kinase 3-beta…”
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4
Diverse inflammatory responses in transgenic mouse models of Alzheimer's disease and the effect of immunotherapy on these responses
Published in ASN neuro (30-11-2011)“…While the presence of an inflammatory response in AD (Alzheimer's disease) is well known, the data on inflammation are conflicting, suggesting that…”
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Interacting Effects of N-terminal Variation and Strex Exon Splicing on slo Potassium Channel Regulation by Calcium, Phosphorylation, and Oxidation
Published in The Journal of biological chemistry (26-07-2002)“…We have investigated the structural basis for the phenotype of a native rat Slo (rSlo) potassium channel (BKCa; KCNMA1) in a rat pituitary cell line, GH4C1…”
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P2‐168: IMMUNE‐REGULATED METABOLIC PATHWAY ANALYSIS IN AT8‐POSITIVE NEURONS USING LASER CAPTURE MICROSCOPY
Published in Alzheimer's & dementia (01-07-2018)Get full text
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IMMUNE-REGULATED METABOLIC PATHWAY ANALYSIS IN AT8-POSITIVE NEURONS USING LASER CAPTURE MICROSCOPY
Published in Alzheimer's & dementia (01-07-2018)Get full text
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8
Longitudinal Study of Differential Protein Expression in an Alzheimer’s Mouse Model Lacking Inducible Nitric Oxide Synthase
Published in Journal of proteome research (04-10-2013)“…Alzheimer’s disease (AD) is a complex neurodegenerative process that involves altered brain immune, neuronal and metabolic functions. Understanding the…”
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9
mNos2 Deletion and Human NOS2 Replacement in Alzheimer Disease Models
Published in Journal of neuropathology and experimental neurology (01-08-2014)“…ABSTRACTUnderstanding the pathophysiologic mechanisms underlying Alzheimer disease relies on knowledge of disease onset and the sequence of development of…”
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10
The impact of human and mouse differences in NOS2 gene expression on the brain's redox and immune environment
Published in Molecular neurodegeneration (17-11-2014)“…Mouse models are used in the study of human disease. Despite well-known homologies, the difference in immune response between mice and humans impacts the…”
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11
Entertaining a False Reality: A social comparison examination of beauty pageant participation and the effect on body dissatisfaction, depression, and self-esteem
Published 01-01-2011“…This study investigated the effects of beauty pageant participation on body dissatisfaction, depression, and self-esteem among women. A group of 20 women who…”
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Dissertation -
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The Linoleic Acid Metabolite, (13S)-Hydroperoxyoctadecadienoic Acid, Augments the Epidermal Growth Factor Receptor Signaling Pathway by Attenuation of Receptor Dephosphorylation
Published in The Journal of biological chemistry (01-08-1997)“…In Syrian hamster embryo (SHE) fibroblasts, epidermal growth factor receptor (EGFR) tyrosine kinase activity regulates the metabolism of endogenous linoleic…”
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13
The linoleic acid metabolite, (13S)-hydroperoxyoctadecadienoic acid, augments the epidermal growth factor receptor signaling pathway by attenuation of receptor dephosphorylation. Differential response in Syrian hamster embryo tumor suppressor phenotypes
Published in The Journal of biological chemistry (01-08-1997)“…In Syrian hamster embryo (SHE) fibroblasts, epidermal growth factor receptor (EGFR) tyrosine kinase activity regulates the metabolism of endogenous linoleic…”
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Characterization of a 15-Lipoxygenase in Human Breast Carcinoma BT-20 Cells: Stimulation of 13-HODE Formation by TGFα/EGF
Published in Biochemical and biophysical research communications (03-02-1997)“…Epidemiological and experimental data suggest a role for polyunsaturated fatty acids in the etiology of breast cancer. In this report we have studied…”
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Epidermal growth factor-stimulated production of esterified 13(S)-hydroxyoctadecadienoic acid is associated with tumor suppressor phenotype in Syrian hamster embryo fibroblasts
Published in Journal of lipid research (01-01-1997)“…Epidermal growth factor (EGF) stimulates the lipoxygenase metabolism of linoleic acid to 13(S)-hydroxyoctadecadienoic acid (HODE) in Syrian hamster embryo…”
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