Search Results - "Eveleth, D D"
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Healing of Ocular Herpetic Disease Following Treatment With an Engineered FGF-1 Is Associated With Increased Corneal Anti-Inflammatory M2 Macrophages
Published in Frontiers in immunology (13-05-2021)“…Herpes simplex virus 1 (HSV-1) infects the cornea and caused blinding ocular disease. In the present study, we evaluated whether and how a novel engineered…”
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Novel Peptidyl α-Keto Amide Inhibitors of Calpains and Other Cysteine Proteases
Published in Journal of medicinal chemistry (27-09-1996)“…A series of new dipeptidyl α-keto amides of the general structure R1-l-Leu-d,l-AA-CONH-R2 were synthesized and evaluated as inhibitors for the cysteine…”
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An Engineered Human Fibroblast Growth Factor-1 Derivative, TTHX1114, Ameliorates Short-term Corneal Nitrogen Mustard Injury in Rabbit Organ Cultures
Published in Investigative ophthalmology & visual science (01-09-2018)“…Organ cultures of rabbit corneas have been used to ascertain the effectiveness of a human fibroblast growth factor (FGF)-1 derivative (TTHX1114), lacking…”
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Regenerative responses of rabbit corneal endothelial cells to stimulation by fibroblast growth factor 1 (FGF1) derivatives, TTHX1001 and TTHX1114
Published in Growth factors (Chur, Switzerland) (28-07-2021)“…Utilising rabbit corneal endothelial cells (CEC) in three different paradigms, two human FGF1 derivatives (TTHX1001 and TTHX1114), engineered to exhibit…”
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Cell-based therapies for ocular disease
Published in Journal of ocular pharmacology and therapeutics (01-12-2013)“…Cell therapy for ocular disease has made significant progress within the last decade. Stem and progenitor populations for many ocular cell types have been…”
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Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteases
Published in Journal of medicinal chemistry (29-10-1993)“…A series of dipeptidyl and tripeptidyl alpha-keto esters, alpha-keto amides, and alpha-keto acids having leucine in the P2 position were synthesized and…”
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Local cerebral glucose utilization and cytoskeletal proteolysis as indices of evolving focal ischemic injury in core and penumbra
Published in Journal of cerebral blood flow and metabolism (01-05-1995)“…To ascertain the tempo of progression to irreversible injury in focal ischemia, we subjected halothane-anesthetized Sprague-Dawley rats to photochemically…”
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Differential induction of primary-response (TIS) genes in PC12 pheochromocytoma cells and the unresponsive variant PC12nnr5
Published in The Journal of biological chemistry (25-03-1991)“…As a measure of the transmembrane signals that they transduce, two neurotrophic agents, nerve growth factor (NGF) and basic fibroblast growth factor (bFGF),…”
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Nerve Growth Factor Nonresponsive Pheochromocytoma Cells: Altered Internalization Results in Signaling Dysfunction
Published in The Journal of cell biology (01-04-1992)“…Variant rat pheochromocytoma (PC12) cells which fail to respond to nerve growth factor (NGF) (PC12nnr5) (Green, S. H., R. E. Rydel, J. L. Connoly, and L. A…”
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Sequence and expression of the Cc gene, a member of the dopa decarboxylase gene cluster of Drosophila: possible translational regulation
Published in Nucleic acids research (11-08-1986)“…A transcript has been localized proximal to the dopa decarboxylase (Ddc) gene within a cluster of genes involved in cuticle formation and catecholamine…”
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Sequence and structure of the dopa decarboxylase gene of Drosophila: evidence for novel RNA splicing variants
Published in The EMBO journal (01-10-1986)“…In Drosophila, dopa decarboxylase (DDC) serves a dual role in neurotransmitter production and sclerotization of the cuticle. The Ddc gene is under complex…”
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Internalization and cycling of nerve growth factor in PC12 cells: interconversion of type II (fast) and type I (slow) nerve growth factor receptors
Published in Neuron (Cambridge, Mass.) (01-12-1988)“…The effects of agents that inhibit receptor-mediated endocytosis on type I (slow or high-affinity) and type II (fast or low-affinity) NGF binding have been…”
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Evidence for evolutionary duplication of genes in the dopa decarboxylase region of Drosophila
Published in Genetics (Austin) (01-10-1986)“…The region surrounding the dopa decarboxylase gene (Ddc) of Drosophila contains a cluster of genes, many of which appear to be functionally related by virtue…”
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Nerve Growth Factor Receptors: Structure and Function
Published in In Vitro Cellular & Developmental Biology (01-12-1988)Get full text
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Validity of Scores on Three Attachment Style Scales: Exploratory and Confirmatory Evidence
Published in Educational and psychological measurement (01-06-1997)“…Three attachment style scales were developed. The factor structure of the attachment style construct was supported through exploratory factor analysis of…”
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v-src genes stimulate neurite outgrowth in pheochromocytoma (PC12) variants unresponsive to neurotrophic factors
Published in Journal of neuroscience research (01-09-1989)“…The NGF-nonresponsive rat pheochromocytoma PC12 variant nnr5, isolated by Green et al. (J Cell Biol 102:830-843, 1986), responds poorly or not at all to…”
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Modulation of growth factor induced fiber outgrowth in rat pheochromocytoma (PC12) cells by a fibronectin receptor antibody
Published in Journal of cellular physiology (01-01-1989)“…Rat pheochromocytoma PC12 cells respond to the binding of nerve growth factor (NGF) and basic fibroblast growth factor (bFGF) by extending neurites in a manner…”
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Overlapping transcription units in Drosophila: sequence and structure of the Cs gene
Published in Molecular & general genetics (01-09-1987)“…The Cs gene lies between the functionally and evolutionarily related dopa decarboxylase (Ddc) and l(2)amd loci of Drosophila. The Cs and Ddc genes overlap at…”
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Peptide .alpha.-keto ester, .alpha.-keto amide, and .alpha.-keto acid inhibitors of calpains and other cysteine proteases
Published in Journal of medicinal chemistry (01-10-1993)Get full text
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