Search Results - "Eve Lemay, Sarah"

Right Ventricular Dysfunction in Pulmonary Hypertension: Is Resistin a Promising Target? by Lemay, Sarah-Eve, Grobs, Yann, Boucherat, Olivier

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Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival by Kudryashova, Tatiana V., Dabral, Swati, Nayakanti, Sreenath, Ray, Arnab, Goncharov, Dmitry A., Avolio, Theodore, Shen, Yuanjun, Rode, Analise, Pena, Andressa, Jiang, Lifeng, Lin, Derek, Baust, Jeffrey, Bachman, Timothy N., Graumann, Johannes, Ruppert, Clemens, Guenther, Andreas, Schmoranzer, Mario, Grobs, Yann, Eve Lemay, Sarah, Tremblay, Eve, Breuils-Bonnet, Sandra, Boucherat, Olivier, Mora, Ana L., DeLisser, Horace, Zhao, Jing, Zhao, Yutong, Bonnet, Sébastien, Seeger, Werner, Pullamsetti, Soni S., Goncharova, Elena A.

“…The MSTs (mammalian Ste20-like kinases) 1/2 are members of the HIPPO pathway that act as growth suppressors in adult proliferative diseases. Pulmonary arterial…”
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Prognostic Significance of Proteomics-Discovered Circulating Inflammatory Biomarkers in Patients With Pulmonary Arterial Hypertension by Yokokawa, Tetsuro, Boucherat, Olivier, Martineau, Sandra, Lemay, Sarah-Eve, Breuils-Bonnet, Sandra, Krishna, Vinod, Kalyana-Sundaram, Shanker, Jeyaseelan, Jey, Potus, François, Bonnet, Sébastien, Provencher, Steeve

“…Pulmonary arterial hypertension (PAH) ultimately leads to right ventricular failure and premature death. The identification of circulating biomarkers with…”
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Preclinical Investigation of Trifluoperazine as a Novel Therapeutic Agent for the Treatment of Pulmonary Arterial Hypertension by Grobs, Yann, Awada, Charifa, Lemay, Sarah-Eve, Romanet, Charlotte, Bourgeois, Alice, Toro, Victoria, Nadeau, Valérie, Shimauchi, Kana, Orcholski, Mark, Breuils-Bonnet, Sandra, Tremblay, Eve, Provencher, Steeve, Paulin, Roxane, Boucherat, Olivier, Bonnet, Sébastien

“…Trifluoperazine (TFP), an antipsychotic drug approved by the Food and Drug Administration, has been show to exhibit anti-cancer effects. Pulmonary arterial…”
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Fetal Gene Reactivation in Pulmonary Arterial Hypertension: GOOD, BAD, or BOTH? by Lemay, Sarah-Eve, Awada, Charifa, Shimauchi, Tsukasa, Wu, Wen-Hui, Bonnet, Sébastien, Provencher, Steeve, Boucherat, Olivier

“…Pulmonary arterial hypertension is a debilitating chronic disorder marked by the progressive obliteration of the pre-capillary arterioles. This imposes a…”
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Commentary on: Xbp1s-Ddit3, DNA damage and pulmonary hypertension by Lemay, Sarah-Eve, Bonnet, Sebastien, Potus, François

“…In this commentary, we discuss new observations stating that spliced X-box-binding protein 1 (Xbp1s)-DNA damage-inducible transcript 3 (Ddit3) promotes…”
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DNA-Protein Kinase Catalytic Subunit as a Potential Target for Pulmonary Arterial Hypertension by Yamamoto, Keiko, Lemay, Sarah-Eve, Yokokawa, Tetsuro, Breuils-Bonnet, Sandra, Salem, Mabrouka, Potus, François, Provencher, Steeve, Boucherat, Olivier, Bonnet, Sébastien

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G9a/GLP Targeting Ameliorates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension by Awada, Charifa, Bourgeois, Alice, Lemay, Sarah-Eve, Grobs, Yann, Yokokawa, Tetsuro, Breuils-Bonnet, Sandra, Martineau, Sandra, Krishna, Vinod, Potus, François, Jeyaseelan, Jey, Provencher, Steeve, Bonnet, Sébastien, Boucherat, Olivier

“…Pulmonary arterial hypertension (PAH) is characterized by progressive vascular remodeling of small pulmonary arteries (PAs) causing sustained elevation of PA…”
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Oxidized DNA Precursors Cleanup by NUDT1 Contributes to Vascular Remodeling in Pulmonary Arterial Hypertension by Vitry, Géraldine, Paulin, Roxane, Grobs, Yann, Lampron, Marie-Claude, Shimauchi, Tsukasa, Lemay, Sarah-Eve, Tremblay, Eve, Habbout, Karima, Awada, Charifa, Bourgeois, Alice, Nadeau, Valérie, Paradis, Renée, Breuils-Bonnet, Sandra, Roux-Dalvai, Florence, Orcholski, Mark, Potus, François, Provencher, Steeve, Boucherat, Olivier, Bonnet, Sébastien

“…Pulmonary arterial hypertension (PAH) is a life-threatening condition characterized by abnormally elevated pulmonary pressures and right ventricular failure…”
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Reverse Reaction of Nicotinamide Nucleotide Transhydrogenase Promotes ROS Production and Contributes to Right Ventricular Failure by Lemay, Sarah-Eve, Boucherat, Olivier, Bonnet, Sébastien

“…[Display omitted]…”
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Abstract 4143932: Exploring P300/CBP as therapeutic approach for right ventricular dysfunction in PAH by Bourgeois, Alice, Lemay, Sarah-Eve, Grobs, Yann, Theberge, Charlie, Sauvaget, Melanie, Martineau, Sandra, Gilbert, Megan, Breuils Bonnet, Sandra, Potus, Francois, Provencher, Steeve, Boucherat, Olivier, Bonnet, Sebastien

“…Abstract only Pulmonary arterial hypertension (PAH) is characterized by vascular obstruction leading to progressive elevation of pulmonary artery pressure. In…”
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Abstract 4143098: Development and characterization of an ex vivo human precision-cut lung slice (hPCLS) system for target validation for pulmonary arterial hypertension by Kim, Haejin, Jain, Dhawal, Akram, Muzaffar, Zhou, Willa, Provencher, Steeve, Lemay, Sarah-Eve, Bonnet, Sebastien, Potus, Francois, Montesinos, Monica, Lu, Min, Goodwin, Bryan

“…Abstract only Background: Translating therapeutic target biology from in vitro culture systems and animal models to humans remains a significant challenge in…”
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Abstract 4141912: Targeting NEK2 to Induce Senescence and DNA Damage in Pulmonary Arterial Hypertension by Martineau, Sandra, Yamamoto, Keiko, Bourgeois, Alice, Lemay, Sarah-Eve, Sauvaget, Melanie, Breuils Bonnet, Sandra, Potus, Francois, Provencher, Steeve, Boucherat, Olivier, Bonnet, Sebastien

“…Abstract only Introduction: Pulmonary arterial hypertension (PAH) is characterized by vasoconstriction and vascular remodeling of the distal pulmonary arteries…”
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Abstract 159: Endothelial Fatty Acid-binding Proteins Contribute To The Pathogenesis Of Pulmonary Hypertension by Dai, Zhiyu, Liu, Bin, Yi, Dan, Ramirez, Karina, Xia, Xiaomei, Rafikov, Ruslan, Dejesus, Vinicio A, Lemay, Sarah-Eve S, Bonnet, Sebastien, Boucherat, Olivier

“…Abstract only Pulmonary arterial hypertension (PAH) is a devastating disease characterized by obliterative vascular remodeling and persistent increase of…”
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Abstract 15967: Unravelling the Role of Deoxyhypusine Synthase-Mediated Hypusination of eIF5A in Pulmonary Arterial Hypertension by Lemay, Sarah-Eve, Grobs, Yann, Romanet, Charlotte, Martineau, Sandra, SALEM, MABROUKA, Shimauchi, Tsukasa, Breuils Bonnet, Sandra, Bourgeois, Alice, Theberge, Charlie, Potus, Francois, Provencher, Steeve, Bonnet, Sebastien, Boucherat, Olivier

“…Abstract only Introduction: Pulmonary Arterial Hypertension (PAH) is characterized by progressive distal pulmonary arteries (PAs) obstruction leading to heart…”
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Abstract 18286: Histone Acetyltransferase P300/CBP in Pulmonary Arterial Hypertension and Associated Right Ventricular Failure by Bourgeois, Alice, Lemay, Sarah-Eve, Grobs, Yann, Romanet, Charlotte, Theberge, Charlie, Sauvaget, Melanie, Martineau, Sandra, Breuils Bonnet, Sandra, Potus, Francois, Provencher, Steeve, Boucherat, Olivier, Bonnet, Sebastien

“…Abstract only INTRODUCTION Pulmonary arterial hypertension (PAH) is defined by increased pulmonary artery (PA) pressure and vascular remodeling, partly due to…”
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Abstract 150: Targeting The Lipogenic Enzyme ATP Citrate Lyase As A Potential Therapy Against Coronary Artery Disease by Grobs, Yann, Lemay, Sarah-Eve S, Romanet, Charlotte, Bourgeois, Alice, SALEM, MABROUKA, Martineau, Sandra, Breuils-Bonnet, Sandra, Voisine, Pierre, Potus, Francois, Provencher, Steeve, Boucherat, Olivier, Bonnet, Sebastien

“…Abstract only Introduction: Coronary artery disease (CAD) such as coronary stenosis and intra vein graft stenosis are characterized by a cancer-like…”
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Hypusine Signaling Promotes Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension by Lemay, Sarah-Eve, Grobs, Yann, Romanet, Charlotte, Martineau, Sandra, Salem, Mabrouka, Shimauchi, Tsukasa, Breuils-Bonnet, Sandra, Bourgeois, Alice, Théberge, Charlie, Pelletier, Andréanne, Potus, François, Provencher, Steeve, Bonnet, Sébastien, Boucherat, Olivier

“…The ubiquitous polyamine spermidine is essential for cell survival and proliferation. One important function of spermidine is to serve as a substrate for…”
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Abstract 10909: A Novel ATP Citrate Lyase-Dependent Metabolic-Transcriptional Axis in Pulmonary Arterial Hypertension by Bonnet, Sebastien, Romanet, Charlotte, Grobs, Yann, Lemay, Sarah-Eve, Bourgeois, Alice, Breuils-bonnet, Sandra, Martineau, Sandra, SALEM, MABROUKA, Potus, Francois, Provencher, Steeve, Boucherat, Olivier

“…INTRODUCTIONPulmonary arterial hypertension (PAH) is characterized by enhanced pulmonary artery smooth muscle (PASMC) proliferation and suppressed apoptosis…”
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Abstract 10900: Implication of the Post-Translational Formation of Hypusine in Eif5a in Pulmonary Arterial Hypertension by Lemay, Sarah-Eve, Grobs, Yann, Shimauchi, Tsukasa, Martineau, Sandra, Breuils Bonnet, Sandra, SALEM, MABROUKA, Potus, Francois, Provencher, Steeve, Bonnet, Sebastien, Boucherat, Olivier

“…Pulmonary Arterial Hypertension (PAH) is characterized by progressive pulmonary arteries (PAs) obstruction leading to heart failure and death. PA smooth muscle…”
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