Search Results - "Evdokia Dimitriadis"
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Alterations in Epithelial Cell Polarity During Endometrial Receptivity: A Systematic Review
Published in Frontiers in endocrinology (Lausanne) (27-10-2020)“…Abnormal endometrial receptivity is one of the major causes of embryo implantation failure and infertility. The plasma membrane transformation (PMT) describes…”
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The long noncoding RNA PTENP1 regulates human endometrial epithelial adhesive capacity in vitro: implications in infertility
Published in Biology of reproduction (12-02-2020)“…There is general consensus that the synchronous development of the embryo and endometrium is absolutely essential for successful implantation. Recent studies…”
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Inflammasomes-A Molecular Link for Altered Immunoregulation and Inflammation Mediated Vascular Dysfunction in Preeclampsia
Published in International journal of molecular sciences (19-02-2020)“…Preeclampsia (PE) is a pregnancy-specific multisystem disorder and is associated with maladaptation of the maternal cardiovascular system and abnormal…”
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4
Postpartum ovulation and early pregnancy in the menstruating spiny mouse, Acomys cahirinus
Published in Scientific reports (05-03-2021)“…Egyptian spiny mice are the only known species to have human-like menstruation and a postpartum ovulation. Unfortunately, no endocrine or morphological…”
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Characterization of the role for cadherin 6 in the regulation of human endometrial receptivity
Published in Reproductive biology and endocrinology (29-06-2020)“…The endometrial luminal epithelium is the first point of attachment of embryos during implantation. Failure of embryos to firmly adhere results in implantation…”
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Models for Study of Human Embryo Implantation: Choice of Cell Lines?
Published in Biology of reproduction (01-02-2010)“…Implantation failure and inadequate placental development are important contributors to infertility, recurrent miscarriage, and other pregnancy-related…”
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Infertility and the Endometrium
Published in Clinical and experimental obstetrics & gynecology (01-09-2022)“…Background: A couple’s infertility can originate from the male and/or the female. In women, the uterus provides the site where the maternal-fetal interface is…”
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Secreted MicroRNA to Predict Embryo Implantation Outcome: From Research to Clinical Diagnostic Application
Published in Frontiers in cell and developmental biology (22-09-2020)“…Embryo implantation failure is considered a leading cause of infertility and a significant bottleneck for fertilization (IVF) treatment. Confirmed factors that…”
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Tripeptidyl peptidase I promotes human endometrial epithelial cell adhesive capacity implying a role in receptivity
Published in Reproductive biology and endocrinology (14-12-2020)“…The endometrium undergoes cyclic remodelling throughout the menstrual cycle in preparation for embryo implantation which occurs in a short window during the…”
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Interleukin-11 alters placentation and causes preeclampsia features in mice
Published in Proceedings of the National Academy of Sciences - PNAS (29-12-2015)“…Preeclampsia (PE) is a pregnancy-specific disorder characterized by hypertension and proteinuria after 20 wk gestation. Abnormal extravillous trophoblast (EVT)…”
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11
Using organoids to investigate human endometrial receptivity
Published in Frontiers in endocrinology (Lausanne) (24-08-2023)“…The human endometrium is only receptive to an implanting blastocyst in the mid-secretory phase of each menstrual cycle. Such time-dependent alterations in…”
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Human Blastocyst Secreted microRNA Regulate Endometrial Epithelial Cell Adhesion
Published in EBioMedicine (01-10-2015)“…Successful embryo implantation requires synchronous development and communication between the blastocyst and the endometrium, however the mechanisms of…”
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Endometrial stromal cell miR-19b-3p release is reduced during decidualization implying a role in decidual-trophoblast cross-talk
Published in Frontiers in endocrinology (Lausanne) (16-03-2023)“…A healthy pregnancy requires successful blastocyst implantation into an adequately prepared or 'receptive' endometrium. Decidualization of uterine endometrial…”
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14
Leukemia inhibitory factor enhances endometrial stromal cell decidualization in humans and mice
Published in PloS one (23-09-2011)“…Adequate differentiation or decidualization of endometrial stromal cells (ESC) is critical for successful pregnancy in humans and rodents. Here, we…”
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Correction: Dilated Thin-Walled Blood and Lymphatic Vessels in Human Endometrium: A Potential Role for VEGF-D in Progestin-Induced Break-Through Bleeding
Published in PloS one (26-10-2021)Get full text
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Leukemia Inhibitory Factor (LIF) Inhibition during Mid-Gestation Impairs Trophoblast Invasion and Spiral Artery Remodelling during Pregnancy in Mice
Published in PloS one (19-10-2015)“…The placenta forms the interface between the maternal and fetal circulation and is critical for the establishment of a healthy pregnancy. Trophoblast cell…”
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Correction to: Subcellular localization of L-selectin ligand in the endometrium implies a novel function for pinopodes in endometrial receptivity
Published in Reproductive biology and endocrinology (23-04-2021)“…An amendment to this paper has been published and can be accessed via the original article…”
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IL11 Antagonist Inhibits Uterine Stromal Differentiation, Causing Pregnancy Failure in Mice
Published in Biology of reproduction (01-05-2009)“…Hormonal contraceptives are unsuitable for many women; thus, the development of new, nonhormonal contraceptives is of great interest. In women, uterine…”
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Infertile human endometrial organoid apical protein secretions are dysregulated and impair trophoblast progenitor cell adhesion
Published in Frontiers in endocrinology (Lausanne) (14-12-2022)“…Embryo implantation failure leads to infertility. As an important approach to regulate implantation, endometrial epithelial cells produce and secrete factors…”
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20
IL11 activates the placental inflammasome to drive preeclampsia
Published in Frontiers in immunology (24-05-2023)“…Preeclampsia is a life-threatening disorder of pregnancy unique to humans. Interleukin (IL)11 is elevated in serum from pregnancies that subsequently develop…”
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