Search Results - "Evans, Stephen J. W."
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BMI and risk of dementia in two million people over two decades: a retrospective cohort study
Published in The lancet. Diabetes & endocrinology (01-06-2015)“…Summary Background Dementia and obesity are increasingly important public health issues. Obesity in middle age has been proposed to lead to dementia in old…”
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Reporting of Noninferiority and Equivalence Randomized Trials: Extension of the CONSORT 2010 Statement
Published in JAMA : the journal of the American Medical Association (26-12-2012)“…The CONSORT (Consolidated Standards of Reporting Trials) Statement, which includes a checklist and a flow diagram, is a guideline developed to help authors…”
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Vaccine Effectiveness Studies in the Field
Published in The New England journal of medicine (12-08-2021)“…The original trials of vaccines against infection with severe acute respiratory disease coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease…”
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Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study
Published in BMJ (Online) (11-02-2021)“…To evaluate whether early initiation of prophylactic anticoagulation compared with no anticoagulation was associated with decreased risk of death among…”
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A Signal Detection Method to Detect Adverse Drug Reactions Using a Parametric Time-to-Event Model in Simulated Cohort Data
Published in Drug safety (01-07-2012)“…Background: Current quantitative signal detection methods have been primarily developed for the purpose of detecting signals from spontaneous reports. These…”
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6
The Prevalence of Huntington's Disease
Published in Neuroepidemiology (01-03-2016)“…Reviews of the epidemiology of Huntington's disease (HD) suggest that its worldwide prevalence varies widely. This review was undertaken to confirm these…”
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Prevalence of adult Huntington's disease in the UK based on diagnoses recorded in general practice records
Published in Journal of neurology, neurosurgery and psychiatry (01-10-2013)“…Background and purpose The prevalence of Huntington's disease (HD) in the UK is uncertain. Recently, it has been suggested that the prevalence may be…”
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8
Type I interferon causes thrombotic microangiopathy by a dose-dependent toxic effect on the microvasculature
Published in Blood (15-12-2016)“…Many drugs have been reported to cause thrombotic microangiopathy (TMA), yet evidence supporting a direct association is often weak. In particular, TMA has…”
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General determination of causation between Covid-19 vaccines and possible adverse events
Published in Vaccine (05-03-2021)“…•Covid-19 vaccine safety problems may be identified only after widespread use of the vaccine.•Rapid introduction across many different countries may lead to…”
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10
Latest trends in ADHD drug prescribing patterns in children in the UK: prevalence, incidence and persistence
Published in BMJ open (13-06-2016)“…ObjectivesTo investigate attention deficit and hyperactivity disorder (ADHD) drug prescribing in children under 16 years old in the UK between 1992 and…”
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Identifying Adverse Events of Vaccines Using a Bayesian Method of Medically Guided Information Sharing
Published in Drug safety (2012)“…Background: The detection of adverse events following immunization (AEFI) fundamentally depends on how these events are classified. Standard methods impose a…”
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Safety profile of rubella vaccine administered to pregnant women: A systematic review of pregnancy related adverse events following immunisation, including congenital rubella syndrome and congenital rubella infection in the foetus or infant
Published in Vaccine (29-01-2020)“…•The safety of inadvertent rubella vaccination in pregnancy is assessed.•Evidence is limited, often with no unvaccinated comparison group in registers.•No…”
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Modelling hepatitis C infection acquired from blood transfusions in the UK between 1970 and 1991 for the Infected Blood Inquiry
Published in Royal Society open science (01-06-2024)“…The Statistics Expert Group was convened at the request of the Infected Blood Inquiry to provide estimates of the number of infections and deaths from…”
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14
Better Reporting of harms in randomized trials: An extension of the CONSORT statement
Published in Annals of internal medicine (16-11-2004)“…In response to overwhelming evidence and the consequences of poor-quality reporting of randomized, controlled trials (RCTs), many medical journals and…”
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15
Lithium prescribing during pregnancy: a UK primary care database study
Published in PloS one (20-03-2015)“…Women taking lithium must decide whether to continue the medication if they conceive or plan to conceive. Little is known about the extent of prescribing of…”
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Association between warfarin and COVID-19-related outcomes compared with direct oral anticoagulants: population-based cohort study
Published in Journal of hematology and oncology (19-10-2021)“…Thromboembolism has been reported as a consequence of severe COVID-19. Although warfarin is a commonly used anticoagulant, it acts by antagonising vitamin K,…”
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Human Papilloma Virus Immunization in Adolescent and Young Adults: A Cohort Study to Illustrate What Events Might be Mistaken for Adverse Reactions
Published in The Pediatric infectious disease journal (01-11-2007)“…BACKGROUND:The large-scale implementation of human papilloma virus (HPV) immunization will be followed by cases of autoimmune diseases occurring in temporal…”
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18
Design choices for observational studies of the effect of exposure on disease incidence
Published in BMJ open (09-12-2019)“…The purpose of this paper is to help readers choose an appropriate observational study design for measuring an association between an exposure and disease…”
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Factors associated with COVID-19-related death using OpenSAFELY
Published in Nature (London) (20-08-2020)“…Coronavirus disease 2019 (COVID-19) has rapidly affected mortality worldwide 1 . There is unprecedented urgency to understand who is most at risk of severe…”
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Identifying Patterns of Clinical Interest in Clinicians' Treatment Preferences: Hypothesis-free Data Science Approach to Prioritizing Prescribing Outliers for Clinical Review
Published in JMIR medical informatics (20-12-2022)“…Data analysis is used to identify signals suggestive of variation in treatment choice or clinical outcome. Analyses to date have generally focused on a…”
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