Search Results - "Evans, Richard P. T."

The single cell transcriptional landscape of esophageal adenocarcinoma and its modulation by neoadjuvant chemotherapy by Croft, Wayne, Evans, Richard P T, Pearce, Hayden, Elshafie, Mona, Griffiths, Ewen A, Moss, Paul

“…Immune checkpoint blockade has recently proven effective in subsets of patients with esophageal adenocarcinoma (EAC) but little is known regarding the EAC…”
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Perioperative outcomes after laparoscopic cholecystectomy in elderly patients: a systematic review and meta-analysis by Kamarajah, Sivesh K., Karri, Santhosh, Bundred, James R., Evans, Richard P. T., Lin, Aaron, Kew, Tania, Ekeozor, Chinenye, Powell, Susan L., Singh, Pritam, Griffiths, Ewen A.

“…Background Laparoscopic cholecystectomy is increasingly performed in an ever ageing population; however, the risks are poorly quantified. The study aims to…”
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Peri-operative Outcomes and Survival Following Palliative Gastrectomy for Gastric Cancer: a Systematic Review and Meta-analysis by Cowling, Joseph, Gorman, Bethany, Riaz, Afrah, Bundred, James R., Kamarajah, Sivesh K., Evans, Richard P. T., Singh, Pritam, Griffiths, Ewen A.

“…Background Many patients with gastric cancer present with late stage disease. Palliative gastrectomy remains a contentious intervention aiming to debulk tumour…”
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Hepatic and Intra-abdominal Tuberculosis: 2016 Update by Evans, Richard P. T., Mourad, Moustafa Mabrouk, Dvorkin, Lee, Bramhall, Simon R.

“…Mycobacterium tuberculosis (TB) infection affects nearly 10 million people a year and causes 1.5 million deaths. TB is common in the immunosuppressed…”
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Evolving management of metaplasia and dysplasia in Barrett’s epithelium by Evans, Richard P T, Mourad, Moustafa Mabrouk, Fisher, Simon G, Bramhall, Simon R

“…Oesophageal cancer affects more than 450000 people worldwide and despite continued medical advancements the incidence of oesophageal cancer is increasing…”
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Colonic Perforation: A Medical Complication by Parsons, Christopher, Chan, Elizabeth, Evans, Richard P T, Mourad, Moustafa Mabrouk, Leung, Edmund

“…Hypothyroidism is a common comorbidity that on acute presentation is often overlooked. It can be an easily managed condition; however non-compliance can have…”
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Risk factors and outcomes associated with anastomotic leaks following esophagectomy: a systematic review and meta-analysis by Kamarajah, Sivesh K, Lin, Aaron, Tharmaraja, Thahesh, Bharwada, Yashvi, Bundred, James R, Nepogodiev, Dmitri, Evans, Richard P T, Singh, Pritam, Griffiths, Ewen A

“…Summary Anastomotic leaks (AL) are a major complication after esophagectomy. This meta-analysis aimed to determine identify risks factors for AL (preoperative,…”
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Acute Kidney Injury After Esophageal Cancer Surgery: Incidence, Risk Factors, and Impact on Oncologic Outcomes by Murphy, Conor F., Dunne, Talulla, Elliott, Jessie A., Kamarajah, Sivesh K., Leighton, James, Evans, Richard P. T., Bundred, James, King, Sinead, Ravi, Narayanasamy, Donohoe, Claire L., Griffin, S. Michael, Griffiths, Ewen A., Phillips, Alexander W., Reynolds, John V.

“…OBJECTIVE:To determine the incidence, risk factors, and consequences of AKI in patients undergoing surgery for esophageal cancer. SUMMARY OF BACKGROUND…”
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Current and Future Immunotherapy-Based Treatments for Oesophageal Cancers by To, Natalie, Evans, Richard P T, Pearce, Hayden, Kamarajah, Sivesh K, Moss, Paul, Griffiths, Ewen A

“…Oesophageal cancer is a disease that causes significant morbidity and mortality worldwide, and the prognosis of this condition has hardly improved in the past…”
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Response to the Comment on “Acute Kidney Injury After Esophageal Cancer Surgery: Incidence, Risk Factors, and Impact on Oncologic Outcomes” by Murphy, Conor F., Dunne, Talulla, Elliott, Jessie A., Kamarajah, Sivesh K., Leighton, James, Evans, Richard P. T., Bundred, James, King, Sinead, Ravi, Narayanasamy, Donohoe, Claire L., Griffin, S. Michael, Griffiths, Ewen A., Phillips, Alexander W., Reynolds, John V.

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Impact of neoadjuvant chemotherapy on nodal regression and survival in oesophageal adenocarcinoma by Evans, Richard PT, Kamarajah, Sivesh K., Kunene, Victoria, Zardo, Davide, Elshafie, Mona, Griffiths, Ewen A.

“…The prognostic value of lymph node regression (LNR) following neoadjuvant chemotherapy (nCT) for oesophageal and gastro-oeosphageal adenocarcinoma remains…”
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Meta-analysis of prognostic factors of overall survival in patients undergoing oesophagectomy for oesophageal cancer by Kamarajah, Sivesh K, Marson, Ella J, Zhou, Dengyi, Wyn-Griffiths, Freddie, Lin, Aaron, Evans, Richard P T, Bundred, James R, Singh, Pritam, Griffiths, Ewen A

“…Currently, the American Joint Commission on Cancer (AJCC) staging system is used for prognostication for oesophageal cancer. However, several prognostically…”
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Elderly patients have increased perioperative morbidity and mortality from oesophagectomy for oesophageal cancer: A systematic review and meta-analysis by Kamarajah, Sivesh K., Gujjuri, Rohan R., Elhadi, Muhammed, Umar, Hamza, Bundred, James R., Subramanya, Manjunath S., Evans, Richard PT, Powell, Susan L., Griffiths, Ewen A.

“…Although oesophagectomy remains technically challenging and associated with high morbidity and mortality, it is now increasingly performed in an ever-ageing…”
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Pancreatitis: Preventing catastrophic haemorrhage by Evans, Richard Pt, Mourad, Moustafa Mabrouk, Pall, Gunraj, Fisher, Simon G, Bramhall, Simon R

“…Pancreatitis represents nearly 3% of acute admissions to general surgery in United Kingdom hospitals and has a mortality of around 1%-7% which increases to…”
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Definitive chemoradiotherapy versus neoadjuvant chemoradiotherapy followed by radical surgery for locally advanced oesophageal squamous cell carcinoma: meta-analysis by Kamarajah, Sivesh K, Evans, Richard P T, Griffiths, Ewen A, Gossage, James A, Pucher, Philip H

“…The literature lacks robust evidence comparing definitive chemoradiotherapy (dCRT) with neoadjuvant chemoradiotherapy and surgery (nCRS) for oesophageal…”
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Vascular access in the Obese: Superficialisation of Native Radio-Cephalic and Brachio-Cephalic Fistulae by Evans, Richard P.T., Meecham, Lewis, Buxton, Pauline, Jafferbhoy, Sadaf, Legge, Jocelyn, Papp, Laszlo, Ehsan, Omer, Pherwani, Arun D.

“…Purpose The Department of Health estimates that currently in the UK, 61.3% of the population are overweight or obese (BMI >25 kg/m2). Fistulae in the obese…”
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Pathologic Lymph Node Regression After Neoadjuvant Chemotherapy Predicts Recurrence and Survival in Esophageal Adenocarcinoma: A Multicenter Study in the United Kingdom by Moore, Jonathan L, Green, Michael, Santaolalla, Aida, Deere, Harriet, Evans, Richard P T, Elshafie, Mona, Lavery, Anita, McManus, Damian T, McGuigan, Andrew, Douglas, Rosalie, Horne, Joanne, Walker, Robert, Mir, Hira, Terlizzo, Monica, Kamarajah, Sivesh K, Van Hemelrijck, Mieke, Maisey, Nick, Sita-Lumsden, Ailsa, Ngan, Sarah, Kelly, Mark, Baker, Cara R, Kumar, Sacheen, Lagergren, Jesper, Allum, William H, Gossage, James A, Griffiths, Ewen A, Grabsch, Heike I, Turkington, Richard C, Underwood, Tim J, Smyth, Elizabeth C, Fitzgerald, Rebecca C, Cunningham, David, Davies, Andrew R

“…There is limited evidence regarding the prognostic effects of pathologic lymph node (LN) regression after neoadjuvant chemotherapy for esophageal…”
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O64 META-ANALYSIS OF PROGNOSTIC FACTORS FOR OVERALL SURVIVAL IN PATIENTS UNDERGOING OESOPHAGECTOMY FOR OESOPHAGEAL CANCERS by Kamarajah, Sivesh K, Marson, Ella J, Zhou, Dengyi, Wyn-Griffiths, Freddie, Richard P T, Evans, Bundred, James R, Singh, Pritam, Griffiths, Ewen A

“…Abstract Aims The objective of this meta-analysis was to assess statistically the impact of patient-level, operative, and tumour characteristics on overall…”
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P22 Are Elderly Patients at Increased Perioperative Morbidity and Mortality from Oesophagectomy for Oesophageal Cancer? A Systematic Mapping Review and Meta-Analysis by Gujjuri, Rohan R, Elhadi, Muhammed, Umar, Hamza, Subramanya, Manjunath S, Evans, Richard P T, Kamarajah, Sivesh K, Griffiths, Ewen A

“…Abstract Introduction Oesophagectomy is being increasingly performed in an ageing population that is observing a concomitant growth in the life expectancy…”
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517. INTERNATIONAL CONSENSUS AND CLINICAL CARE ALGORITHM FOR THE DIAGNOSIS AND TREATMENT OF ANASTOMOTIC LEAK AFTER ESOPHAGECTOMY by Stuart, Sanne K, Lemmens, Jobbe, Nieuwenhuijzen, Grard AP, Evans, Richard PT, Kamarajah, Sivesh K, Wijnhoven, Bas, Wong, Ian YH, Griffiths, Ewen A, Ubels, Sander, Klarenbeek, Bastiaan R, Rosman, Camiel

“…Abstract Background Anastomotic leak (AL) is a common and severe complication after esophagectomy. Guidelines for the management of AL are lacking due to…”
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