Search Results - "Evans, R. J."

Photosynthetic acclimation of plants to growth irradiance: the relative importance of specific leaf area and nitrogen partitioning in maximizing carbon gain by Evans, J. R., Poorter, H.

“…Changes in specific leaf area (SLA, projected leaf area per unit leaf dry mass) and nitrogen partitioning between proteins within leaves occur during the…”
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Proof of concept trial of tanezumab for the treatment of symptoms associated with interstitial cystitis by Evans, R J, Moldwin, R M, Cossons, N, Darekar, A, Mills, I W, Scholfield, D

“…In this randomized, double-blind, placebo controlled phase 2 study we investigated tanezumab, a humanized monoclonal antibody that specifically inhibits nerve…”
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A Pioneer in Context: T R Miles and the Bangor Dyslexia Unit by Evans, R. J. W.

“…T R ('Tim') Miles (1923-2008) was one of the most important pioneers of dyslexia research and treatment in the UK. He worked with dyslexics from the time of…”
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Molecular basis of selective antagonism of the P2X1 receptor for ATP by NF449 and suramin: contribution of basic amino acids in the cysteine‐rich loop by El‐Ajouz, S, Ray, D, Allsopp, RC, Evans, RJ

“…BACKGROUND AND PURPOSE The cysteine‐rich head region, which is adjacent to the proposed ATP‐binding pocket in the extracellular ligand‐binding loop of P2X…”
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The disappearance of relict permafrost in boreal north America: Effects on peatland carbon storage and fluxes by TURETSKY, M. R., WIEDER, R. K., VITT, D. H., EVANS, R. J., SCOTT, K. D.

“…Boreal peatlands in Canada have harbored relict permafrost since the Little Ice Age due to the strong insulating properties of peat. Ongoing climate change has…”
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Exploiting inflammation for therapeutic gain in pancreatic cancer by Steele, C W, Jamieson, N B, Evans, T R J, McKay, C J, Sansom, O J, Morton, J P, Carter, C R

“…Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy associated with <5% 5-year survival, in which standard chemotherapeutics have limited…”
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Short-term outcomes after perinatal hypoxic ischemic encephalopathy: a report from the Children’s Hospitals Neonatal Consortium HIE focus group by Massaro, A N, Murthy, K, Zaniletti, I, Cook, N, DiGeronimo, R, Dizon, M, Hamrick, S E G, McKay, V J, Natarajan, G, Rao, R, Smith, D, Telesco, R, Wadhawan, R, Asselin, J M, Durand, D J, Evans, J R, Dykes, F, Reber, K M, Padula, M A, Pallotto, E K, Short, B L, Mathur, A M

“…Objective: To characterize infants affected with perinatal hypoxic ischemic encephalopathy (HIE) who were referred to regional neonatal intensive care units…”
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The surface of articular cartilage contains a progenitor cell population by Dowthwaite, Gary P, Bishop, Joanna C, Redman, Samantha N, Khan, Ilyas M, Rooney, Paul, Evans, Darrell J R, Haughton, Laura, Bayram, Zubeyde, Boyer, Sam, Thomson, Brian, Wolfe, Michael S, Archer, Charles W

“…It is becoming increasingly apparent that articular cartilage growth is achieved by apposition from the articular surface. For such a mechanism to occur, a…”
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Assessing Anatomy Education: A Perspective from Design by Roxburgh, Mark, Evans, Darrell J.R.

“…Medical and healthcare practice is likely to see fundamental changes in the future that will require a different approach to the way in which we educate,…”
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Orthosteric and allosteric binding sites of P2X receptors by Evans, R. J

“…P2X receptors for ATP comprise a distinct family of ligand gated ion channels with a range of properties. They have been shown to be involved in a variety of…”
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Early constipation predicts faster dementia onset in Parkinson’s disease by Camacho, M., Macleod, A. D., Maple-Grødem, J., Evans, J. R., Breen, D. P., Cummins, G., Wijeyekoon, R. S., Greenland, J. C., Alves, G., Tysnes, O. B., Lawson, R. A., Barker, R. A., Williams-Gray, C. H.

“…Constipation is a common but not a universal feature in early PD, suggesting that gut involvement is heterogeneous and may be part of a distinct PD subtype…”
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Motivating student learning using a formative assessment journey by Evans, Darrell J. R., Zeun, Paul, Stanier, Robert A.

“…Providing formative assessment opportunities has been recognised as a significant benefit to student learning. The outcome of any formative assessment should…”
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Profiles of light absorption and chlorophyll within spinach leaves from chlorophyll fluorescence by Vogelmann, T. C., Evans, J. R.

“…Chlorophyll fluorescence was used to estimate profiles of absorbed light within chlorophyll solutions and leaves. For chlorophyll solutions, the intensity of…”
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Revisiting Hume-Rothery’s Rules with artificial neural networks by Zhang, Y.M., Yang, S., Evans, J.R.G.

“…Hume-Rothery’s breadth of knowledge combined with a quest for generality gave him insights into the reasons for solubility in metallic systems that have become…”
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Shape Changes during the Drying of Droplets of Suspensions by Zhang, Y, Yang, S, Chen, L, Evans, J. R. G

“…During drying of droplets of suspensions, several flow regimes contribute to the radial flow of powder to the periphery to leave a pile-up of powder at the…”
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P2X receptor expression in mouse urinary bladder and the requirement of P2X1 receptors for functional P2X receptor responses in the mouse urinary bladder smooth muscle by Vial, C, Evans, R J

“…We have used subtype selective P2X receptor antibodies to determine the expression of P2X1–7 receptor subunits in the mouse urinary bladder. In addition we…”
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Immune checkpoint inhibitors: new strategies to checkmate cancer by Wilson, R. A. M., Evans, T. R. J., Fraser, A. R., Nibbs, R. J. B.

“…Summary Immune checkpoint inhibitors (ICIs) targeting cytotoxic T lymphocyte‐associated protein‐4 (CTLA‐4) or programmed cell death protein 1 (PD‐1) receptors…”
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Seventy ways to make ceramics by Evans, J.R.G.

“…This is an attempt to classify ceramic manufacturing processes in such a way that the connections to related operations in other industries and to the ancient…”
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Phase 1 study of the ATR inhibitor berzosertib (formerly M6620, VX-970) combined with gemcitabine ± cisplatin in patients with advanced solid tumours by Middleton, Mark R., Dean, Emma, Evans, Thomas R. J., Shapiro, Geoffrey I., Pollard, John, Hendriks, Bart S., Falk, Martin, Diaz-Padilla, Ivan, Plummer, Ruth

“…Background Berzosertib (formerly M6620, VX-970) is a highly potent and selective, first-in-class inhibitor of ataxia telangiectasia and Rad3-related protein…”
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A first-in-human phase I and pharmacokinetic study of CP-4126 (CO-101), a nucleoside analogue, in patients with advanced solid tumours by Venugopal, B., Awada, A., Evans, T. R. J., Dueland, S., Hendlisz, A., Rasch, W., Hernes, K., Hagen, S., Aamdal, S.

“…Background CP-4126 (gemcitabine elaidate, previously CO-101) is a lipid–drug conjugate of gemcitabine designed to circumvent human equilibrative nucleoside…”
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