Search Results - "Evans, Paul A S"

Rearrangement of the BCL6 locus at 3q27 is an independent poor prognostic factor in nodal diffuse large B‐cell lymphoma by Barrans, Sharon L., O'Connor, Sheila J. M., Evans, Paul A. S., Davies, Faith E., Owen, Roger G., Haynes, Andrew P., Morgan, Gareth J., Jack, Andrew S.

“…Diffuse large B‐cell lymphomas (DLBCL) are a heterogeneous group of tumours, varying in clinical features, immunophenotype and cytogenetics. The aim of this…”
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Monoclonal B lymphocytes with the characteristics of “indolent” chronic lymphocytic leukemia are present in 3.5% of adults with normal blood counts by Rawstron, Andy C., Green, Michael J., Kuzmicki, Anita, Kennedy, Ben, Fenton, James A.L., Evans, Paul A.S., O'Connor, Sheila J.M., Richards, Stephen J., Morgan, Gareth J., Jack, Andrew S., Hillmen, Peter

“…Molecular and cellular markers associated with malignant disease are frequently identified in healthy individuals. The relationship between these markers and…”
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The t(14;18) Is Associated with Germinal Center-derived Diffuse Large B-Cell Lymphoma and Is a Strong Predictor of Outcome by BARRANS, Sharon L, EVANS, Paul A. S, O'CONNOR, Sheila J. M, KENDALL, S. Jane, OWEN, Roger G, HAYNES, Andrew P, MORGAN, Gareth J, JACK, Andrew S

“…The t(14;18) is present in a significant proportion of diffuse large B-cell lymphomas (DLBCLs), however, the prognostic effect of the translocation and the…”
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Minimal residual disease is an independent predictor for 10-year survival in CLL by Kwok, Marwan, Rawstron, Andy C., Varghese, Abraham, Evans, Paul A.S., O'Connor, Sheila J.M., Doughty, Chi, Newton, Darren J., Moreton, Paul, Hillmen, Peter

“…Minimal residual disease (MRD) negativity, defined as <1 chronic lymphocytic leukemia (CLL) cell detectable per 10 000 leukocytes, has been shown to…”
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The impact of attaining a minimal disease state after high‐dose melphalan and autologous transplantation for multiple myeloma by Davies, Faith E., Forsyth, Peter D., Rawstron, Andrew C., Owen, Roger G., Pratt, Guy, Evans, Paul A. S., Richards, Stephen J., Drayson, Mark, Smith, Graeme M., Selby, Peter J., Child, J. Anthony, Morgan, Gareth J.

“…Initial studies with high‐dose therapy (HDT) in myeloma suggest some beneficial effects of attaining a complete response (CR); however, the effect on survival…”
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Consensus on BCR‐ABL1 reporting in chronic myeloid leukaemia in the UK by Cross, Nicholas C. P., White, Helen E., Evans, Paul A. S., Hancock, Jeremy, Copland, Mhairi, Milojkovic, Dragana, Mason, Joanne, Craine, Sandra, Mead, Adam J.

“…Summary For patients with chronic myeloid leukaemia (CML), treatment guidelines recommend monitoring response to treatment with tyrosine kinase inhibitors…”
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Optimising care for UK patients with acute myeloid leukaemia by Pagliuca, Antonio, Khwaja, Asim, Dillon, Richard, Evans, Paul AS, Mohite, Unmesh

“…This article has been commissioned and funded by Astellas Pharma Ltd. Astellas Pharma Ltd also had editorial input in the writing of this article.   Job code…”
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Quantitation of minimal disease levels in chronic lymphocytic leukemia using a sensitive flow cytometric assay improves the prediction of outcome and can be used to optimize therapy by Rawstron, Andy C., Kennedy, Ben, Evans, Paul A.S., Davies, Faith E., Richards, Stephen J., Haynes, Andy P., Russell, Nigel H., Hale, Geoff, Morgan, Gareth J., Jack, Andrew S., Hillmen, Peter

“…Previous studies have suggested that the level of residual disease at the end of therapy predicts outcome in chronic lymphocytic leukemia (CLL). However,…”
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Indolent mantle-cell lymphoma: immunoglobulin variable region heavy chain sequence analysis reveals evidence of disease 10 years prior to symptomatic clinical presentation by Rule, Simon A J, Poplar, Sarah, Evans, Paul A S, O'Connor, Sheila J M, Owen, Roger G

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A New and Simple TRG Multiplex PCR Assay for Assessment of T‐cell Clonality: A Comparative Study from the EuroClonality Consortium by Armand, Marine, Derrieux, Coralie, Beldjord, Kheira, Wabeke, Tamara, Lenze, Dido, Boone, Elke, Bruggemann, Monika, Evans, Paul A.S., Gameiro, Paula, Hummel, Michael, Villarese, Patrick, Groenen, Patricia J.T.A., Langerak, Anton W., Macintyre, Elizabeth A., Davi, Frederic

“…Supplemental Digital Content is available in the text T‐cell Receptor Gamma (TRG) rearrangements are commonly used to detect clonal lymphoproliferations in…”
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Monoclonal B-cell lymphocytosis in a hospital-based UK population and a rural Ugandan population: a cross-sectional study by Rawstron, Andy C, Ssemaganda, Aloysius, de Tute, Ruth, Doughty, Chi, Newton, Darren, Vardi, Anna, Evans, Paul A S, Stamatopoulos, Kostas, Owen, Roger G, Lightfoot, Tracy, Wakeham, Katie, Karabarinde, Alex, Asiki, Gershim, Newton, Robert

“…Reported incidence of B-cell malignancies shows substantial geographical variation, being more common in the Americas and Europe than in Africa. This variation…”
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Development of EBV-associated diffuse large B-cell lymphoma in Waldenström macroglobulinemia and mantle cell lymphoma by Varghese, Abraham M., Sayala, Hazem, Evans, Paul A. S., O'Connor, Sheila J. M., Patmore, Russell, Hillmen, Peter, Owen, Roger G.

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Targeted Sequencing Predicts the Development of Myeloid Malignancies and Clinical Outcome in Patients with Unexplained Cytopenia by Cargo, Catherine, Bolton, Kelly, Beinortas, Tumas, Glover, Paul, Short, Michael, Smith, Alexandra, Taylor, Jan, Evans, Paul A S, Papaemmanuil, Elli, Crouch, Simon

“…The high frequency of somatic mutations in myelodysplastic syndromes (MDS) provides an additional biomarker modality for MDS diagnosis. This has significant…”
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THE SIGNIFICANCE OF B-CELL CLONALITY IN GASTRIC LYMPHOID INFILTRATES by CALVERT, RICHARD J., EVANS, PAUL A. S., RANDERSON, JULIETTE A., JACK, ANDREW S., MORGAN, GARETH J., DIXON, MICHAEL F.

“…The significance of the demonstration of a clonal B‐cell population in gastric lymphoid infiltrates was investigated by analysis of immunoglobulin heavy chain…”
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Cdx Report Program: Heterogeneity Revealed in Current Reporting Practices for Hemato-Oncology Companion Diagnostic (CDx) Markers in Multiple Countries by Delic, Sabit, Blombery, Piers, Calasanz, María José, Chabot-Richards, Devon S., Colomer, Dolors, Porta, Matteo G Della, Evans, Paul A S, Haferlach, Torsten, Mason, Joanne, Patel, Jay L, Stevenson, William S., Thiede, Christian, Voso, Maria Teresa, Clark, Jordan

“…Introduction: In the current era of precision medicine, CDx tests have become the basis for optimal patient care and targeted treatment. While technical…”
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Consensus on BCR ‐ ABL 1 reporting in chronic myeloid leukaemia in the UK by Cross, Nicholas C. P., White, Helen E., Evans, Paul A. S., Hancock, Jeremy, Copland, Mhairi, Milojkovic, Dragana, Mason, Joanne, Craine, Sandra, Mead, Adam J.

“…For patients with chronic myeloid leukaemia ( CML ), treatment guidelines recommend monitoring response to treatment with tyrosine kinase inhibitors ( TKI s)…”
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Immunoglobulin Heavy Chain Sequence Analysis in Waldenström's Macroglobulinemia and Immunoglobulin M Monoclonal Gammopathy of Undetermined Significance by Rollett, Rebecca A., Wilkinson, Elizabeth J., Gonzalez, David, Fenton, James A.L., Short, Michael A., Evans, Paul A.S., Rawstron, Andy C., Owen, Roger G.

“…In this study, we used IGH sequence analysis to assess the maturational status of Waldenström's (WM) macroglobulinemia and its putative precursor…”
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Stem-cell transplantation in non-Hodgkinʼs lymphoma: improving outcome by Gianni, Alessandro M, Berinstein, Neil L, Evans, Paul AS, López-Guillermo, Armando, Solano, Carlos

“…High-dose therapy with stem-cell transplantation is a potentially curative therapy for younger patients with relapsed aggressive non-Hodgkinʼs lymphoma (NHL)…”
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The Detection of t(14;18) in Archival Lymph Nodes: Development of a Fluorescence in Situ Hybridization (FISH)-Based Method and Evaluation by Comparison with Polymerase Chain Reaction by Barrans, Sharon L, Evans, Paul A.S, O'Connor, Sheila J.M, Owen, Roger G, Morgan, Gareth J, Jack, Andrew S

“…Fluorescence in situ hybridization (FISH) has been used to demonstrate the t(14;18) in up to 100% of follicular lymphoma (FL) cases, however, there is little…”
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Fluorescent IgH fingerprinting to assess minimal residual disease in childhood B-lineage ALL by Evans, Paul A S, Owen, Roger G

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