Search Results - "Evans, P"
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Catalytic Enantioselective Alkylation of Prochiral Enolates
Published in Chemical reviews (11-08-2021)“…The asymmetric alkylation of enolates is a particularly versatile method for the construction of α-stereogenic carbonyl motifs, which are ubiquitous in…”
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Asymmetric Rhodium-Catalyzed Allylic Substitution Reactions: Discovery, Development and Applications to Target-Directed Synthesis
Published in Journal of organic chemistry (05-10-2018)“…The transition metal-catalyzed allylic substitution reaction is a particularly versatile method for the construction of carbon–carbon and carbon–heteroatom…”
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3
Anthropogenic climate change has driven over 5 million km2 of drylands towards desertification
Published in Nature communications (31-07-2020)“…Drylands cover 41% of the earth’s land surface and include 45% of the world’s agricultural land. These regions are among the most vulnerable ecosystems to…”
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Preventing polyspermy in mammalian eggs—Contributions of the membrane block and other mechanisms
Published in Molecular reproduction and development (01-03-2020)“…The egg's blocks to polyspermy (fertilization of an egg by more than one sperm) were originally identified in marine and aquatic species with external…”
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21st century climate change in the Middle East
Published in Climatic change (01-02-2009)“…This study examined the performance and future predictions for the Middle East produced by 18 global climate models participating in the Intergovernmental…”
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Intramolecular Rhodium-Catalyzed [(3+2+2)] Carbocyclization Reactions with Dienylidenecyclopropanes: A Concise and Stereoselective Total Synthesis of the Sesquiterpene (+)-Zizaene
Published in Journal of the American Chemical Society (22-02-2023)“…The development of an intramolecular rhodium-catalyzed [(3+2+2)] carbocyclization reaction of alkylidenecyclopropanes (ACPs) tethered to 1,4- and 1,5-skipped…”
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A Concise, Efficient and Scalable Total Synthesis of Thapsigargin and Nortrilobolide from (R)‑(−)-Carvone
Published in Journal of the American Chemical Society (03-05-2017)“…A concise, efficient and scalable synthesis of thapsigargin and nortrilobolide from commercially available (R)-(−)-carvone was developed. Our synthetic…”
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Resilience, ecology and adaptation in the experimental city
Published in Transactions - Institute of British Geographers (1965) (01-04-2011)“…In the face of global urbanisation and climate change, scientists are increasingly using cities to experiment with more resilient forms of urban…”
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The incidence of acute pancreatitis: impact of social deprivation, alcohol consumption, seasonal and demographic factors
Published in Alimentary pharmacology & therapeutics (01-09-2013)“…Summary Background The incidence of acute pancreatitis has increased sharply in many European countries and the USA in recent years. Aim To establish trends in…”
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Proton radiography and tomography with application to proton therapy
Published in British journal of radiology (01-09-2015)“…Proton radiography and tomography have long promised benefit for proton therapy. Their first suggestion was in the early 1960s and the first published proton…”
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2SXPS: An Improved and Expanded Swift X-Ray Telescope Point-source Catalog
Published in The Astrophysical journal (01-04-2020)“…We present the 2SXPS (Swift-XRT Point Source) catalog, containing 206,335 point sources detected by the Swift X-ray Telescope (XRT) in the 0.3–10 keV energy…”
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Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection
Published in Science translational medicine (23-03-2022)“…The waning efficacy of SARS-CoV-2 vaccines, combined with the continued emergence of variants resistant to vaccine-induced immunity, has reignited debate over…”
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COVID-19 and violence: a research call to action
Published in BMC women's health (10-11-2020)“…COVID-19 related guidelines and movement restrictions are designed to protect the public's health and reduce disease transmission; yet, COVID-19 related…”
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14
Future increases in extreme precipitation exceed observed scaling rates
Published in Nature climate change (01-02-2017)“…Extreme rainfall is predicted to increase with warming; however observations show differing rates of change. This study shows rainfall-associated cooling…”
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Stereoselective transition metal-catalysed higher-order carbocyclisation reactions
Published in Chemical Society reviews (01-08-2010)“…Transition metal-catalysed higher-order carbocyclisation reactions represent an important class of reactions due to their ability to construct complex…”
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Global hotspots for the occurrence of compound events
Published in Nature communications (24-11-2020)“…Compound events (CEs) are weather and climate events that result from multiple hazards or drivers with the potential to cause severe socio-economic impacts…”
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A Multimessenger Picture of the Flaring Blazar TXS 0506+056: Implications for High-energy Neutrino Emission and Cosmic-Ray Acceleration
Published in The Astrophysical journal (01-09-2018)“…Detection of the IceCube-170922A neutrino coincident with the flaring blazar TXS 0506+056, the first and only ∼3 high-energy neutrino source association to…”
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Climate Change Increases the Potential for Extreme Wildfires
Published in Geophysical research letters (28-07-2019)“…Pyrocumulonimbus (pyroCb) wildfires cause devastation in many regions globally. Given that fire‐atmosphere coupling is associated with pyroCbs, future changes…”
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Enantioselective Rhodium-Catalyzed Allylic Alkylation of Prochiral α,α-Disubstituted Aldehyde Enolates for the Construction of Acyclic Quaternary Stereogenic Centers
Published in Journal of the American Chemical Society (30-11-2016)“…A highly enantioselective rhodium-catalyzed allylic alkylation of prochiral α,α-disubstituted aldehyde enolates with allyl benzoate is described. This protocol…”
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Understanding the Mechanisms of Androgen Deprivation Resistance in Prostate Cancer at the Molecular Level
Published in European urology (01-03-2015)“…Abstract Context Various molecular mechanisms play a role in the development of resistance to androgen deprivation therapy in castration-resistant prostate…”
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