Search Results - "Evans, Myron K."

Ybx1 fine-tunes PRC2 activities to control embryonic brain development by Evans, Myron K., Matsui, Yurika, Xu, Beisi, Willis, Catherine, Loome, Jennifer, Milburn, Luis, Fan, Yiping, Pagala, Vishwajeeth, Peng, Jamy C.

“…Chromatin modifiers affect spatiotemporal gene expression programs that underlie organismal development. The Polycomb repressive complex 2 (PRC2) is a crucial…”
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Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer by Allensworth, Jennifer L., Evans, Myron K., Bertucci, François, Aldrich, Amy J., Festa, Richard A., Finetti, Pascal, Ueno, Naoto T., Safi, Rachid, McDonnell, Donald P., Thiele, Dennis J., Van Laere, Steven, Devi, Gayathri R.

“…Cancer cells often have increased levels of reactive oxygen species (ROS); however, acquisition of redox adaptive mechanisms allows for evasion of ROS-mediated…”
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Author Correction: Ybx1 fine-tunes PRC2 activities to control embryonic brain development by Evans, Myron K., Matsui, Yurika, Xu, Beisi, Willis, Catherine, Loome, Jennifer, Milburn, Luis, Fan, Yiping, Pagala, Vishwajeeth, Peng, Jamy C.

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Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity by Langdon, Casey G., Gadek, Katherine E., Garcia, Matthew R., Evans, Myron K., Reed, Kristin B., Bush, Madeline, Hanna, Jason A., Drummond, Catherine J., Maguire, Matthew C., Leavey, Patrick J., Finkelstein, David, Jin, Hongjian, Schreiner, Patrick A., Rehg, Jerold E., Hatley, Mark E.

“…PTEN promoter hypermethylation is nearly universal and PTEN copy number loss occurs in ~25% of fusion-negative rhabdomyosarcoma (FN-RMS). Here we show Pten…”
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Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma by Noll, Alyssa, Myers, Carrie, Biery, Matthew C, Meechan, Michael, Tahiri, Sophie, Rajendran, Asmitha, Berens, Michael E, Paine, Danyelle, Byron, Sara, Zhang, Jiaming, Winter, Conrad, Pakiam, Fiona, Leary, Sarah E S, Cole, Bonnie L, Jackson, Evangeline R, Dun, Matthew D, Foster, Jessica B, Evans, Myron K, Pattwell, Siobhan S, Olson, James M, Vitanza, Nicholas A

“…Constitutional mismatch repair deficiency (CMMRD) is a cancer predisposition syndrome associated with the development of hypermutant pediatric high-grade…”
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Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death by Evans, Myron K., Tovmasyan, Artak, Batinic-Haberle, Ines, Devi, Gayathri R.

“…Resistance to therapy-mediated apoptosis in inflammatory breast cancer, an aggressive and distinct subtype of breast cancer, was recently attributed to…”
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XIAP Regulation by MNK Links MAPK and NFκB Signaling to Determine an Aggressive Breast Cancer Phenotype by Evans, Myron K, Brown, Michael C, Geradts, Joseph, Bao, Xuhui, Robinson, Timothy J, Jolly, Mohit Kumar, Vermeulen, Peter B, Palmer, Gregory M, Gromeier, Matthias, Levine, Herbert, Morse, Michael A, Van Laere, Steven J, Devi, Gayathri R

“…Hyperactivation of the NFκB pathway is a distinct feature of inflammatory breast cancer (IBC), a highly proliferative and lethal disease. Gene expression…”
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Abstract 1007: Elucidating a role for the translation initiation factor, eIF4G1, in resistance to therapy in inflammatory breast cancer (IBC) by Price, Arianna, Edwards, Courtney M., Evans, Myron K., Devi, Gayathri

“…Abstract Inflammatory breast cancer (IBC) is a highly invasive and aggressive breast cancer with relatively low survival rates compared with other locally…”
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Abstract 5107: Targeting CTPS1 and nucleotide biosynthesis pathways as a novel therapeutic approach in MYC-amplified medulloblastoma by Hathaway, Matthew, Jagana, Hawa, Meechan, Michael, Hemenway, John, Gadek, Kate E., Miyaki, Aya, Terrones, Isabella, Slusher, Barbara, Pattwell, Siobhan, Vitanza, Nicholas, Evans, Myron K.

“…Abstract Although leukemia is the leading pediatric oncology diagnosis, brain tumors are the leading cause of pediatric cancer-related death. Medulloblastoma…”
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Abstract LB-015: XIAP induction by the MAPK-eIF4G1 pathway drives NFκB activation in inflammatory breast cancer growth and therapeutic resistance by Evans, Myron K., Geradts, Joseph, Edwards, Courtney, Price, Arianna, Arora, Arjun J., Aldrich, Amy J., Ramirez, Adrian, Robinson, Timothy J., Vermeulen, Peter B., van Laere, Steven, Devi, Gayathri R.

“…Abstract Inflammatory breast cancer (IBC) is the most lethal, distinct form of breast cancer, however, the basis for its aggressiveness and rapid acquisition…”
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Abstract P6-14-05: A novel link between anti-apoptotic signaling, NFκB, and SMAD7 in IBC pathobiology by Evans, Myron K, Sauer, Scott J, Aldrich, Amy J, Geradts, Joseph, Vermeulen, Peter, Dirix, Luc, Van Laere, Steven, Devi, Gayathri R

“…Abstract Background: Inflammatory breast cancer (IBC) has the highest lethality amongst all subtypes of breast cancer and develops rapid therapeutic…”
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Abstract 1667: Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity by Langdon, Casey G., Gadek, Katherine E., Garcia, Matthew R., Evans, Myron K., Reed, Kristin B., Bush, Madeline, Hanna, Jason A., Drummond, Catherine J., Maguire, Matthew C., Leavey, Patrick J., Finkelstein, David, Jin, Hongjian, Schreiner, Patrick A., Rehg, Jerold E., Hatley, Mark E.

“…Abstract Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children with no improvements in treatment options for RMS patients over the past…”
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