Search Results - "Evans, Levi"

Dietary natural products as epigenetic modifiers in aging-associated inflammation and disease by Evans, Levi W, Stratton, Matthew S, Ferguson, Bradley S

“…Covering: up to 2020Chronic, low-grade inflammation is linked to aging and has been termed "inflammaging". Inflammaging is considered a key contributor to the…”
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Food Bioactive HDAC Inhibitors in the Epigenetic Regulation of Heart Failure by Evans, Levi W, Ferguson, Bradley S

“…Approximately 5.7 million U.S. adults have been diagnosed with heart failure (HF). More concerning is that one in nine U.S. deaths included HF as a…”
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Flavan-3-ols and Cardiometabolic Health: First Ever Dietary Bioactive Guideline by Crowe-White, Kristi M, Evans, Levi W, Kuhnle, Gunter G C, Milenkovic, Dragan, Stote, Kim, Wallace, Taylor, Handu, Deepa, Senkus, Katelyn E

“…Guideline recommendation for a plant bioactive such as flavan-3-ols is a departure from previous recommendations because it is not based on deficiencies but…”
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Emodin and emodin-rich rhubarb inhibits histone deacetylase (HDAC) activity and cardiac myocyte hypertrophy by Evans, Levi W., Bender, Abigail, Burnett, Leah, Godoy, Luis, Shen, Yi, Staten, Dante, Zhou, Tong, Angermann, Jeffrey E., Ferguson, Bradley S.

“…Pathological cardiac hypertrophy is a classical hallmark of heart failure. At the molecular level, inhibition of histone deacetylase (HDAC) enzymes attenuate…”
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The Role of Histone Acetylation and the Microbiome in Phytochemical Efficacy for Cardiovascular Diseases by Evans, Levi W, Athukorala, Maheshi, Martinez-Guryn, Kristina, Ferguson, Bradley S

“…Cardiovascular diseases (CVD) are the main cause of death worldwide and create a substantial financial burden. Emerging studies have begun to focus on…”
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Integrative analysis of hepatic transcriptional profiles reveals genetic regulation of atherosclerosis in hyperlipidemic Diversity Outbred-F1 mice by Kim, Myungsuk, Huda, M. Nazmul, Evans, Levi W., Que, Excel, Gertz, Erik R., Maeda-Smithies, Nobuyo, Bennett, Brian J.

“…Atherogenesis is an insipidus but precipitating process leading to serious consequences of many cardiovascular diseases (CVD). Numerous genetic loci…”
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Specific circulating miRNAs are associated with plasma lipids in a healthy American cohort by Evans, Levi W, Durbin-Johnson, Blythe, Sutton, Kristen J, Yam, Phoebe, Bouzid, Yasmine Y, Cervantes, Eduardo, Bonnel, Ellen, Stephenson, Charles B, Bennett, Brian J

“…Low-density lipoprotein cholesterol (LDL-c) is both a therapeutic target and a risk factor for cardiovascular disease (CVD). MicroRNA (miRNA) has been shown to…”
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Use of Saliva Biomarkers to Monitor Efficacy of Vitamin C in Exercise-Induced Oxidative Stress by Evans, Levi W, Omaye, Stanley T

“…Saliva is easily obtainable for medical research and requires little effort or training for collection. Because saliva contains a variety of biological…”
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HDAC1/2‐mediated regulation of JNK and ERK phosphorylation in bovine mammary epithelial cells in response to TNF‐α by Romanick, Samantha S., Morrill, Kristen, Hostler, Andrew, Evans, Levi W., Shen, Yiqiu, Matsumura, Allison, Piotrowski, Haleigh, Silva, Lorrayny G., Faciola, Antonio P., Ferguson, Bradley S.

“…Bovine mammary epithelial cells (MAC‐Ts) are a common cell line for the study of mammary epithelial inflammation; these cells are used to mechanistically…”
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Divergent and Overlapping Roles for Selected Phytochemicals in the Regulation of Pathological Cardiac Hypertrophy by Evans, Levi, Shen, Yiqui, Bender, Abigail, Burnett, Leah E, Li, Musheng, Habibian, Justine S, Zhou, Tong, Ferguson, Bradley S

“…Plant-based foods, like fruits, vegetables, whole grains, legumes, nuts, seeds and other foodstuffs, have been deemed as heart healthy. The chemicals within…”
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Emodin Inhibited Pathological Cardiac Hypertrophy in Response to Angiotensin-Induced Hypertension and Altered the Gut Microbiome by Evans, Levi, Price, Tori, Hubert, Nathaniel, Moore, Julia, Shen, Yiqui, Athukorala, Maheshi, Frese, Steven, Martinez-Guryn, Kristina, Ferguson, Bradley S.

“…Objective: Evidence suggests that food bioactives affect the epigenome to prevent pathological cardiac hypertrophy. Recently, we showed that emodin, an…”
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PCAF regulates cardiac muscle function via non-epigenetic regulation of ACTA1 acetylation by Habibian, Justine, Evans, Levi, Ferguson, Bradley

“…Abstract only Historically, lysine acetylation has been studied in the epigenetic regulation of gene expression, in which it is known to play key roles in…”
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The HDAC Inhibitor Emodin Blocks Hypertension-Induced Cardiac Hypertrophy: A Mediating Role for the Gut? by Evans, Levi, Ferguson, Brad

“…Evidence suggests that food bioactives impact the epigenome to prevent pathological cardiac hypertrophy. Recently, we showed that emodin, an anthraquinone,…”
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Emodin Attenuates Pathological Cardiac Hypertrophy by Regulating Gene Expression Through Acetyl-histone-mediated Actions (P06-036-19) by Evans, Levi, Ferguson, Bradley

“…Epigenetic modifications regulate gene expression without changing DNA sequence and are reversible, highlighting their therapeutic potential for heart failure…”
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OR13-04-23 The Cecal Microbiome of Diversity Outbred Mice Is Regulated by Genetics, Diet, and Sex by James, Kristen, Evans, Levi, Huda, Nazmul, Gertz, Erik, Allayee, Hooman, Bennett, Brian

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PTFS02-07-23 Bioinformatics Analyses Identified an Association Between Circulating miRNA and Blood Lipids in a Healthy American Cohort by Evans, Levi, Bennett, Brian, Bonnel, Ellen, Bouzid, Yasmine, Cervantes, Eduardo, Durbin-Johnson, Blythe, James, Kristen, Stephenson, Charles, Yam, Phoebe

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The Cardioprotective Actions of Phytochemicals by Evans, Levi W

“…We found that phytochemicals similarly and differentially regulated pathways and signal transduction cascades and that these actions were associated with an…”
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Flavan-3-ols and Cardiometabolic Health: First Ever Dietary Bioactive Guideline by Crowe-White, Kristi M, Evans, Levi W, Kuhnle, Gunter G C, Milenkovic, Dragan, Stote, Kim, Wallace, Taylor, Handu, Deepa, Senkus, Katelyn E

“…Guideline recommendation for a plant bioactive such as flavan-3-ols is a departure from previous recommendations because it is not based on deficiencies but…”
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Natural product inhibitors of acetyl-lysine erasers in the prevention and treatment of heart failure by Evans, Levi W., Romanick, Samantha S., Ferguson, Bradley S.

“…Background: Heart failure (HF) is a major public health concern, with five-year mortality rates following first admission for HF being approximately 50%,…”
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Use of Saliva Biomarkers to Monitor Efficacy of Vitamin C in Exercise‐Induced Oxidative Stress by Evans, Levi W

“…Saliva is an appealing biospecimen and can be easily obtained for health research. A popular discussion in health research is oxidative stress. Systemic…”
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