Search Results - "Evans, J.F."

The discovery of rofecoxib, [MK 966, VIOXX ®, 4-(4′-methylsulfonylphenyl)-3-phenyl-2(5 H)-furanone], an orally active cyclooxygenase-2 inhibitor by Prasit, P, Wang, Z, Brideau, C, Chan, C.-C, Charleson, S, Cromlish, W, Ethier, D, Evans, J.F, Ford-Hutchinson, A.W, Gauthier, J.Y, Gordon, R, Guay, J, Gresser, M, Kargman, S, Kennedy, B, Leblanc, Y, Léger, S, Mancini, J, O'Neill, G.P, Ouellet, M, Percival, M.D, Perrier, H, Riendeau, D, Rodger, I, Tagari, P, Thérien, M, Vickers, P, Wong, E, Xu, L.-J, Young, R.N, Zamboni, R, Boyce, S, Rupniak, N, Forrest, M, Visco, D, Patrick, D

“…The development of a COX-2 inhibitor rofecoxib (MK 966, Vioxx®) is described. It is essentially equipotent to indomethacin both in vitro and in vivo but…”
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Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity by Schafer, P.H., Parton, A., Capone, L., Cedzik, D., Brady, H., Evans, J.F., Man, H.-W., Muller, G.W., Stirling, D.I., Chopra, R.

“…Apremilast, an oral small molecule inhibitor of phosphodiesterase 4 (PDE4), is in development for chronic inflammatory disorders, and has shown efficacy in…”
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Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide by Lopez-Girona, A, Mendy, D, Ito, T, Miller, K, Gandhi, A K, Kang, J, Karasawa, S, Carmel, G, Jackson, P, Abbasian, M, Mahmoudi, A, Cathers, B, Rychak, E, Gaidarova, S, Chen, R, Schafer, P H, Handa, H, Daniel, T O, Evans, J F, Chopra, R

“…Thalidomide and the immunomodulatory drug, lenalidomide, are therapeutically active in hematological malignancies. The ubiquitously expressed E3 ligase protein…”
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Shielding design of a treatment room for an accelerator-based epithermal neutron irradiation facility for BNCT by Evans, J F, Blue, T E

“…Protecting the facility personnel and the general public from radiation exposure is a primary safety concern of an accelerator-based epithermal neutron…”
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Mammalian G protein-coupled receptors for RFamide ligands by Evans, J.F.

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Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide by Lopez-Girona, A, Mendy, D, Ito, T, Miller, K, Gandhi, A.K, Kang, J, Karasawa, S, Carmel, G, Jackson, P, Abbasian, M, Mahmoudi, A, Cathers, B, Rychak, E, Gaidarova, S, Chen, R, Schafer, P.H, Handa, H, Daniel, T.O, Evans, J.F, Chopra, R

“…Thalidomide and the immunomodulatory drug, lenalidomide, are therapeutically active in hematological malignancies. The ubiquitously expressed E3 ligase protein…”
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Luminescence lifetimes of neutral nitrogen-vacancy centres in synthetic diamond containing nitrogen by Liaugaudas, G, Davies, G, Suhling, K, Khan, R U A, Evans, D J F

“…The decay time of luminescence from neutral nitrogen-vacancy (NV(0)) centres in synthetic diamond is reported. The intrinsic luminescence lifetime of NV (0) is…”
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Therapeutic Potential for Beta-3 Adrenoreceptor Agonists in Peripheral Arterial Disease and Diabetic Foot Ulcers by Evans, Cameron J F, Glastras, Sarah J, Tang, Owen, Figtree, Gemma A

“…Annually, peripheral arterial disease is estimated to cost over USD 21 billion and diabetic foot disease an estimated at USD 9-13 billion. Mirabegron is a…”
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Roaming the Changing Theoretical Landscape of Agricultural Communications by Evans, James F

“…The author comments on the role and value of dozens of theories and models he has used during more than 50 years of teaching, research, and practice in…”
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OSIRIS: A Decade of Scattered Light by McLinden, C. A., Bourassa, A. E., Brohede, S., Cooper, M., Degenstein, D. A., Evans, W. J. F., Gattinger, R. L., Haley, C. S., Llewellyn, E. J., Lloyd, N. D., Loewen, P., Martin, R. V., McConnell, J. C., McDade, I. C., Murtagh, D., Rieger, L., von Savigny, C., Sheese, P. E., Sioris, C. E., Solheim, B., Strong, K.

“…On 20 February 2001, a converted Russian ICBM delivered Odin, a small Swedish satellite, into low Earth orbit. One of the sensors onboard is a small Canadian…”
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Farmers' Voices: Concerns within the Agricultural Advertiser-Media-Reader Triad by Banning, Stephen A, Evans, James F

“…This study continues an examination of power relationships within the agricultural publishing triad: advertisers, periodicals, and producer readers. It focuses…”
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Dorsomedial hypothalamic lesions alter intake of an imbalanced amino acid diet in rats by Bellinger, L L, Evans, J F, Gietzen, D W

“…Within 3 h of ingesting an imbalanced amino acid diet (IAAD), rats show attenuated intake. The associated conditioned taste aversion can be ameliorated by…”
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Translocation of HL-60 cell 5-lipoxygenase. Inhibition of A23187- or N-formyl-methionyl-leucyl-phenylalanine-induced translocation by indole and quinoline leukotriene synthesis inhibitors by KARGMAN, S, PRASIT, P, EVANS, J. F

“…We have demonstrated translocation of HL-60 cell 5-lipoxygenase to a membrane compartment in response to both the calcium ionophore A23187 and the…”
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The vacancy as a probe of the strain in type IIa diamonds by Fisher, D., Evans, D.J.F., Glover, C., Kelly, C.J., Sheehy, M.J., Summerton, G.C.

“…The width of the vacancy related photoluminescence from diamond is used to qualitatively measure the strain in type IIa diamonds of a range of brown colours…”
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Normal development following in vitro fertilization in the cow [Embryonic development, in vivo] by Brackett, B G, Bousquet, D, Boice, M L, Donawick, W J, Evans, J F, Dressel, M A

“…A repeatable procedure for fertilization of bovine ova in vitro is described. Oocytes were recovered from ovarian follicles or from oviducts near the time of…”
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Specific absorbed fractions of energy from internal photon sources in brain tumor and cerebrospinal fluid by Evans, J F, Stabin, M G, Stubbs, J B

“…Transferrin, when injected intracranially into glioblastoma multiforme lesions, acts as a cytotoxic substance. Transferrin, radiolabeled with In-111, can be…”
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Purification and characterisation of leukotriene A4 hydrolase from rat neutrophils by Evans, J F, Dupuis, P, Ford-Hutchinson, A W

“…Leukotriene A4 hydrolase was rapidly and extensively purified from rat neutrophils using anion exchange and gel filtration high-pressure liquid chromatography…”
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Surface characterization of radio frequency water plasma treated and annealed polycrystalline tin oxide thin films by Tarlov, Michael J, Evans, John F

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Issues in equitable access to agricultural information by Evans, J.F. (University of Illinois)

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Characterization of monoclonal antibodies against human leukocyte 5-lipoxygenase by Ethier, D, Evans, J F

“…Four mouse monoclonal IgG1 antibody-producing cell lines (5LO-1, 5LO-2, 5LO-3, 5LO-4), produced against highly purified human leukocyte 5-lipoxygenase have…”
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