Search Results - "Evans, D G"

Familial Breast Cancer by Lalloo, F, Evans, D G

“…Since the localization and discovery of the first high‐risk breast cancer (BC) genes in 1990, there has been a substantial progress in unravelling its familial…”
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European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender by Seppälä, T T, Latchford, A, Negoi, I, Sampaio Soares, A, Jimenez-Rodriguez, R, Sánchez-Guillén, L, Evans, D G, Ryan, N, Crosbie, E J, Dominguez-Valentin, M, Burn, J, Kloor, M, Knebel Doeberitz, M von, Duijnhoven, F J B van, Quirke, P, Sampson, J R, Møller, P, Möslein, G

“…Lynch syndrome is the most common genetic predisposition for hereditary cancer but remains underdiagnosed. Large prospective observational studies have…”
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Systematic review of the impact of registration and screening on colorectal cancer incidence and mortality in familial adenomatous polyposis and Lynch syndrome by Barrow, P., Khan, M., Lalloo, F., Evans, D. G., Hill, J.

“…Background The British Society of Gastroenterology recommends that all familial adenomatous polyposis (FAP) and Lynch syndrome (LS) families are screened in…”
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Cumulative lifetime incidence of extracolonic cancers in Lynch syndrome: a report of 121 families with proven mutations by Barrow, E, Robinson, L, Alduaij, W, Shenton, A, Clancy, T, Lalloo, F, Hill, J, Evans, DG

“…Lynch syndrome or hereditary non‐polyposis colorectal cancer is caused by mutations of DNA mismatch repair (MMR) genes. The extracolonic tumour spectrum…”
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Distinct Immunological Landscapes Characterize Inherited and Sporadic Mismatch Repair Deficient Endometrial Cancer by Ramchander, Neal C, Ryan, Neil A J, Walker, Thomas D J, Harries, Lauren, Bolton, James, Bosse, Tjalling, Evans, D G, Crosbie, Emma J

“…Around 30% of endometrial cancers (EC) are mismatch repair (MMR) deficient, mostly as a consequence of mutations acquired during tumorigenesis, but a…”
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Risk of cancer other than breast or ovarian in individuals with BRCA1 and BRCA2 mutations by Moran, A., O’Hara, C., Khan, S., Shack, L., Woodward, E., Maher, E. R., Lalloo, F., Evans, D. G. R.

“…The risks of cancers other than breast and ovarian amongst BRCA1 and BRCA2 mutation carriers are based on relatively few family based studies with the risk of…”
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The Irminger Gyre as a Key Driver of the Subpolar North Atlantic Overturning by Sanchez‐Franks, A., Holliday, N. P., Evans, D. G., Fried, N., Tooth, O., Chafik, L., Fu, Y., Li, F., Jong, M. F., Johnson, H. L.

“…The lower limb of the Atlantic meridional overturning circulation (AMOC) is the equatorward flow of dense waters formed through the cooling and freshening of…”
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Uptake of tamoxifen in consecutive premenopausal women under surveillance in a high-risk breast cancer clinic by Donnelly, L S, Evans, D G, Wiseman, J, Fox, J, Greenhalgh, R, Affen, J, Juraskova, I, Stavrinos, P, Dawe, S, Cuzick, J, Howell, A

“…Background: Randomised trials of tamoxifen versus placebo indicate that tamoxifen reduces breast cancer risk by approximately 33%, yet uptake is low…”
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Uptake of chloride ion from aqueous solution by calcined layered double hydroxides: Equilibrium and kinetic studies by Lv, Liang, He, Jing, Wei, Min, Evans, D.G., Duan, Xue

“…Layered double hydroxides (LDH) calcined within a certain temperature range (denoted as CLDH) have been shown to recover their original layered structure in…”
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Prevalence of BRCA1 and BRCA2 mutations in triple negative breast cancer by Evans, D G, Howell, A, Ward, D, Lalloo, F, Jones, J L, Eccles, D M

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BRCA1 testing should be offered to individuals with triple-negative breast cancer diagnosed below 50 years by Robertson, L, Hanson, H, Seal, S, Warren-Perry, M, Hughes, D, Howell, I, Turnbull, C, Houlston, R, Shanley, S, Butler, S, Evans, D G, Ross, G, Eccles, D, Tutt, A, Rahman, N

“…Background: Triple-negative (TN) tumours are the predominant breast cancer subtype in BRCA1 mutation carriers. Recently, it was proposed that all individuals…”
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The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions by Antoniou, A C, Cunningham, A P, Peto, J, Evans, D G, Lalloo, F, Narod, S A, Risch, H A, Eyfjord, J E, Hopper, J L, Southey, M C, Olsson, H, Johannsson, O, Borg, A, Passini, B, Radice, P, Manoukian, S, Eccles, D M, Tang, N, Olah, E, Anton-Culver, H, Warner, E, Lubinski, J, Gronwald, J, Gorski, B, Tryggvadottir, L, Syrjakoski, K, Kallioniemi, O-P, Eerola, H, Nevanlinna, H, Pharoah, P D P, Easton, D F

“…Multiple genetic loci confer susceptibility to breast and ovarian cancers. We have previously developed a model (BOADICEA) under which susceptibility to breast…”
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Diagnostic criteria for schwannomatosis by MACCOLLIN, M, CHIOCCA, E. A, SANG, C. N, STEMMER-RACHAMIMOV, A, ROACH, E. S, EVANS, D. G, FRIEDMAN, J. M, HORVIT, R, JARAMILLO, D, LEV, M, MAUTNER, V. F, NIIMURA, M, PLOTKIN, S. R

“…The neurofibromatoses are a diverse group of genetic conditions that share a predisposition to the development of tumors of the nerve sheath. Schwannomatosis…”
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Treatment of high fluoride concentration water by MgAl-CO3 layered double hydroxides : Kinetic and equilibrium studies by LIANG LU, JING HE, MIN WEI, EVANS, D. G, ZHAOLIANG ZHOU

“…MgAl-CO(3) layered double hydroxides (LDHs) have been employed to treat high fluoride concentration solution. The influences of solution pH, initial fluoride…”
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Factors influencing the removal of fluoride from aqueous solution by calcined Mg-Al-CO3 layered double hydroxides by LIANG LV, JING HE, MIN WEI, EVANS, D. G, XUE DUAN

“…Layered double hydroxides (LDH) calcined at different temperatures (denoted as CLDH) have been demonstrated to recover their original layered structure in the…”
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Current recommendations for cancer surveillance in Gorlin syndrome: a report from the SIOPE host genome working group (SIOPE HGWG) by Guerrini-Rousseau, L., Smith, M. J., Kratz, C. P., Doergeloh, B., Hirsch, S., Hopman, S. M. J., Jorgensen, M., Kuhlen, M., Michaeli, O., Milde, T., Ridola, V., Russo, A., Salvador, H., Waespe, N., Claret, B., Brugieres, L., Evans, D. G.

“…Gorlin syndrome (MIM 109,400), a cancer predisposition syndrome related to a constitutional pathogenic variation (PV) of a gene in the Sonic Hedgehog pathway (…”
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Menopausal symptoms and bone health in women undertaking risk reducing bilateral salpingo-oophorectomy: significant bone health issues in those not taking HRT by Challberg, J, Ashcroft, L, Lalloo, F, Eckersley, B, Clayton, R, Hopwood, P, Selby, P, Howell, A, Evans, D G

“…Background: Women at high ovarian cancer risk, especially those with mutations in BRCA1/BRCA2, are encouraged to undergo bilateral risk-reducing…”
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Molecular characterisation of SMARCB1 and NF2 in familial and sporadic schwannomatosis by Hadfield, K D, Newman, W G, Bowers, N L, Wallace, A, Bolger, C, Colley, A, McCann, E, Trump, D, Prescott, T, Evans, D G R

“…Schwannomatosis is a rare condition characterised by multiple schwannomas and lack of involvement of the vestibular nerve. A recent report identified…”
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Rates of loss of heterozygosity and mitotic recombination in NF2 schwannomas, sporadic vestibular schwannomas and schwannomatosis schwannomas by Hadfield, K D, Smith, M J, Urquhart, J E, Wallace, A J, Bowers, N L, King, A T, Rutherford, S A, Trump, D, Newman, W G, Evans, D G

“…Biallelic inactivation of the NF2 gene occurs in the majority of schwannomas. This usually involves a combination of a point mutation or multiexon deletion, in…”
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Genetic testing and screening of individuals at risk of NF2 by Evans, DG, Raymond, FL, Barwell, JG, Halliday, D

“…Evans DG, Raymond FL, Barwell JG, Halliday D. Genetic testing and screening of individuals at risk of NF2. Genetic testing and management of the at‐risk…”
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