Search Results - "Evans, Conor"

Biomedical Image Processing with Containers and Deep Learning: An Automated Analysis Pipeline: Data architecture, artificial intelligence, automated processing, containerization, and clusters orchestration ease the transition from data acquisition to insights in medium-to-large datasets by González, Germán, Evans, Conor L

“…Here, a streamlined, scalable, laboratory approach is discussed that enables medium-to-large dataset analysis. The presented approach combines data management,…”
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Raman technologies in cancer diagnostics by Austin, Lauren A, Osseiran, Sam, Evans, Conor L

“…Despite significant effort, cancer still remains a leading cause of death worldwide. In order to reduce its burden, the development and improvement of…”
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Coherent anti-stokes Raman scattering microscopy: chemical imaging for biology and medicine by Evans, Conor L, Xie, X Sunney

“…Coherent anti-Stokes Raman scattering (CARS) microscopy is a label-free imaging technique that is capable of real-time, nonperturbative examination of living…”
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Oxygen-Sensing Methods in Biomedicine from the Macroscale to the Microscale by Roussakis, Emmanuel, Li, Zongxi, Nichols, Alexander J., Evans, Conor L.

“…Oxygen monitoring has been a topic of exhaustive study given its central role in the biochemistry of life. The ability to quantify the physiological…”
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Label-Free Quantification of Pharmacokinetics in Skin with Stimulated Raman Scattering Microscopy and Deep Learning by Feizpour, Amin, Marstrand, Troels, Bastholm, Louise, Eirefelt, Stefan, Evans, Conor L.

“…The treatment of inflammatory skin conditions relies on a deep understanding of how drugs and tissue behave and interact. Although numerous methods have been…”
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Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization by Celli, Jonathan P, Spring, Bryan Q, Rizvi, Imran, Evans, Conor L, Samkoe, Kimberley S, Verma, Sarika, Pogue, Brian W, Hasan, Tayyaba

“…Celli et al discuss photodynamic therapy with regard to imaging and treatment outcomes…”
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Quantifying Inflammatory Response and Drug-Aided Resolution in an Atopic Dermatitis Model with Deep Learning by Greenfield, Daniel A., Feizpour, Amin, Evans, Conor L.

“…Noninvasive quantification of dermal diseases aids efficacy studies and paves the way for broader enrollment in clinical studies across varied demographics…”
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Promotion of Proapoptotic Signals by Lysosomal Photodamage: Mechanistic Aspects and Influence of Autophagy by Kessel, David, Evans, Conor L.

“…Prior studies demonstrated that a low level (LD10–15) of lysosomal photodamage can sensitize cells to the apoptotic death that results from subsequent…”
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Nonlinear Optical Microscopy for Melanoma: Challenges, Tools and Opportunities by Evans, Conor L.

“…The natural pigments known as melanins are thought to play a role in the etiology and progression of melanoma, but many of their roles are currently not well…”
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Portable all-fiber dual-output widely tunable light source for coherent Raman imaging by Brinkmann, Maximilian, Fast, Alexander, Hellwig, Tim, Pence, Isaac, Evans, Conor L, Fallnich, Carsten

“…We present a rapidly tunable dual-output all-fiber light source for coherent Raman imaging, based on a dispersively matched mode-locked laser pumping a…”
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Sensing, monitoring, and release of therapeutics: the translational journey of next generation bandages by Li, Zongxi, Marks, Haley, Evans, Conor, Apiou-Sbirlea, Gabriela

“…This article aims to be a progress report on the Sensing, Monitoring And Release of Therapeutics (SMART) bandage-one of the three technologies that received…”
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Biomedical Image Processing with Containers and Deep Learning: An Automated Analysis Pipeline by González, Germán, Evans, Conor L.

“…Here, a streamlined, scalable, laboratory approach is discussed that enables medium‐to‐large dataset analysis. The presented approach combines data management,…”
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Recent progress in plasmonic nanoparticle‐based biomarker detection and cytometry for the study of central nervous system disorders by Peng, Fei, Jeong, Sinyoung, Ho, Alexander, Evans, Conor L.

“…Neurological disorders affect hundreds of millions of people around the world, are often life‐threatening, untreatable, and can result in debilitating…”
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Enhanced quantification of metabolic activity for individual adipocytes by label-free FLIM by Evers, Michael, Salma, Nunciada, Osseiran, Sam, Casper, Malte, Birngruber, Reginald, Evans, Conor L., Manstein, Dieter

“…Fluorescence lifetime imaging microscopy (FLIM) of intrinsic fluorophores such as nicotinamide adenine dinucleotide (NADH) allows for label-free quantification…”
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Assessment of Glial Fibrillary Acidic Protein Binding to the Surface of Leukocytes with Dark‐Field Imaging and Computational Analysis by Peng, Fei, Jeong, Sinyoung, Gonzalez, German, Marks, Haley, Ho, Alexander, Roussakis, Emmanuel, Krauledat, Petra B., Hansen, Peter, Evans, Conor L.

“…The glial fibrillary acidic protein (GFAP) is widely established as a traumatic brain injury (TBI) biomarker and can be used in early diagnosis. As essential…”
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Determining topical product bioequivalence with stimulated Raman scattering microscopy by Iliopoulos, Fotis, Tu, Dandan, Pence, Isaac J., Li, Xiaolei, Ghosh, Priyanka, Luke, Markham C., Raney, Sam G., Rantou, Elena, Evans, Conor L.

“…Generic drugs are essential for affordable medicine and improving accessibility to treatments. Bioequivalence (BE) is typically demonstrated by assessing a…”
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Killing hypoxic cell populations in a 3D tumor model with EtNBS-PDT by Evans, Conor L, Abu-Yousif, Adnan O, Park, Yong Jin, Klein, Oliver J, Celli, Jonathan P, Rizvi, Imran, Zheng, Xiang, Hasan, Tayyaba

“…An outstanding problem in cancer therapy is the battle against treatment-resistant disease. This is especially true for ovarian cancer, where the majority of…”
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Characterizing stratum corneum structure, barrier function, and chemical content of human skin with coherent Raman scattering imaging by Osseiran, Sam, Cruz, Jomer Dela, Jeong, Sinyoung, Wang, Hequn, Fthenakis, Christina, Evans, Conor L

“…The most superficial layer of the epidermis, the stratum corneum, plays a crucial role in retaining hydration; if its structure or composition is compromised,…”
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Chemical Imaging of Tissue in Vivo with Video-Rate Coherent Anti-Stokes Raman Scattering Microscopy by Conor L. Evans, Potma, Eric O., Mehron Puoris'haag, Daniel Côté, Lin, Charles P., Xie, X. Sunney

“…Imaging living organisms with molecular selectivity typically requires the introduction of specific labels. Many applications in biology and medicine, however,…”
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Bright, "Clickable" Porphyrins for the Visualization of Oxygenation under Ambient Light by Roussakis, Emmanuel, Li, Zongxi, Nowell, Nicholas H., Nichols, Alexander J., Evans, Conor L.

“…A new group of “clickable” and brightly emissive metalloporphyrins has been developed for the visualization of oxygenation under ambient light with the naked…”
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