Search Results - "Eva Pazourkova"
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Performance of Droplet Digital PCR in Non-Invasive Fetal RHD Genotyping - Comparison with a Routine Real-Time PCR Based Approach
Published in PloS one (12-11-2015)“…Detection and characterization of circulating cell-free fetal DNA (cffDNA) from maternal circulation requires an extremely sensitive and precise method due to…”
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2
Analysis of microRNAs in Small Urinary Extracellular Vesicles and Their Potential Roles in Pathogenesis of Renal ANCA-Associated Vasculitis
Published in International journal of molecular sciences (14-04-2022)“…Antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) represents an autoimmunity disease characterized by high mortality. For successful…”
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Impacts of an extreme flood on the ecosystem of a headwater stream
Published in Journal of limnology (01-01-2021)“…Headwater streams are the smallest parts of rivers but make up the majority of river miles. The chemistry and macroinvertebrate composition of such streams are…”
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The impact of standard chemotherapy on miRNA signature in plasma in AML patients
Published in Leukemia research (01-12-2015)“…Highlights • We examined paired plasma samples in AML patients at diagnosis and in remission. • All patients received standard chemotherapy and were examined…”
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Role of forests in headwater control with changing environment and society
Published in International Soil and Water Conservation Research (01-03-2021)“…Forest practices in headwater catchments are related to environmental and social contexts. The aim of this study is to analyse the changing protective…”
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Soil conservation in a forested mountain catchment
Published in EQA (Imola. 2009) (01-01-2019)“…In 1982 – 2015, environmental impacts of commercial forestry practices were studied in the Jizerka experimental catchment (the Jizera Mountains, Czech…”
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Differentially expressed miRNAs in trisomy 21 placentas
Published in Prenatal diagnosis (01-08-2016)“…Objective Molecular pathogenesis of Down syndrome (DS) is still incompletely understood. Epigenetic mechanisms, including miRNAs gene expression regulation,…”
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Serum microRNA-196 and microRNA-200 in pancreatic ductal adenocarcinoma of patients with diabetes mellitus
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-09-2016)“…Abstract Background/Objectives Our aim was to compare expressions of 6 microRNAs (miRNAs) in patients with pancreatic ductal adenocarcinoma (PAC) and…”
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Quantification of circulating fetal DNA as a tool for potential monitoring of pregnant patients with antiphospholipid antibodies
Published in Autoimmunity (Chur, Switzerland) (01-11-2014)“…Abstract Apoptosis of tissues of fetal origin is thought to be one of the main sources of cell-free fetal DNA (cffDNA) in maternal circulation, impaired…”
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Rapid non-invasive prenatal screening test for trisomy 21 based on digital droplet PCR
Published in Scientific reports (22-12-2023)“…Non-invasive prenatal tests for the detection of fetal aneuploidies are predominantly based on the analysis of cell-free DNA (cfDNA) from the plasma of…”
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Genome-wide miRNA profiling in plasma of pregnant women with down syndrome fetuses
Published in Molecular biology reports (01-06-2020)“…Down syndrome (DS) is one of the most common causes of intellectual disability and new approaches allowing its rapid and effective prenatal detection are being…”
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Detection of cell-free foetal DNA fraction in female-foetus bearing pregnancies using X-chromosomal insertion/deletion polymorphisms examined by digital droplet PCR
Published in Scientific reports (18-11-2020)“…In families with X-linked recessive diseases, foetal sex is determined prenatally by detection of Y-chromosomal sequences in cell-free foetal DNA (cffDNA) in…”
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13
Accessing Insurance Flood Losses Using a Catastrophe Model and Climate Change Scenarios
Published in Climate (Basel) (01-05-2022)“…Impact Forecasting has developed a catastrophe flood model for Czechia to estimate insurance losses. The model is built on a dataset of 12,066 years of daily…”
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Optimization of diagnostic strategy for non‐invasive cell‐free foetal RHD determination from maternal plasma
Published in Vox sanguinis (01-10-2021)“…Background and objectives The aim of the study was to optimize routine non‐invasive prenatal detection of fetal RHD gene from plasma of RhD‐negative pregnant…”
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Mutational landscape of plasma cell-free DNA identifies molecular features associated with therapeutic response in patients with colon cancer. A pilot study
Published in Mutagenesis (06-10-2021)“…Abstract Cell-free DNA (cfDNA) has recently been used as a non-invasive diagnostic tool for detecting tumour-specific mutations. cfDNA may also be used for…”
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Cell-free nucleic acids as biomarkers in dialyzed patients
Published in Journal of nephrology (01-11-2013)“…In this review, we discuss the origin, possible biological meaning, quantitative and qualitative changes in the concentrations of cell-free nucleic acids in…”
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Urinary Cell-Free DNA Quantification as Non-Invasive Biomarker in Patients with Bladder Cancer
Published in Urologia internationalis (01-01-2016)“…Concentration of urinary cell-free DNA (ucfDNA) belongs to potential bladder cancer markers, but the reported results are inconsistent due to the use of…”
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Comparison of MicroRNA Content in Plasma and Urine Indicates the Existence of a Transrenal Passage of Selected MicroRNAs
Published in Advances in experimental medicine and biology (2016)“…MicroRNAs (miRNAs) in urine are examined as potential biomarkers. We examined the urine samples from 70 individuals (45 males, 25 females, mean age 65 years,…”
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Alterations in methylation status of immune response genes promoters in cell-free DNA during a hemodialysis procedure
Published in Expert opinion on biological therapy (01-06-2012)“…Elevations of cell-free DNA (cfDNA) concentrations during hemodialysis (HD) sessions were reported in numerous studies regardless of an applied therapeutic…”
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Methylation status of immune response genes promoters in cell-free DNA differs in hemodialyzed patients with diabetic nephropathy according to the intensity of anemia therapy
Published in Blood purification (01-01-2013)“…Anemia is a major complication of end-stage renal disease. Hemodialysis itself is regarded as a stimulus activating inflammation. Pro-inflammatory cytokines…”
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