Search Results - "Eva, Michalová"
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Ferroptosis as a New Type of Cell Death and its Role in Cancer Treatment
Published in Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti (2018)“…Ferroptosis is a recently discovered type of cell death. It is genetically, morphologically, and biochemically distinct from other types of programmed cell…”
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Acetylsalicylic Acid and its Potential for Chemoprevention of Colorectal Carcinoma
Published in Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti (2018)“…Non-steroidal anti-inflammatory drugs (NSAID) represent a group of medicaments inhibiting cyclooxygenase (COX) enzyme, and, in parallel, these drugs show also…”
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The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells
Published in RNA biology (01-05-2012)“…The untranslated regions (UTRs) at the 3'end of mRNA transcripts contain important sequences that influence the fate of mRNA and thus proteosynthesis. In this…”
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AGR2 oncoprotein inhibits p38 MAPK and p53 activation through a DUSP10-mediated regulatory pathway
Published in Molecular oncology (01-05-2016)“…The tumor suppressor p53 plays a key role in malignant transformation and tumor development. However, the frequency of p53 mutations within individual types of…”
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Impaired pre-mRNA processing and altered architecture of 3' untranslated regions contribute to the development of human disorders
Published in International Journal of Molecular Sciences (26-07-2013)“…The biological fate of each mRNA and consequently, the protein to be synthesised, is highly dependent on the nature of the 3' untranslated region. Despite its…”
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New Approaches for Chemosensitivity Testing in Malignant Diseases
Published in Klinická onkologie (2018)“…Due to the irreplaceable role of chemotherapy in cancer treatment, research has focused on improving the efficacies of individual drugs and minimizing, or…”
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The effect of cellular environment and p53 status on the mode of action of the platinum derivative LA-12
Published in Investigational new drugs (01-08-2010)“…Summary In this study, we characterized the effects of LA-12 on tumor cell lines possessing wild type p53 and on p53-deficient/mutant cell lines and the…”
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Methods for studying tumor cell migration and invasiveness
Published in Klinická onkologie (15-06-2014)“…Migration and invasiveness are phenotypic characteristics of cells that contribute to physiological processes, such as wound healing or embryogenesis and they…”
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Quantitative mass spectrometry and its utilization in oncology
Published in Klinická onkologie (15-06-2014)“…Cancers are genetically and clinically very heterogeneous diseases; therefore, various proteomic studies have been trying to find bio-markers which can…”
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Development of PCR methods and their applications in oncological research and practice
Published in Klinická onkologie (15-06-2014)“…Since its discovery, PCR has become a conventional method of molecular biology research laboratories and an indispensable tool in diagnostic medicine. Multiple…”
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Tetracyclines in veterinary medicine and bacterial resistance to them
Published in Veterinární medicína (01-03-2004)“…Since their discovery in 1945, tetracyclines have been used extensively in the therapy and prophylaxis of infectious diseases and as growth promoters. These…”
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