Search Results - "European journal of clinical pharmacology"

Therapeutic drug monitoring of oral targeted antineoplastic drugs by Mueller-Schoell, Anna, Groenland, Stefanie L., Scherf-Clavel, Oliver, van Dyk, Madelé, Huisinga, Wilhelm, Michelet, Robin, Jaehde, Ulrich, Steeghs, Neeltje, Huitema, Alwin D.R., Kloft, Charlotte

“…Purpose This review provides an overview of the current challenges in oral targeted antineoplastic drug (OAD) dosing and outlines the unexploited value of…”
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Potentially inappropriate medication in the elderly: a systematic review of validated explicit criteria by Motter, Fabiane Raquel, Fritzen, Janaína Soder, Hilmer, Sarah Nicole, Paniz, Érika Vieira, Paniz, Vera Maria Vieira

“…Purpose Potentially inappropriate medication (PIM) use causes preventable adverse drug reactions in older patients. Several assessment tools have been…”
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Hospital admissions due to adverse drug reactions in the elderly. A meta-analysis by Oscanoa, T. J., Lizaraso, F., Carvajal, Alfonso

“…Introduction It is currently admitted that adverse drug reactions (ADRs) account for a great burden of disease. Of particular concern are ADR-induced hospital…”
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The EU(7)-PIM list: a list of potentially inappropriate medications for older people consented by experts from seven European countries by Renom-Guiteras, Anna, Meyer, Gabriele, Thürmann, Petra A.

“…Purpose The aim of the study was to develop a European list of potentially inappropriate medications (PIM) for older people, which can be used for the analysis…”
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Inhibition of SARS-CoV-2 entry through the ACE2/TMPRSS2 pathway: a promising approach for uncovering early COVID-19 drug therapies by Ragia, Georgia, Manolopoulos, Vangelis G.

“…Aim The COVID-19 pandemic caused by infection with the novel coronavirus SARS-CoV-2 is urging the scientific community worldwide to intense efforts for…”
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Proton pump inhibitor use: systematic review of global trends and practices by Shanika, Lelwala Guruge Thushani, Reynolds, Andrew, Pattison, Sharon, Braund, Rhiannon

“…Purpose Proton pump inhibitors (PPIs) reduce acid secretion in the stomach and rank as one of the most widely used acid-suppressing medicines globally. While…”
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Potentially inappropriate prescribing in community-dwelling older people across Europe: a systematic literature review by Tommelein, Eline, Mehuys, Els, Petrovic, Mirko, Somers, Annemie, Colin, Pieter, Boussery, Koen

“…Background Potentially inappropriate prescribing (PIP) is one of the main risk factors for adverse drug events (ADEs) in older people. Purpose This systematic…”
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Clinical pharmacokinetics of melatonin: a systematic review by Harpsøe, Nathja Groth, Andersen, Lars Peter Holst, Gögenur, Ismail, Rosenberg, Jacob

“…Purpose The aim of the review was to provide an overview of studies investigating the pharmacokinetics of exogenous melatonin in humans and if possible, to…”
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What about COVID-19 and arachidonic acid pathway? by Hoxha, Malvina

“…Background and objective COVID-19 is a highly contagious viral disease. In this study, we tried to define and discuss all the findings on the potential…”
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A review on colistin nephrotoxicity by Ordooei Javan, Atefeh, Shokouhi, Shervin, Sahraei, Zahra

“…Purpose Colistin is an antibiotic that was introduced many years ago and was withdrawn because of its nephrotoxicity. Nowadays, reemergence of this antibiotic…”
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Use of proton pump inhibitors in adults in France: a nationwide drug utilization study by Lassalle, Marion, Le Tri, Thien, Bardou, Marc, Biour, Michel, Kirchgesner, Julien, Rouby, Frank, Dumarcet, Nathalie, Zureik, Mahmoud, Dray-Spira, Rosemary

“…Purpose Proton pump inhibitor (PPI) drugs are approved for the management of gastric acid–related diseases, mainly treatment of gastroesophageal reflux…”
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A systematic review of interventions to deprescribe benzodiazepines and other hypnotics among older people by Reeve, Emily, Ong, Magdalene, Wu, Angela, Jansen, Jesse, Petrovic, Mirko, Gnjidic, Danijela

“…Purpose Benzodiazepines are effective medicines for insomnia and anxiety but are commonly used beyond recommended treatment time frames, which may lead to…”
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Quality of anticholinergic burden scales and their impact on clinical outcomes: a systematic review by Lisibach, Angela, Benelli, Valérie, Ceppi, Marco Giacomo, Waldner-Knogler, Karin, Csajka, Chantal, Lutters, Monika

“…Purpose Older people are at risk of anticholinergic side effects due to changes affecting drug elimination and higher sensitivity to drug’s side effects…”
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Safety, pharmacokinetic and pharmacodynamic properties of single ascending dose and continuous infusion of remimazolam besylate in healthy Chinese volunteers by Sheng, Xiao-yan, Liang, Yan, Yang, Xue-yuan, Li, Li-e, Ye, Xia, Zhao, Xia, Cui, Yi-min

“…Purpose The aim of the present study was to evaluate the safety, pharmacokinetic (PK) and pharmacodynamic (PD) properties of remimazolam besylate following…”
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Antibacterial antibiotic-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a literature review by Sharifzadeh, Shiva, Mohammadpour, Amir Hooshang, Tavanaee, Ashraf, Elyasi, Sepideh

“…Background Drug reaction with eosinophilia and systemic symptoms syndrome (DRESS) is a delayed infrequent potentially life-threatening idiosyncratic drug…”
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The added value of pirfenidone to fight inflammation and fibrotic state induced by SARS-CoV-2: Anti-inflammatory and anti-fibrotic therapy could solve the lung complications of the infection? by Ferrara, Francesco, Granata, Giovanni, Pelliccia, Chiara, La Porta, Raffaele, Vitiello, Antonio

“…Aim SARS-CoV-2 infection has been divided by scientific opinion into three phases: the first as asymptomatic or slightly symptomatic and the second and the…”
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Global prevalence and types of complementary and alternative medicines use amongst adults with diabetes: systematic review and meta-analysis by Alzahrani, Abdulaziz S., Price, Malcolm J., Greenfield, Sheila M., Paudyal, Vibhu

“…Aim This study aimed to undertake a systematic review and meta-analysis of global prevalence and types of complementary and alternative medicine (CAM) use…”
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Systematic review of anticholinergic risk scales in older adults by Durán, Carlos E., Azermai, Majda, Vander Stichele, Robert H.

“…Background Anticholinergic drugs are often involved in explicit criteria for inappropriate prescribing in older adults. Several scales were developed for…”
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The nocebo effect challenges the non-medical infliximab switch in practice by Boone, N. W., Liu, L., Romberg-Camps, M. J., Duijsens, L., Houwen, C., van der Kuy, P. H. M., Janknegt, R., Peeters, R., Landewé, R. B. M., Winkens, B., van Bodegraven, A. A.

“…Background In clinical practice, non-medical switching of biological medication may provoke nocebo effects due to unexplained deterioration of therapeutic…”
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Drug-drug interactions and their harmful effects in hospitalised patients: a systematic review and meta-analysis by Zheng, Wu Yi, Richardson, L. C., Li, L., Day, R. O., Westbrook, J. I., Baysari, M. T.

“…Purpose Drug-drug interactions (DDIs) are often avoidable and, if undetected, can lead to patient harm. This review aimed to determine the prevalence of…”
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