Search Results - "Europe, Cosmetics"

Expansion of the Cosmetics Europe skin sensitisation database with new substances and PPRA data by Hoffmann, Sebastian, Alépée, Nathalie, Gilmour, Nicola, Kern, Petra S., van Vliet, Erwin, Boislève, Fanny, Bury, Dagmar, Cloudet, Elodie, Klaric, Martina, Kühnl, Jochen, Lalko, Jon F., Mewes, Karsten, Miyazawa, Masaaki, Nishida, Hayato, Tam Brami, Mai Thanh, Varçin, Mustafa, Api, Anne Marie, Europe, Cosmetics

“…The assessment of skin sensitisation is a key requirement in all regulated sectors, with the European Union's regulation of cosmetic ingredients being most…”
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A 10-step framework for use of read-across (RAX) in next generation risk assessment (NGRA) for cosmetics safety assessment by Alexander-White, Camilla, Bury, Dagmar, Cronin, Mark, Dent, Matthew, Hack, Eric, Hewitt, Nicola J., Kenna, Gerry, Naciff, Jorge, Ouedraogo, Gladys, Schepky, Andreas, Mahony, Catherine, Europe, Cosmetics

“…This paper presents a 10-step read-across (RAX) framework for use in cases where a threshold of toxicological concern (TTC) approach to cosmetics safety…”
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Applying a Next Generation Risk Assessment Framework for Skin Sensitization to Inconsistent New Approach Methodology Information by Gilmour, Nicola, Alepee, Nathalie, Hoffmann, Sebastian, Kern, Petra S, van Vliet, Erwin, Bury, Dagmar, Miyazawa, Masaaki, Nishida, Hayato

“…Cosmetic products must be safe for their intended use. Regulatory bans on animal testing for new ingredients have resulted in a shift towards the use of new…”
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Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment – A case study with parabens by Ouedraogo, Gladys, Alexander-White, Camilla, Bury, Dagmar, Clewell, Harvey J., Cronin, Mark, Cull, Tom, Dent, Matthew, Desprez, Bertrand, Detroyer, Ann, Ellison, Corie, Giammanco, Stefania, Hack, Eric, Hewitt, Nicola J., Kenna, Gerry, Klaric, Martina, Kreiling, Reinhard, Lester, Cathy, Mahony, Catherine, Mombelli, Enrico, Naciff, Jorge, O'Brien, John, Schepky, Andreas, Tozer, Sarah, van der Burg, Bart, van Vugt-Lussenburg, Barbara, Stuard, Sharon, Cosmetics Europe

“…Parabens are esters of para-hydroxybenzoic acid that have been used as preservatives in many types of products for decades including agrochemicals,…”
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Use of in vitro metabolism and biokinetics assays to refine predicted in vivo and in vitro internal exposure to the cosmetic ingredient, phenoxyethanol, for use in risk assessment by Hewitt, Nicola J., Troutman, John, Przibilla, Julia, Schepky, Andreas, Ouédraogo, Gladys, Mahony, Catherine, Kenna, Gerry, Varçin, Mustafa, Dent, Mathew P.

“…A novel approach was developed to help characterize the biokinetics of the cosmetic ingredient, phenoxyethanol, to help assess the safety of the parent and its…”
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Applying a next generation risk assessment framework for skin sensitisation to inconsistent new approach methodology information by Gilmour, Nicola, Alépée, Nathalie, Hoffmann, Sebastian, Kern, Petra S, Van Vliet, Erwin, Bury, Dagmar, Miyazawa, Masaaki, Nishida, Hayato, Cosmetics Europe

“…Cosmetic products must be safe for their intended use. Regulatory bans on animal testing for new ingredients have resulted in a shift towards the use of new…”
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