Search Results - "Eun Sook Jeong"

Novel oral transforming growth factor‐β signaling inhibitor EW‐7197 eradicates CML‐initiating cells by Naka, Kazuhito, Ishihara, Kaori, Jomen, Yoshie, Jin, Cheng Hua, Kim, Dong‐Hyun, Gu, Yoon‐Kang, Jeong, Eun‐Sook, Li, Shaoguang, Krause, Daniela S., Kim, Dong‐Wook, Bae, Eunjin, Takihara, Yoshihiro, Hirao, Atsushi, Oshima, Hiroko, Oshima, Masanobu, Ooshima, Akira, Sheen, Yhun Yhong, Kim, Seong‐Jin, Kim, Dae‐Kee

“…Recent strategies for treating CML patients have focused on investigating new combinations of tyrosine kinase inhibitors (TKIs) as well as identifying novel…”
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Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model by Jeong, Eun-Sook, Bajgai, Johny, You, In-Soo, Rahman, Md Habibur, Fadriquela, Ailyn, Sharma, Subham, Kwon, Hwang-Un, Lee, So-Yeon, Kim, Cheol-Su, Lee, Kyu-Jae

“…Oxidative stress (OS) is one of the causative factors in the pathogenesis of various neurodegenerative diseases, including Alzheimer's disease (AD) and…”
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Redox-Mechanisms of Molecular Hydrogen Promote Healthful Longevity by Rahman, Md Habibur, Jeong, Eun-Sook, You, Hae Sun, Kim, Cheol-Su, Lee, Kyu-Jae

“…Age-related diseases represent the largest threat to public health. Aging is a degenerative, systemic, multifactorial and progressive process, coupled with…”
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Effects of Hydrogen Gas Inhalation on Community-Dwelling Adults of Various Ages: A Single-Arm, Open-Label, Prospective Clinical Trial by Rahman, Md Habibur, Bajgai, Johny, Sharma, Subham, Jeong, Eun-Sook, Goh, Seong Hoon, Jang, Yeon-Gyu, Kim, Cheol-Su, Lee, Kyu-Jae

“…Molecular hydrogen (H ) is a versatile therapeutic agent. H gas inhalation is reportedly safe and has a positive impact on a range of illnesses, including…”
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Glucuronidation of fimasartan, a new angiotensin receptor antagonist, is mainly mediated by UGT1A3 by Jeong, Eun-Sook, Kim, Yang-Weon, Kim, Hyo-Ji, Shin, Ho-Jung, Shin, Jae-Gook, Kim, Kwang Hee, Chi, Yong Ha, Paik, Soo Heui, Kim, Dong-Hyun

“…Abstract 1. Fimasartan is an angiotensin receptor II antagonist used to treat patients with hypertension. This drug is mainly excreted into bile as either the…”
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Simple and accurate quantitative analysis of 20 anti-tuberculosis drugs in human plasma using liquid chromatography–electrospray ionization–tandem mass spectrometry by Kim, Hyo-Ji, Seo, Kyung-Ah, Kim, Hyun-Mi, Jeong, Eun-Sook, Ghim, Jong Lyul, Lee, Seung Heon, Lee, Young Min, Kim, Dong Hyun, Shin, Jae-Gook

“…•Simultaneous analysis of 20 anti-tuberculosis drugs in human plasma.•Fast and simple sample treatments were applied.•LC–MS/MS analyses were performed in less…”
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Simultaneous Determination of Synthetic Phosphodiesterase-5 Inhibitors in Dietary Supplements by Liquid Chromatography-High Resolution/Mass Spectrometry by So-hee Kim, Ho Jun Kim, Junghyun Son, Byoung Wook Jeon, Eun Sook Jeong, Eun Ju Cha, Jaeick Lee

“…After success of sildenafil for the treatment of erectile dysfunction, a large number of its analogues have beenapproved from FDA. Recently, the illegal…”
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Microbial Activation of Bacillus subtilis-Immobilized Microgel Particles for Enhanced Oil Recovery by Son, Han Am, Choi, Sang Koo, Jeong, Eun Sook, Kim, Bohyun, Kim, Hyun Tae, Sung, Won Mo, Kim, Jin Woong

“…Microbially enhanced oil recovery involves the use of microorganisms to extract oil remaining in reservoirs. Here, we report fabrication of microgel particles…”
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In vitro assay of six UDP-glucuronosyltransferase isoforms in human liver microsomes, using cocktails of probe substrates and liquid chromatography-tandem mass spectrometry by Seo, Kyung-Ah, Kim, Hyo-Ji, Jeong, Eun Sook, Abdalla, Nagi, Choi, Chang-Soo, Kim, Dong-Hyun, Shin, Jae-Gook

“…UDP-glucuronosyltransferase (UGT)-mediated drug-drug interactions are commonly evaluated during drug development. We present a validated method for the…”
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Cytotoxic germacranolide sesquiterpene lactones from Carpesium triste var. manshuricum by Kim, Mi-Ran, Hwang, Bang Yeon, Jeong, Eun-Sook, Lee, Yong-Moon, Yoo, Hwan-Soo, Chung, Youn-Bok, Hong, Jin Tae, Moon, Dong-Cheul

“…Four known germacranolide sesquiterpene lactones, 2alpha,5-epoxy-5,10-dihydroxy-6alpha-angeloyloxy-9beta-isobutyloxy-germacran-8alpha,12-olide (1),…”
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Increased serum bile acid concentration following low-dose chronic administration of thioacetamide in rats, as evidenced by metabolomic analysis by Jeong, Eun Sook, Kim, Gabin, Shin, Ho Jung, Park, Se-Myo, Oh, Jung-Hwa, Kim, Yong-Bum, Moon, Kyoung-Sik, Choi, Hyung-Kyoon, Jeong, Jayoung, Shin, Jae-Gook, Kim, Dong Hyun

“…A liquid chromatography/time-of-flight mass spectrometry (LC/TOF-MS)-based metabolomics approach was employed to identify endogenous metabolites as potential…”
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Validation and Applications of Gas Chromatography-Combustion/isotope Ratio Mass Spectrometric Method to Control Misuse of Androgens in Human by Kang Mi Lee, Ho Jun Kim, Eun Sook Jeong, Hye Hyun Yoo, Oh Seung Kwon, Changbae Jin, Dong Hyun Kim, Jaeick Lee

“…The misuse of anabolic androgenic steroids is of particular concern in sports and society. Thus, it is of great importance todiscriminate endogenous steroids…”
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Determination of eperisone in human plasma by liquid chromatography-ESI-tandem mass spectrometry by Jeoung, Min Kyo, Jeong, Eun Sook, Kim, Nam Hee, Kim, Chang-Soo, Chung, Youn-Bok, Lee, Yong-Moon, Ahn, Su-Youn, Cho, Hwang-Eui, Lee, Yong Hwa, Hong, Jin Tae, Moon, Dong-Cheul

“…A sensitive and selective method for the determination of 4'-ethyl-3-methyl-3-piperidinopropiophenone hydrochloride (eperisone hydrochloride) in human plasma…”
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Multiple cytochrome P450 isoforms are involved in the generation of a pharmacologically active thiol metabolite, whereas paraoxonase 1 and carboxylesterase 1 catalyze the formation of a thiol metabolite isomer from ticlopidine by Kim, Min-Jung, Jeong, Eun Sook, Park, Jung-Soon, Lee, Su-Jun, Ghim, Jong Lyul, Choi, Chang-Soo, Shin, Jae-Gook, Kim, Dong-Hyun

“…Ticlopidine is a first-generation thienopyridine antiplatelet drug that prevents adenosine 5'-diphosphate (ADP)-induced platelet aggregation. We identified the…”
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LC-ESI/MS/MS method for rapid screening and confirmation of 44 exogenous anabolic steroids in human urine by Jeon, Byoung Wook, Yoo, Hye Hyun, Jeong, Eun Sook, Kim, Ho Jun, Jin, Changbae, Kim, Dong Hyun, Lee, Jaeick

“…A sensitive and rapid method based on liquid chromatography–triple-quadrupole tandem mass spectrometry (LC-MS/MS) with electrospray ionization (ESI) has been…”
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Ultra-fast Generic LC-MS/MS Method for High-Throughput Quantification in Drug Discovery by Kim, So-Hee, Yoo, Hye Hyun, Cha, Eun-Ju, Jeong, Eun Sook, Kim, Ho Jun, Kim, Dong Hyun, Lee, Jaeick

“…An ultra-fast generic LC-MS/MS method was developed for high-throughput quantification of discovery pharmacokinetic (PK) samples and its reliability was…”
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Glucuronidation of a sarpogrelate active metabolite is mediated by UDP-glucuronosyltransferases 1A4, 1A9, and 2B4 by Kim, Hyo-Ji, Jeong, Eun Sook, Seo, Kyung-Ah, Shin, Kye Jung, Choi, Yeon Jae, Lee, Su-Jun, Ghim, Jong Lyul, Sohn, Dong-Ryul, Shin, Jae-Gook, Kim, Dong-Hyun

“…Sarpogrelate is a selective serotonin 5-HT2A-receptor antagonist used to treat patients with peripheral arterial disease. This drug is rapidly hydrolyzed to…”
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Simultaneous Determination of Synthetic Phosphodiesterase-5 Inhibitors in Dietary Supplements by Liquid Chromatography-High Resolution/Mass Spectrometry by Kim, So-Hee, Kim, Ho-Jun, Son, Jung-Hyun, Jeon, Byoung-Wook, Jeong, Eun-Sook, Cha, Eun-Ju, Lee, Jae-Ick

“…After success of sildenafil for the treatment of erectile dysfunction, a large number of its analogues have been approved from FDA. Recently, the illegal…”
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Enantioselective N-Demethylation and Hydroxylation of Sibutramine in Human Liver Microsomes and Recombinant Cytochrome P-450 Isoforms by Shinde, Dhananjay D., Kim, Min-Jung, Jeong, Eun-Sook, Kim, Yang-Weon, Lee, Ji-Woo, Shin, Jae-Gook, Kim, Dong-Hyun

“…The enantioselective metabolism of sibutramine was examined using human liver microsomes (HLM) and recombinant cytochrome P-450 (CYP) isoforms. This drug is…”
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Separation and determination of polyethylene glycol fatty acid esters in cosmetics by a reversed-phase HPLC/ELSD by Lee, Yong Hwa, Jeong, Eun Sook, Cho, Hwang Eui, Moon, Dong-Cheul

“…A comprehensive analytical method was established for the separation of polyethylene glycol (PEG) stearates according to the distribution of ethylene oxide…”
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