Search Results - "Eum, Seok‐Yong"
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Transient drug-tolerance and permanent drug-resistance rely on the trehalose-catalytic shift in Mycobacterium tuberculosis
Published in Nature communications (02-07-2019)“…Stochastic formation of Mycobacterium tuberculosis (Mtb) persisters achieves a high level of antibiotic-tolerance and serves as a source of multidrug-resistant…”
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2
Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB
Published in Chest (01-01-2010)“…The exact role of neutrophils in the pathogenesis of TB is poorly understood. Recent evidence suggests that neutrophils are not simply scavenging phagocytes in…”
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3
Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates
Published in Infection and Immunity (01-06-2008)“…Understanding the physical characteristics of the local microenvironment in which Mycobacterium tuberculosis resides is an important goal that may allow the…”
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4
Effect of teriparatide on drug treatment of tuberculous spondylitis: an experimental study
Published in Scientific reports (15-12-2022)“…Tuberculous spondylitis often develops catastrophic bone destruction with uncontrolled inflammation. Because anti-tuberculous drugs do not have a role in bone…”
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5
Comparison of immunogenicity and vaccine efficacy between heat-shock proteins, HSP70 and GrpE, in the DnaK operon of Mycobacterium tuberculosis
Published in Scientific reports (26-09-2018)“…Antigens (Ags) in Mycobacterium tuberculosis (Mtb) that are constitutively expressed, overexpressed during growth, essential for survival, and highly conserved…”
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6
Virulence-Dependent Alterations in the Kinetics of Immune Cells during Pulmonary Infection by Mycobacterium tuberculosis
Published in PloS one (16-12-2015)“…A better understanding of the kinetics of accumulated immune cells that are involved in pathophysiology during Mycobacterium tuberculosis (Mtb) infection may…”
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7
Efficacy and Safety of Metronidazole for Pulmonary Multidrug-Resistant Tuberculosis
Published in Antimicrobial Agents and Chemotherapy (01-08-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A Rapid Assessing Method of Drug Susceptibility Using Flow Cytometry for Mycobacterium tuberculosis Isolates Resistant to Isoniazid, Rifampin, and Ethambutol
Published in Tuberculosis and respiratory diseases (01-07-2022)“…Background: The current conventional drug susceptibility test (DST) for Mycobacterium tuberculosis (Mtb) takes several weeks of incubation to obtain results…”
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9
Repeated Aerosolized-Boosting with Gamma-Irradiated Mycobacterium bovis BCG Confers Improved Pulmonary Protection against the Hypervirulent Mycobacterium tuberculosis Strain HN878 in Mice
Published in PloS one (28-10-2015)“…Mycobacterium bovis bacillus Calmette-Guerin (BCG), the only licensed vaccine, shows limited protection efficacy against pulmonary tuberculosis (TB),…”
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10
Mycolic acids as diagnostic markers for tuberculosis case detection in humans and drug efficacy in mice
Published in EMBO molecular medicine (01-01-2012)“…Mycolic acids are attractive diagnostic markers for tuberculosis (TB) infection because they are bacteria‐derived, contain information about bacterial species,…”
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11
Genetic Diversity of Mycobacterium tuberculosis Isolates from a Tertiary Care Tuberculosis Hospital in South Korea
Published in Journal of Clinical Microbiology (01-02-2010)“…Tuberculosis (TB) remains an immense public health problem in the Republic of Korea despite a more than fivefold decrease in the prevalence of the disease over…”
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12
Plant-Produced N-glycosylated Ag85A Exhibits Enhanced Vaccine Efficacy Against Mycobacterium tuberculosis HN878 Through Balanced Multifunctional Th1 T Cell Immunity
Published in Vaccines (Basel) (18-04-2020)“…Tuberculosis (TB) is one of the deadliest infectious diseases worldwide and is caused by (Mtb). An effective vaccine to prevent TB is considered the most…”
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13
IL-13 may mediate allergen-induced hyperresponsiveness independently of IL-5 or eotaxin by effects on airway smooth muscle
Published in American journal of physiology. Lung cellular and molecular physiology (01-03-2005)“…IL-13 is a mediator of allergen-induced airway hyperresponsiveness (AHR). The aim of this study was to evaluate whether eotaxin and IL-5 were implicated in the…”
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14
Differential immune responses to Segniliparus rotundus and Segniliparus rugosus infection and analysis of their comparative virulence profiles
Published in PloS one (29-03-2013)“…Two closely related bacterial species, Segniliparus rotundus and Segniliparus rugosus, have emerged as important human pathogens, but little is known about the…”
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15
Phosphoenolpyruvate depletion mediates both growth arrest and drug tolerance of Mycobacterium tuberculosis in hypoxia
Published in Proceedings of the National Academy of Sciences - PNAS (31-08-2021)“…Mycobacterium tuberculosis (Mtb) infection is difficult to treat because Mtb spends the majority of its life cycle in a nonreplicating (NR) state. Since NR Mtb…”
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16
Kinetics of IFN-gamma and TNF-alpha gene expression and their relationship with disease progression after infection with Mycobacterium tuberculosis in guinea pigs
Published in Yonsei medical journal (01-05-2013)“…Guinea pig is one of the most suitable animal models for Mycobacterium tuberculosis (M. tb) infection since it shows similarities to pulmonary infection in…”
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17
Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms
Published in The Journal of immunology (1950) (15-07-2013)“…Macrophages in granulomas are both antimycobacterial effector and host cell for Mycobacterium tuberculosis, yet basic aspects of macrophage diversity and…”
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18
A Rapid Assessing Method of Drug Susceptibility Using Flow Cytometry for Mycobacterium tuberculosis Isolates Resistant to Isoniazid, Rifampin, and Ethambutol
Published in Tuberculosis and respiratory diseases (01-07-2022)“…Background: The current conventional drug susceptibility test (DST) for Mycobacterium tuberculosis (Mtb) takes several weeks of incubation to obtain results…”
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19
Inhibition of allergic airways inflammation and airway hyperresponsiveness in mice by dexamethasone: Role of eosinophils, IL-5, eotaxin, and IL-13
Published in Journal of allergy and clinical immunology (01-05-2003)“…Background: Glucocorticoids inhibit allergen-induced airway eosinophilia and airway hyperresponsiveness (AHR). Whether glucocorticoids mediate their effects on…”
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20
Nitric oxide and protein nitration are eosinophil dependent in allergen-challenged mice
Published in American journal of respiratory and critical care medicine (01-04-2001)“…To explore the possible role of eosinophils in NO-mediated tissue injury, we studied a murine model of allergic asthma. Male A/J mice were sensitized and…”
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