Search Results - "Eulenburg, V."

GlyT1 encephalopathy: Characterization of presumably disease causing GlyT1 mutations by Hauf, K., Barsch, L., Bauer, D., Buchert, R., Armbruster, A., Frauenfeld, L., Grasshoff, U., Eulenburg, V.

“…Glycine constitutes a major inhibitory neurotransmitter predominantly in caudal regions of the CNS. The extracellular glycine concentration is regulated…”
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S.28.01 Glycine transporters: essential regulators of synaptic transmission by Eulenburg, V

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EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction by Mielenz, D, Reichel, M, Jia, T, Quinlan, E B, Stöckl, T, Mettang, M, Zilske, D, Kirmizi-Alsan, E, Schönberger, P, Praetner, M, Huber, S E, Amato, D, Schwarz, M, Purohit, P, Brachs, S, Spranger, J, Hess, A, Büttner, C, Ekici, A B, Perez-Branguli, F, Winner, B, Rauschenberger, V, Banaschewski, T, Bokde, A L W, Büchel, C, Conrod, P J, Desrivières, S, Flor, H, Frouin, V, Gallinat, J, Garavan, H, Gowland, P, Heinz, A, Martinot, J-L, Lemaitre, H, Nees, F, Paus, T, Smolka, M N, Schambony, A, Bäuerle, T, Eulenburg, V, Alzheimer, C, Lourdusamy, A, Schumann, G, Müller, C P

“…In many societies, the majority of adults regularly consume alcohol. However, only a small proportion develops alcohol addiction. Individuals at risk often…”
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Glycine transporters: essential regulators of synaptic transmission by Betz, H, Gomeza, J, Armsen, W, Scholze, P, Eulenburg, V

“…Glycine is a major inhibitory neurotransmitter in the mammalian CNS (central nervous system). Glycinergic neurotransmission is terminated by the uptake of…”
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Conditional deletion of Cadherin 13 perturbs Golgi cells and disrupts social and cognitive behaviors by Tantra, M., Guo, L., Kim, J., Zainolabidin, N., Eulenburg, V., Augustine, G. J., Chen, A. I.

“…Inhibitory interneurons mediate the gating of synaptic transmission and modulate the activities of neural circuits. Disruption of the function of inhibitory…”
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Lessons from the knocked-out glycine transporters by Gomeza, J, Armsen, W, Betz, H, Eulenburg, V

“…Glycine has multiple neurotransmitter functions in the central nervous system (CNS). In the spinal cord and brainstem of vertebrates, it serves as a major…”
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Glycine transporters: essential regulators of neurotransmission by Eulenburg, Volker, Armsen, Wencke, Betz, Heinrich, Gomeza, Jesús

“…Glycine has important neurotransmitter functions at inhibitory and excitatory synapses in the vertebrate central nervous system. The effective synaptic…”
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The lidocaine metabolite N-ethylglycine has antinociceptive effects in experimental inflammatory and neuropathic pain by Werdehausen, Robert, Mittnacht, Sebastian, Bee, Lucy A., Minett, Michael S., Armbruster, Anja, Bauer, Inge, Wood, John N., Hermanns, Henning, Eulenburg, Volker

“…Glycine transporter 1 (GlyT1) plays a crucial role in regulating extracellular glycine concentrations and might thereby constitute a new drug target for the…”
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Deficit in acoustic signal‐in‐noise detection in glycine receptor α3 subunit knockout mice by Tziridis, Konstantin, Buerbank, Stefanie, Eulenburg, Volker, Dlugaiczyk, Julia, Schulze, Holger, Herman, James

“…Hearing is an essential sense for communication in animals and humans. Normal function of the cochlea of higher vertebrates relies on a fine‐tuned interplay of…”
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Inactivation of the Glycine Transporter 1 Gene Discloses Vital Role of Glial Glycine Uptake in Glycinergic Inhibition by Gomeza, Jesús, Hülsmann, Swen, Ohno, Koji, Eulenburg, Volker, Szöke, Katalin, Richter, Diethelm, Betz, Heinrich

“…The glycine transporter subtype 1 (GlyT1) is widely expressed in astroglial cells throughout the mammalian central nervous system and has been implicated in…”
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Deletion of the Mouse Glycine Transporter 2 Results in a Hyperekplexia Phenotype and Postnatal Lethality by Gomeza, Jesús, Ohno, Koji, Hülsmann, Swen, Armsen, Wencke, Eulenburg, Volker, Richter, Diethelm W, Laube, Bodo, Betz, Heinrich

“…The glycine transporter subtype 2 (GlyT2) is localized in the axon terminals of glycinergic neurons. Mice deficient in GlyT2 are normal at birth but during the…”
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Lidocaine Metabolites Inhibit Glycine Transporter 1: A Novel Mechanism for the Analgesic Action of Systemic Lidocaine? by WERDEHAUSEN, Robert, KREMER, David, BRANDENBURGER, Timo, SCHLÖSSER, Lukas, JADASZ, Janusz, KURY, Patrick, BAUER, Inge, ARAGON, Carmen, EULENBURG, Volker, HERMANNS, Henning

“…Lidocaine exerts antinociceptive effects when applied systemically. The mechanisms are not fully understood but glycinergic mechanisms might be involved. The…”
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Collybistin is required for both the formation and maintenance of GABAergic postsynapses in the hippocampus by Papadopoulos, Theofilos, Eulenburg, Volker, Reddy-Alla, Suneel, Mansuy, Isabelle M., Li, Yuqing, Betz, Heinrich

“…Collybistin (Cb) is a brain-specific guanine nucleotide exchange factor, which interacts with the inhibitory receptor anchoring protein gephyrin. In the…”
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The C-terminal PDZ-ligand motif of the neuronal glycine transporter GlyT2 is required for efficient synaptic localization by Armsen, Wencke, Himmel, Bettina, Betz, Heinrich, Eulenburg, Volker

“…The neuronal glycine transporter 2 (GlyT2) belongs to the large SLC6 family of Na +/Cl −-dependent neurotransmitter transporters. At its extreme C-terminus,…”
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Mutations within the human GLYT2 ( SLC6A5) gene associated with hyperekplexia by Eulenburg, Volker, Becker, Kristina, Gomeza, Jesús, Schmitt, Bernhard, Becker, Cord-Michael, Betz, Heinrich

“…Hereditary hyperekplexia is a neuromotor disorder characterized by exaggerated startle reflexes and muscle stiffness in the neonate. The disease has been…”
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The adenomatous polyposis coli-protein (APC) interacts with the protein tyrosine phosphatase PTP-BL via an alternatively spliced PDZ domain by ERDMANN, K. S, KUHLMANN, J, LESSMANN, V, HERRMANN, L, EULENBURG, V, MÜLLER, O, HEUMANN, R

“…Mutations of the tumor suppressor protein APC (Adenomatous Polyposis Coli) are linked to familiar and sporadic human colon cancer. Here we describe a novel…”
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Semaphorin4F interacts with the synapse‐associated protein SAP90/PSD‐95 by Schultze, Wiebke, Eulenburg, Volker, Lessmann, Volkmar, Herrmann, Lutz, Dittmar, Thomas, Gundelfinger, Eckart D., Heumann, Rolf, Erdmann, Kai S.

“…Semaphorins are a family of secreted and membrane‐associated proteins involved in growth cone guidance during development. Here, we describe the interaction of…”
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