Search Results - "Eulalia Valle-Garay"
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No gender differences in the 24-month course of non-invasive liver fibrosis markers after DAA therapy in HCV-mono and HCV/HIV-coinfected patients
Published in Scientific reports (29-03-2024)“…Untreated HCV mono and HCV/HIV coinfected women have lower degrees of liver fibrosis (LF) compared to men. Direct acting antiviral (DAA) therapy attains viral…”
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The N125S polymorphism in the cathepsin G gene (rs45567233) is associated with susceptibility to osteomyelitis in a Spanish population
Published in PloS one (24-10-2019)“…Osteomyelitis is a bone infection, most often caused by Staphylococcus aureus, in which neutrophils play a key role. Cathepsin G (CTSG) is a bactericidal…”
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IL-1 β gene (+3954 C/T, exon 5, rs1143634) and NOS2 (exon 22) polymorphisms associate with early aseptic loosening of arthroplasties
Published in Scientific reports (01-11-2022)“…Aseptic prosthetic loosening (APL) and prosthetic joint infections (PJI) are frequent complications of hip and knee implants. Polymorphisms of cytokines and…”
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24-month decline of non-invasive liver fibrosis markers in HCV-mono and HCV/HIV coinfection after direct-acting antiviral therapy
Published in Scientific reports (09-03-2022)“…Long term liver fibrosis (LF) changes and their best -monitoring non-invasive markers (NILFM) after effective anti-HCV DAA therapy are little- known…”
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A functional polymorphism in MMP1 could influence osteomyelitis development
Published in Journal of bone and mineral research (01-04-2010)“…Osteomyelitis (OM) is a bone infection characterized by necrosis and new formation of bone. Because matrix metalloproteases (MMPs) play an important role in…”
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The N125S polymorphism in the cathepsin G gene
Published in PloS one (24-10-2019)“…Background Osteomyelitis is a bone infection, most often caused by Staphylococcus aureus, in which neutrophils play a key role. Cathepsin G (CTSG) is a…”
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The () polymorphism could protect against development of severe sepsis
Published in Innate immunity (London, England) (01-07-2021)“…Primary responses in sepsis-mediated inflammation are regulated by pro-inflammatory cytokines. Variations in the cytokine genes might modify their…”
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The TNF-α (–238 G/A) polymorphism could protect against development of severe sepsis
Published in Innate immunity (London, England) (01-07-2021)“…Primary responses in sepsis-mediated inflammation are regulated by pro-inflammatory cytokines. Variations in the cytokine genes might modify their…”
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Role of plasma matrix-metalloproteases (MMPs) and their polymorphisms (SNPs) in sepsis development and outcome in ICU patients
Published in Scientific reports (16-05-2014)“…Matrix-metalloproteases (MMPs) and their tissue-inhibitors (TIMPs), modulated by different single nucleotide polymorphisms (SNPs), are critical in sepsis…”
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205. IL-1 β gene (+3954C/T, exon 5, rs 1143634 ) and NOS2 (exon 22) polymorphisms associate with early aseptic loosening of hip and knee arthroplasties but not with implants infection
Published in Open forum infectious diseases (15-12-2022)“…Abstract Background Aseptic prosthetic loosening (APL) and prosthetic joint infections (PJI) are frequent complications of hip and knee implants. Polymorphisms…”
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tPA Alu (I/D) Polymorphism Associates With Bacterial Osteomyelitis
Published in The Journal of infectious diseases (15-07-2013)“…Background. Coagulation and fibrinolysis are important in infections and systemic inflammatory response syndrome. Polymorphisms in plasminogen activator…”
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Can antiretroviral therapy be tailored to each human immunodeficiency virus-infected individual? Role of pharmacogenomics
Published in World journal of virology (12-08-2015)“…Pharmacogenetics refers to the effect of single nucleotide polymorphisms (SNPs) within human genes on drug therapy outcome. Its study might help clinicians to…”
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Involvement of the LPS-LPB-CD14-MD2-TLR4 inflammation pathway in HIV-1/HAART-associated lipodystrophy syndrome (HALS)
Published in Journal of antimicrobial chemotherapy (01-06-2014)“…Objectives A relationship between obesity and intestinal bacterial translocation has been reported. Very little information is available with respect to the…”
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Endothelial (NOS3 E298D) and inducible (NOS2 exon 22) nitric oxide synthase polymorphisms, as well as plasma NOx, influence sepsis development
Published in Nitric oxide (15-11-2014)“…•NOS3 (E298D) and NOS2A (exon 22) SNPs associated with sepsis development.•NOS3 (E298D) SNP T allele septic carriers showed increased plasma NOx levels…”
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Matrix metalloproteases and their tissue inhibitors in non-alcoholic liver fibrosis of human immunodeficiency virus-infected patients
Published in World journal of virology (12-05-2017)“…To investigate the relationships among diverse metalloproteases (MMPs) and their tissue inhibitors (TIMPs) and non-alcoholic liver fibrosis in human…”
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The MMP1 (-16071G/2G) single nucleotide polymorphism associates with the HAART-related lipodystrophic syndrome
Published in AIDS (London) (23-10-2010)“…Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are involved in extracellular matrix remodelling and adipocyte differentiation and are…”
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IL-1β (+3954C/T) polymorphism could protect human immunodeficiency virus (HIV)-infected patients on highly active antiretroviral treatment (HAART) against lipodystrophic syndrome
Published in Genetics in medicine (01-03-2008)“…To evaluate the impact of acquired and inherited factors on the development of lipodystrophic syndrome in patients on highly active antiretroviral therapy. Two…”
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Autoregulation mechanism of human neutrophil apoptosis during bacterial infection
Published in Molecular immunology (01-04-2008)“…Neutrophils (PMN), potent phagocytes, are the first line of the host immune defence against microorganisms, especially bacteria. Their half-life is very short…”
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Bax gene G(-248)A promoter polymorphism is associated with increased lifespan of the neutrophils of patients with osteomyelitis
Published in Genetics in medicine (01-04-2007)“…Patients with osteomyelitis have a decreased rate of spontaneous apoptosis of their peripheral blood neutrophils. The G(-248)A polymorphism in the promoter…”
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