Search Results - "Eugenin, E A"
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Pannexin1 hemichannels are critical for HIV infection of human primary CD4+ T lymphocytes
Published in Journal of leukocyte biology (01-09-2013)“…Pannexin‐1 hemichannels as key regulators of HIV infection and replication in human T lymphocytes. HIV is a major public health issue, and infection of CD4+ T…”
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MCP‐1 (CCL2) protects human neurons and astrocytes from NMDA or HIV‐tat‐induced apoptosis
Published in Journal of neurochemistry (01-06-2003)“…Acquired immunodeficiency syndrome (AIDS)‐associated dementia is often characterized by chronic inflammation, with infected macrophage infiltration of the CNS…”
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HIV tat and neurotoxicity
Published in Microbes and infection (01-04-2006)“…HIV tat is the transactivator of HIV-1, supporting efficient viral replication by stabilizing the transcription of viral genes. Tat can be released from…”
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Myelin basic protein induces inflammatory mediators from primary human endothelial cells and blood-brain barrier disruption: implications for the pathogenesis of multiple sclerosis
Published in Neuropathology and applied neurobiology (01-04-2013)“…T. G. D'Aversa, E. A. Eugenin, L. Lopez and J. W. Berman (2013) Neuropathology and Applied Neurobiology39, 270–283 Myelin basic protein induces inflammatory…”
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N-cadherin regulates mammary tumor cell migration through Akt3 suppression
Published in Oncogene (24-01-2013)“…N-cadherin is a cell–cell adhesion molecule that plays a role in breast cancer metastasis. Here, we show that in vivo expression of N-cadherin in the PyMT…”
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p21CIP1 mediates reciprocal switching between proliferation and invasion during metastasis
Published in Oncogene (02-05-2013)“…Cell proliferation and invasion are critical for malignant progression, yet how these processes relate to each other and whether they regulate one another…”
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Chemokine-dependent mechanisms of leukocyte trafficking across a model of the blood–brain barrier
Published in Methods (San Diego, Calif.) (01-04-2003)“…Leukocyte transmigration across the blood–brain barrier (BBB) is a multistep process that can be mediated by chemokines. These low-molecular-weight…”
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Microglia at Brain Stab Wounds Express Connexin 43 and in vitro Form Functional Gap Junctions after Treatment with Interferon-γ and Tumor Necrosis Factor-α
Published in Proceedings of the National Academy of Sciences - PNAS (27-03-2001)“…Gap junctional communication between microglia was investigated at rat brain stab wounds and in primary cultures of rat and mouse cells. Under resting…”
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Shedding of PECAM-1 during HIV infection: a potential role for soluble PECAM-1 in the pathogenesis of NeuroAIDS
Published in Journal of leukocyte biology (01-03-2006)“…Human immunodeficiency virus (HIV) infection is characterized by viral entry into the central nervous system (CNS), which is mediated, in part, by the…”
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Human immunodeficiency virus infection of human astrocytes disrupts blood-brain barrier integrity by a gap junction-dependent mechanism
Published in The Journal of neuroscience (29-06-2011)“…HIV infection of the CNS is an early event after primary infection, resulting in neurological complications in a significant number of individuals despite…”
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NeuroAIDS: Contributions of the human immunodeficiency virus-1 proteins tat and gp120 as well as CD40 to microglial activation
Published in Journal of neuroscience research (01-08-2005)“…Microglia are the resident phagocytes of the brain and are an important source of proinflammatory mediators. Human immunodeficiency virus (HIV)‐1 infects the…”
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Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: A potential mechanism for intercellular HIV trafficking
Published in Cellular immunology (01-01-2009)“…Cell to cell communication is essential for the organization/coordination of multicellular systems and cellular development. Cellular communication is mediated…”
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Metabolic Inhibition Induces Opening of Unapposed Connexin 43 Gap Junction Hemichannels and Reduces Gap Junctional Communication in Cortical Astrocytes in Culture
Published in Proceedings of the National Academy of Sciences - PNAS (08-01-2002)“…Rat cortical astrocytes in pure culture are functionally coupled to neighboring cells via connexin (Cx) 43 gap junctions under ordinary conditions. Small…”
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TNF-alpha plus IFN-gamma induce connexin43 expression and formation of gap junctions between human monocytes/macrophages that enhance physiological responses
Published in The Journal of immunology (1950) (01-02-2003)“…In this work, the effects of bacterial LPS, TNF-alpha, and IFN-gamma on gap junctional communication (dye coupling) and on the expression of connexin43…”
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Differences in NMDA Receptor Expression During Human Development Determine the Response of Neurons to HIV-Tat-mediated Neurotoxicity
Published in Neurotoxicity research (01-01-2011)“…HIV infection of the CNS can result in neurologic dysfunction in a significant number of infected individuals. NeuroAIDS is characterized by neuronal injury…”
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Gap junctions in cells of the immune system: structure, regulation and possible functional roles
Published in Brazilian journal of medical and biological research (01-04-2000)“…Gap junction channels are sites of cytoplasmic communication between contacting cells. In vertebrates, they consist of protein subunits denoted connexins (Cxs)…”
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Regulation of glycogen content in rat pineal gland by norepinephrine
Published in Brain research (20-06-1997)“…In the rat pineal gland the glycogen stores were cytochemically localized in astrocytes and pinealocytes. Moreover, it was found that norepinephrine (NE)…”
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Gap junctional communication coordinates vasopressin-induced glycogenolysis in rat hepatocytes
Published in The American journal of physiology (01-06-1998)“…Because hepatocytes communicate via gap junctions, it has been proposed that Ca2+ waves propagate through this pathway and in the process activate…”
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Human Immunodeficiency Virus (HIV) Infection of Human Macrophages Is Increased by Dopamine: A Bridge between HIV-Associated Neurologic Disorders and Drug Abuse
Published in The American journal of pathology (01-09-2009)“…The prevalence of human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND) that result from HIV infection of the central nervous system is…”
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Human Immunodeficiency Virus (HIV) Infects Human Arterial Smooth Muscle Cells in Vivo and in Vitro: Implications for the Pathogenesis of HIV-Mediated Vascular Disease
Published in The American journal of pathology (01-04-2008)“…Human immunodeficiency virus (HIV) infection is associated with accelerated atherosclerosis and vasculopathy, although the mechanisms underlying these findings…”
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