Search Results - "Eugen Petcu"
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The Cyclin-Dependent Kinase 5 Inhibitor Peptide Inhibits Herpes Simplex Virus Type 1 Replication
Published in Scientific reports (04-02-2019)“…In order to evaluate the influence of CDK5 inhibitory peptide (CIP) on Human alphaherpesvirus 1 (HSV-1) replication, we constructed two recombinant…”
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2
Dietary habits, lifestyle factors and neurodegenerative diseases
Published in Neural regeneration research (01-03-2020)“…Worldwide stroke is increasing in parallel with modernization, changes in lifestyle, and the growing elderly population. Our review is focused on the link…”
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Ageing as a risk factor for cerebral ischemia: Underlying mechanisms and therapy in animal models and in the clinic
Published in Mechanisms of ageing and development (01-09-2020)“…•Age is the only one non-modifiable risk of cerebral ischemia.•Animal models of stroke often ignore age and comorbidities frequently associated with…”
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4
Collagen-Coated Hyperelastic Bone Promotes Osteoblast Adhesion and Proliferation
Published in Materials (01-11-2023)“…Successfully reconstructing bone and restoring its dynamic function represents a significant challenge for medicine. Critical size defects (CSDs), resulting…”
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5
3D printing strategies for peripheral nerve regeneration
Published in Biofabrication (23-03-2018)“…After many decades of biomaterials research for peripheral nerve regeneration, a clinical product (the nerve guide), is emerging as a proven alternative for…”
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Neuroinflammation and comorbidities are frequently ignored factors in CNS pathology
Published in Neural regeneration research (01-09-2015)“…Virtually all drug interventions that have been successful pre-clinically in experimental stroke have failed to prove their efficacy in a dinical setting. This…”
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7
The Role of Oxidative Stress in Etiopathogenesis of Chemotherapy Induced Cognitive Impairment (CICI)-"Chemobrain"
Published in Aging and disease (01-06-2016)“…Chemobrain or chemotherapy induced cognitive impairment (CICI) represents a new clinical syndrome characterised by memory, learning and motor function…”
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Cellular and Molecular Mechanisms Underlying Non-Pharmaceutical Ischemic Stroke Therapy in Aged Subjects
Published in International journal of molecular sciences (29-12-2017)“…The incidence of ischemic stroke in humans increases exponentially above 70 years both in men and women. Comorbidities like diabetes, arterial hypertension or…”
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In vitro pre-vascularisation of tissue-engineered constructs A co-culture perspective
Published in Vascular cell (01-01-2014)“…In vitro pre-vascularization is one of the main vascularization strategies in the tissue engineering field. Culturing cells within a tissue-engineered…”
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10
3D Bio-Printing: An Introduction to a New Approach for Cancer Patients at the Interface of Art and Medicine
Published in Leonardo (Oxford) (01-04-2017)“…Cancer patients require a complex multidisciplinary therapy. In this context the 3D additive biological manufacturing could represent a significant development…”
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11
Bisphosphonate-related osteonecrosis of jaw (BRONJ): diagnostic criteria and possible pathogenic mechanisms of an unexpected anti-angiogenic side effect
Published in Vascular cell (14-01-2013)“…Recently, bisphosphonates (BPs) have been widely used in medical practice as anti-resorptive agents owing to their anti-osteoclatic action. In addition, these…”
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12
Long-term treatment with spermidine increases health span of middle-aged Sprague-Dawley male rats
Published in GeroScience (01-06-2020)“…Let alone calorie restriction, life span extension in higher organisms has proven to be difficult to achieve using simple drugs. Previous studies have shown…”
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13
Photochemically Induced Crosslinking of Tarsal Collagen as a Treatment for Eyelid Laxity: Assessing Potentiality in Animal Tissue
Published in Ophthalmic plastic and reconstructive surgery (01-09-2018)“…An experimental study to demonstrate in animal eyelids that the controlled exposure of excised tarsal plate to ultraviolet-A radiation can induce a…”
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14
The Use of Hydrogels for the Treatment of Bone Osteosarcoma via Localized Drug-Delivery and Tissue Regeneration: A Narrative Review
Published in Gels (25-03-2023)“…Osteosarcoma is a malignant tumor of bone that leads to poor mortality and morbidity. Management of this cancer through conventional methods involves invasive…”
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15
Standardization of negative controls in diagnostic immunohistochemistry: recommendations from the international ad hoc expert panel
Published in Applied immunohistochemistry & molecular morphology (01-04-2014)“…Standardization of controls, both positive and negative controls, is needed for diagnostic immunohistochemistry (dIHC). The use of IHC-negative controls,…”
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16
Extracellular Alpha-Synuclein Promotes a Neuroinhibitory Secretory Phenotype in Astrocytes
Published in Life (Basel, Switzerland) (08-09-2020)“…Multiple system atrophy (MSA) and dementia with Lewy bodies (DLB) are α-synucleinopathies that exhibit widespread astrogliosis as a component of the…”
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Local delivery of hydrogel encapsulated vascular endothelial growth factor for the prevention of medication-related osteonecrosis of the jaw
Published in Scientific reports (03-12-2021)“…The anti-angiogenic effects of bisphosphonates have been hypothesized as one of the major etiologic factors in the development of medication-related…”
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18
Caloric restriction stabilizes body weight and accelerates behavioral recovery in aged rats after focal ischemia
Published in Aging cell (01-12-2017)“…Summary Obesity and hyperinsulinemia are risk factors for stroke. We tested the hypothesis that caloric restriction, which reduces the incidence of age‐related…”
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Medication‐related osteonecrosis of the jaw: A disease of significant importance for older patients
Published in Journal of the American Geriatrics Society (JAGS) (01-08-2023)“…Background Medication‐related osteonecrosis of the jaw (MRONJ) is clinically defined as a non‐healing jawbone ulcerative‐necrotic lesion appearing after dental…”
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20
The effect of bisphosphonates on the endothelial differentiation of mesenchymal stem cells
Published in Scientific reports (09-02-2016)“…The contribution of the local stem cell niche to providing an adequate vascular framework during healing cannot be overemphasized. Bisphosphonates (BPs) are…”
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