Search Results - "Etuk, Annie"

Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia by Ottaviano, Giorgio, Georgiadis, Christos, Gkazi, Soragia Athina, Syed, Farhatullah, Zhan, Hong, Etuk, Annie, Preece, Roland, Chu, Jan, Kubat, Agnieszka, Adams, Stuart, Veys, Paul, Vora, Ajay, Rao, Kanchan, Qasim, Waseem

“…Genome editing of allogeneic T cells can provide "off-the-shelf" alternatives to autologous chimeric antigen receptor (CAR) T cell therapies. Disruption of T…”
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Umbilical cord blood T cells can be isolated and enriched by CD62L selection for use in 'off the shelf' chimeric antigen receptor T-cell therapies to widen transplant options by Georgiadis, Christos, Nickolay, Lauren, Syed, Farhatullah, Zhan, Hong, Gkazi, Soragia Athina, Etuk, Annie, Abramowski-Mock, Ulrike, Preece, Roland, Cuber, Piotr, Adams, Stuart, Ottaviano, Giorgio, Qasim, Waseem

“…Umbilical cord blood (UCB) T cells exhibit distinct naive ontogenetic profiles and may be an attractive source of starting cells for the production of chimeric…”
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Base-Edited CAR7 T Cells for Relapsed T-Cell Acute Lymphoblastic Leukemia by Chiesa, Robert, Georgiadis, Christos, Syed, Farhatullah, Zhan, Hong, Etuk, Annie, Gkazi, Soragia Athina, Preece, Roland, Ottaviano, Giorgio, Braybrook, Toni, Chu, Jan, Kubat, Agnieszka, Adams, Stuart, Thomas, Rebecca, Gilmour, Kimberly, O’Connor, David, Vora, Ajay, Qasim, Waseem

“…Three patients with T-cell ALL were treated with allogeneic CAR T cells that were base-edited to prevent CAR T-cell fratricide and graft-versus-host disease…”
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Universal' Fratricide-Resistant CAR T Cells Against T Cell Leukemia Generated By Coupled & Uncoupled Deamination Mediated Base Editing by Georgiadis, Christos, Rasaiyaah, Jane, Gkazi, Soragia Athina, Preece, Roland, Etuk, Annie, Christi, Abraham, Qasim, Waseem

“…Chimeric antigen receptor (CAR) T cell approaches to target T cell malignancies have been hampered by the fundamental issue of ‘T v T’ fratricide when T…”
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Single and Combinational Multiplex Base-Edited 'Universal' CAR T Cells in a Humanised Model of Primary CD7+CD33+ AML by Kloos, Arnold, Georgiadis, Christos, Etuk, Annie, Gkazi, Soragia Athina, Syed, Farhatullah, Braybrook, Toni, Zhan, Hong, Kadirkamanathan, Renuka, Kattre, Nadine, Görlich, Kerstin, Fangmann, Thomas, Schambach, Axel, Sauer, Martin G., Heuser, Michael, Qasim, Waseem

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TT52CAR19: Phase 1 Trial of CRISPR/Cas9 Edited Allogeneic CAR19 T Cells for Paediatric Relapsed/Refractory B-ALL by Ottaviano, Giorgio, Georgiadis, Christos, Syed, Farhatullah, Gkazi, Soragia Athina, Zhan, Hong, Etuk, Annie, Chu, Jan, Pinner, Danielle, Inglott, Sarah, Gilmour, Kimberly, Adams, Stuart, Kricke, Susanne, Izotova, Natalia, Ladon, Dariusz, Kubat, Agnieszka, Veys, Paul, Vora, Ajay, Rao, Kanchan, Qasim, Waseem

“…Background ‘Off-the-shelf’ CAR T cell therapies are being investigated as alternatives to autologous CAR therapy, and can be generated using genome editing…”
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Tvt CAR7: Phase 1 Clinical Trial of Base-Edited "Universal” CAR7 T Cells for Paediatric Relapsed/Refractory T-ALL by Chiesa, Robert, Georgiadis, Christos, Ottaviano, Giorgio, Syed, Farhatullah, Braybrook, Toni, Etuk, Annie, Zhan, Hong, Gkazi, Soragia Athina, Preece, Roland, Adams, Stuart, Thomas, Rebecca, Awuah, Arnold, Gilmour, Kimberly, Mhaldien, Lana, Chu, Jan, Pinner, Danielle, Kubat, Agnieszka, Veys, Paul, Rao, Kanchan, Lucchini, Giovanna, O'Connor, David, Vora, Ajay, Qasim, Waseem

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