Search Results - "Ettorre, Luciano"
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Formulation Development of a COVID-19 Recombinant Spike Protein-Based Vaccine
Published in Vaccines (Basel) (23-07-2024)“…The purpose of this study was to develop a formulation for a recombinant prefusion spike protein vaccine against SARS-CoV-2. It was found that the spike…”
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Epitope Profiling of Diphtheria Toxoid Provides Enhanced Monitoring for Consistency Testing during Manufacturing Process Changes
Published in Vaccines (Basel) (13-05-2022)“…In the vaccine industry, multiple physicochemical, immunological, and analytical methods are applied throughout the manufacturing process to characterize and…”
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Hydrogen–Deuterium Exchange Epitope Mapping Reveals Distinct Neutralizing Mechanisms for Two Monoclonal Antibodies against Diphtheria Toxin
Published in Biochemistry (Easton) (12-02-2019)“…The diphtheria toxoid (DT) antigen is one of the major components in pediatric and booster combination vaccines and is known to raise a protective humoral…”
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Replacing the in vivo toxin challenge test with an in vitro assay for assessment of potency for diphtheria toxoid containing vaccines
Published in Biologicals (01-11-2020)“…Replacement of the potency tests for diphtheria vaccines is a high priority for the international initiative to reduce, refine, and replace animal use in…”
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In vitro assessment of biological activity and stability of the ALVAC-HIV vaccine
Published in Vaccine (05-09-2018)“…•High-throughput biological activity assay for characterization of ALVAC-HIV vaccine.•Results correlate with infectious titer assay, the vaccine quantitative…”
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Plasmid DNA Encoding the Respiratory Syncytial Virus G Protein Is a Promising Vaccine Candidate
Published in Virology (New York, N.Y.) (30-03-2000)“…Respiratory syncytial virus (RSV) remains a major cause of severe respiratory diseases in infants, young children, and the elderly. However, development of a…”
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