Disease due to Mycobacterium kansasii in the Czech Republic: 1984-89

Endemic area of North Moravia, Czech Republic. Evaluate the incidence of human disease due to Mycobacterium kansasii. The follow-up of some bacteriological and clinical features. A retrospective analysis of M. kansasii patients. M. kansasii was isolated from the sputum, tissue and other specimens ob...

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Bibliographic Details
Published in:	Tubercle and lung disease Vol. 76; no. 3; p. 205
Main Authors:	Kaustová, J, Chmelík, M, Ettlová, D, Hudec, V, Lazarová, H, Richtrová, S
Format:	Journal Article
Language:	English
Published:	Scotland 1995
Subjects:	Anti-Bacterial Agents Antitubercular Agents - therapeutic use Czech Republic - epidemiology Drug Resistance, Microbial Drug Therapy, Combination - therapeutic use Female Humans Male Middle Aged Mycobacterium Infections, Nontuberculous - complications Mycobacterium Infections, Nontuberculous - epidemiology Mycobacterium Infections, Nontuberculous - microbiology Nontuberculous Mycobacteria - isolation & purification Retrospective Studies Rifampin - therapeutic use Tuberculosis, Pulmonary - complications Czech Republic
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Summary:	Endemic area of North Moravia, Czech Republic. Evaluate the incidence of human disease due to Mycobacterium kansasii. The follow-up of some bacteriological and clinical features. A retrospective analysis of M. kansasii patients. M. kansasii was isolated from the sputum, tissue and other specimens obtained from 650 persons during the period 1984-89. In only 471 of them was this mycobacterium deemed to be the causative agent, predominantly of lung disease. The most typical radiographic finding in these patients was lung infiltration and/or thin-walled cavity. As in previous years the highest incidence of disease remains in an endemic area of North Moravia. The effects of treatment in follow-up patients were influenced not only by the antituberculosis regimen but also by a high frequency of associated diseases. Sputum conversion within 30 days was not affected by the presence or absence of a cavity. Authors consider water to be the source of infection.
ISSN:	0962-8479
DOI:	10.1016/s0962-8479(05)80006-1