Search Results - "Etter, Jonathan"

The cardiovascular disease burden of non-traumatic fractures for adults with and without cerebral palsy by Whitney, Daniel G., Bell, Sarah, Etter, Jonathan P., Prisby, Rhonda D.

“…Individuals with cerebral palsy (CP) are vulnerable to non-trauma fracture (NTFx) and have an elevated burden of cardiovascular disease (CVD) related morbidity…”
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Anticancer activity and SAR studies of substituted 1,4-naphthoquinones by Bhasin, Deepak, Chettiar, Somsundaram N., Etter, Jonathan P., Mok, May, Li, Pui-Kai

“…In this paper, we report the structure–activity relationship studies of substituted 1,4-naphthoquinones for its anticancer properties. 1,4-Naphthoquinone,…”
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Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines by Bill, Matthew A, Nicholas, Courtney, Mace, Thomas A, Etter, Jonathan P, Li, Chenglong, Schwartz, Eric B, Fuchs, James R, Young, Gregory S, Lin, Li, Lin, Jiayuh, He, Lei, Phelps, Mitch, Li, Pui-Kai, Lesinski, Gregory B

“…The Janus kinase-2 (Jak2)-signal transducer and activator of transcription-3 (STAT3) pathway is critical for promoting an oncogenic and metastatic phenotype in…”
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First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy by Sen, Malabika, Thomas, Sufi M, Kim, Seungwon, Yeh, Joanne I, Ferris, Robert L, Johnson, Jonas T, Duvvuri, Umamaheswar, Lee, Jessica, Sahu, Nivedita, Joyce, Sonali, Freilino, Maria L, Shi, Haibin, Li, Changyou, Ly, Danith, Rapireddy, Srinivas, Etter, Jonathan P, Li, Pui-Kai, Wang, Lin, Chiosea, Simion, Seethala, Raja R, Gooding, William E, Chen, Xiaomin, Kaminski, Naftali, Pandit, Kusum, Johnson, Daniel E, Grandis, Jennifer R

“…Despite evidence implicating transcription factors, including STAT3, in oncogenesis, these proteins have been regarded as "undruggable." We developed a decoy…”
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Antiproliferative activities and SAR studies of substituted anthraquinones and 1,4-naphthoquinones by Bhasin, Deepak, Etter, Jonathan P., Chettiar, Somsundaram N., Mok, May, Li, Pui-Kai

“…STAT3 is constitutively active in a large variety of cancers. The search for STAT3 inhibitors led to the discoveries of LLLs 3 and 12, which are substituted…”
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The respiratory disease burden of non-traumatic fractures for adults with cerebral palsy by Etter, Jonathan P., Kannikeswaran, Sanjana, Hurvitz, Edward A., Peterson, Mark D., Caird, Michelle S., Jepsen, Karl J., Whitney, Daniel G.

“…Individuals with cerebral palsy (CP) are vulnerable to non-trauma fracture (NTFx) and premature mortality due to respiratory disease (RD); however, very little…”
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Structure-activity relationship studies of curcumin analogues by FUCHS, James R, PANDIT, Bulbul, BHASIN, Deepak, ETTER, Jonathan P, REGAN, Nicholas, ABDELHAMID, Dalia, CHENGLONG LI, LIN, Jiayuh, LI, Pui-Kai

“…Two series of curcumin analogues, a total of twenty-four compounds, were synthesized and evaluated. The most potent compound, compound 23, showed potent growth…”
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Design, synthesis and biological studies of novel tubulin inhibitors by Sun, Yanjun, Pandit, Bulbul, Chettiar, Somsundaram N., Etter, Jonathan P., Lewis, Andrew, Johnsamuel, Jayasekar, Li, Pui-Kai

“…A series of compounds originally derived from the vascular endothelial growth factor receptor tyrosine kinase inhibitor, SU5416, were synthesized and…”
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Structure–activity relationship studies of thalidomide analogs with a taxol-like mode of action by Pandit, Bulbul, Hu, Zhigen, Chettiar, Somsundaram N., Zink, Jennifer, Xiao, Zili, Etter, Jonathan P., Bhasin, Deepak, Li, Pui-Kai

“…Anti-microtubule agents such as paclitaxel and docetaxel have played an important role in the treatment of cancer for many years. Recently, a small molecule…”
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Innate and adaptive immune activation in the brain of MPS IIIB mouse model by DiRosario, Julianne, Divers, Erin, Wang, Chuansong, Etter, Jonathan, Charrier, Alyssa, Jukkola, Peter, Auer, Herbert, Best, Victoria, Newsom, David L., McCarty, Douglas M., Fu, Haiyan

“…Mucopolysaccharidosis (MPS) IIIB is a lysosomal storage disease with severe neurological manifestations due to α‐N‐acetylglucosaminidase (NaGlu) deficiency…”
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Eyelash migration into a clear corneal incision following cataract surgery by Etter, Jonathan, MD, Kim, Terry, MD

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Efficiently mining Adverse Event Reporting System for multiple drug interactions by Xiang, Yang, Albin, Aaron, Ren, Kaiyu, Zhang, Pengyue, Etter, Jonathan P, Lin, Simon, Li, Lang

“…Efficiently mining multiple drug interactions and reactions from Adverse Event Reporting System (AERS) is a challenging problem which has not been sufficiently…”
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Corneal wound integrity and architecture after phacoemulsification: Comparative analysis of corneal wounds created by silicon and steel blades by Etter, Jonathan, MD, Berdahl, John, MD, Jun, Bokkwan, MD, Caldwell, Matthew, MD, Kim, Terry, MD

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High Prevalence of Plateau Iris Configuration in Family Members of Patients With Plateau Iris Syndrome by Etter, Jonathan R, Affel, Elizabeth L, Rhee, Douglas J

“…PURPOSEThe purpose of the study was to ascertain the prevalence of plateau iris syndrome in the first-degree relatives of those patients affected with plateau…”
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Ectopic Brain in the Orbit Presenting as Disc Edema in an Adult by Price, Kristina M., Cummings, Thomas J., Etter, Jonathan R., Woodward, Julie A.

“…A 59-year-old man presented with disc edema in the right eye. MRI demonstrated a lesion extending to the orbital apex. The lesion was biopsied and pathology…”
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Strikingly High Myopia in Aland Island Eye Disease by Lai, Wei Chen, Etter, Jonathan, Schechet, Sidney A

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Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors by Kim, Tae-Dong, Fuchs, James R, Schwartz, Eric, Abdelhamid, Dalia, Etter, Jonathan, Berry, William L, Li, Chenglong, Ihnat, Michael A, Li, Pui-Kai, Janknecht, Ralf

“…Colon tumors are a major cause of cancer death, yet their molecular intricacies are not fully understood. We demonstrate that the histone demethylases JMJD2A,…”
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Pars plana vitrectomy and internal limiting membrane peeling in an eye with foveal lipid deposition after focal laser surgery for diabetic macular edema by Etter, Jonathan, Fekrat, Sharon

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Abstract 4502: Synthesis and evaluation of curcumin-like compounds as inhibitors of the JAK/STAT pathway in cancer by Abdelhamid, Dalia, Corcoran, Mike, Etter, Jonathan P., Hu, Sheng, Pandit, Bulbul, Li, Chenglong, Li, Pui-Kai, Fuchs, James R.

“…Curcumin is an attractive lead compound for drug discovery and development. It displays a range of remarkable and diverse biological activities due to its…”
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Femtosecond Keratectomy for Advanced Fungal Keratitis by Etter, Jonathan, Carlson, Alan N.

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