Search Results - "Ettcheto, Miren"
-
1
Metal-based nanoparticles as antimicrobial agents: an overview
Published in Nanomaterials (Basel, Switzerland) (09-02-2020)“…Metal-based nanoparticles have been extensively investigated for a set of biomedical applications. According to the World Health Organization, in addition to…”
Get full text
Journal Article -
2
Memantine for the Treatment of Dementia: A Review on its Current and Future Applications
Published in Journal of Alzheimer's disease (13-03-2018)“…Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the presence in the brain of extracellular amyloid-β protein (Aβ) and intracellular…”
Get more information
Journal Article -
3
Memantine loaded PLGA PEGylated nanoparticles for Alzheimer's disease: in vitro and in vivo characterization
Published in Journal of nanobiotechnology (27-03-2018)“…Memantine, drug approved for moderate to severe Alzheimer's disease, has not shown to be fully effective. In order to solve this issue, polylactic-co-glycolic…”
Get full text
Journal Article -
4
Advanced Formulation Approaches for Ocular Drug Delivery: State-Of-The-Art and Recent Patents
Published in Pharmaceutics (06-09-2019)“…The eye presents extensive perspectives and challenges for drug delivery, mainly because of the extraordinary capacity, intrinsic to this path, for drugs to…”
Get full text
Journal Article -
5
Current Research Therapeutic Strategies for Alzheimer’s Disease Treatment
Published in Neural plasticity (01-01-2016)“…Alzheimer’s disease (AD) currently presents one of the biggest healthcare issues in the developed countries. There is no effective treatment capable of slowing…”
Get full text
Journal Article -
6
Nanomedicine-based technologies and novel biomarkers for the diagnosis and treatment of Alzheimer's disease: from current to future challenges
Published in Journal of nanobiotechnology (29-04-2021)“…Increasing life expectancy has led to an aging population, which has consequently increased the prevalence of dementia. Alzheimer's disease (AD), the most…”
Get full text
Journal Article -
7
Protein tyrosine phosphatase 1B (PTP1B) as a potential therapeutic target for neurological disorders
Published in Biomedicine & pharmacotherapy (01-11-2022)“…Protein tyrosine phosphatase 1B (PTP1B) is a typical member of the PTP family, considered a direct negative regulator of several receptor and…”
Get full text
Journal Article -
8
Epigallocatechin-3-gallate loaded PEGylated-PLGA nanoparticles: A new anti-seizure strategy for temporal lobe epilepsy
Published in Nanomedicine (01-06-2018)“…Temporal lobe epilepsy is the most common type of pharmacoresistant epilepsy in adults. Epigallocatechin-3-gallate has aroused much interest because of its…”
Get full text
Journal Article -
9
Current applications of nanoemulsions in cancer therapeutics
Published in Nanomaterials (Basel, Switzerland) (31-05-2019)“…Nanoemulsions are pharmaceutical formulations composed of particles within a nanometer range. They possess the capacity to encapsulate drugs that are poorly…”
Get full text
Journal Article -
10
Epigallocatechin-3-Gallate (EGCG) Improves Cognitive Deficits Aggravated by an Obesogenic Diet Through Modulation of Unfolded Protein Response in APPswe/PS1dE9 Mice
Published in Molecular neurobiology (01-04-2020)“…Epigallocatechin-3-gallate (EGCG), a catechin found in green tea, has been previously investigated for its neuroprotective effects in vitro and in vivo . In…”
Get full text
Journal Article -
11
From Inhalation to Neurodegeneration: Air Pollution as a Modifiable Risk Factor for Alzheimer's Disease
Published in International journal of molecular sciences (25-06-2024)“…Air pollution, a growing concern for public health, has been linked to various respiratory and cardiovascular diseases. Emerging evidence also suggests a link…”
Get full text
Journal Article -
12
State-of-the-art polymeric nanoparticles as promising therapeutic tools against human bacterial infections
Published in Journal of nanobiotechnology (31-10-2020)“…Infectious diseases kill over 17 million people a year, among which bacterial infections stand out. From all the bacterial infections, tuberculosis, diarrhoea,…”
Get full text
Journal Article -
13
ADAM10 in Alzheimer's disease: Pharmacological modulation by natural compounds and its role as a peripheral marker
Published in Biomedicine & pharmacotherapy (01-05-2019)“…[Display omitted] •APP cleavage by the α-secretase ADAM10 releases the soluble portion sAβPPα and prevents the generation of senile plaques.•Non-amyloidogenic…”
Get full text
Journal Article -
14
Metformin a Potential Pharmacological Strategy in Late Onset Alzheimer’s Disease Treatment
Published in Pharmaceuticals (Basel, Switzerland) (01-09-2021)“…Alzheimer’s disease (AD) is one of the most devastating brain disorders. Currently, there are no effective treatments to stop the disease progression and it is…”
Get full text
Journal Article -
15
Metformin restores cognitive dysfunction and histopathological deficits in an animal model of sporadic Alzheimer's disease
Published in Heliyon (01-07-2023)“…Metformin has been introduced as a neuroprotective agent in recent years. Here we evaluate the therapeutic effects of metformin in sporadic mouse model of…”
Get full text
Journal Article -
16
Lipid Nanoparticles for the Posterior Eye Segment
Published in Pharmaceutics (01-01-2022)“…This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective…”
Get full text
Journal Article -
17
Licochalcone A: A Potential Multitarget Drug for Alzheimer’s Disease Treatment
Published in International journal of molecular sciences (01-09-2023)“…Licochalcone A (Lico-A) is a flavonoid compound derived from the root of the Glycyrrhiza species, a plant commonly used in traditional Chinese medicine. While…”
Get full text
Journal Article -
18
Epilepsy in neurodegenerative diseases: related drugs and molecular pathways
Published in Pharmaceuticals (Basel, Switzerland) (18-10-2021)“…Epilepsy is a chronic disease of the central nervous system characterized by an electrical imbalance in neurons. It is the second most prevalent neurological…”
Get full text
Journal Article -
19
Evaluation of Neuropathological Effects of a High-Fat Diet in a Presymptomatic Alzheimer's Disease Stage in APP/PS1 Mice
Published in Journal of Alzheimer's disease (23-08-2016)“…Alzheimer's disease (AD) is currently an incurable aging-related neurodegenerative disorder. Recent studies give support to the hypotheses that AD should be…”
Get more information
Journal Article -
20
Effects of a High-Fat Diet on Insulin-Related miRNAs in Plasma and Brain Tissue in APPSwe/PS1dE9 and Wild-Type C57BL/6J Mice
Published in Nutrients (26-03-2024)“…Insulin resistance (IR)-related miRNAs have been associated with the development and progression of Alzheimer’s disease (AD). The dietary modulation of these…”
Get full text
Journal Article