Search Results - "Eterovic, Agda K."

Mediators of Glioblastoma Resistance and Invasion during Antivascular Endothelial Growth Factor Therapy by Agda K. Lucio-Eterovic, Yuji Piao, John F. de Groot

“…Purpose: Vascular endothelial growth factor (VEGF) has been identified as a critical regulator of angiogenesis. Currently, several different strategies are…”
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A Population of Heterogeneous Breast Cancer Patient-Derived Xenografts Demonstrate Broad Activity of PARP Inhibitor in BRCA1/2 Wild-Type Tumors by Evans, Kurt W, Yuca, Erkan, Akcakanat, Argun, Scott, Stephen M, Arango, Natalia Paez, Zheng, Xiaofeng, Chen, Ken, Tapia, Coya, Tarco, Emily, Eterovic, Agda K, Black, Dalliah M, Litton, Jennifer K, Yap, Timothy A, Tripathy, Debu, Mills, Gordon B, Meric-Bernstam, Funda

“…Breast cancer patients who do not respond to neoadjuvant therapy have a poor prognosis. There is a pressing need for novel targets and models for preclinical…”
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Gene expression profile analysis of primary glioblastomas and non-neoplastic brain tissue: identification of potential target genes by oligonucleotide microarray and real-time quantitative PCR by Scrideli, Carlos A., Carlotti, Carlos G., Okamoto, Oswaldo K., Andrade, Vanessa S., Cortez, Maria A. A., Motta, Fábio J. N., Lucio-Eterovic, Agda K., Neder, Luciano, Rosemberg, Sérgio, Oba-Shinjo, Sueli M., Marie, Suely K. N., Tone, Luíz G.

“…The prognosis of glioblastomas is still extremely poor and the discovery of novel molecular therapeutic targets can be important to optimize treatment…”
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Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set by Roszik, Jason, Haydu, Lauren E, Hess, Kenneth R, Oba, Junna, Joon, Aron Y, Siroy, Alan E, Karpinets, Tatiana V, Stingo, Francesco C, Baladandayuthapani, Veera, Tetzlaff, Michael T, Wargo, Jennifer A, Chen, Ken, Forget, Marie-Andrée, Haymaker, Cara L, Chen, Jie Qing, Meric-Bernstam, Funda, Eterovic, Agda K, Shaw, Kenna R, Mills, Gordon B, Gershenwald, Jeffrey E, Radvanyi, Laszlo G, Hwu, Patrick, Futreal, P Andrew, Gibbons, Don L, Lazar, Alexander J, Bernatchez, Chantale, Davies, Michael A, Woodman, Scott E

“…While clinical outcomes following immunotherapy have shown an association with tumor mutation load using whole exome sequencing (WES), its clinical…”
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Dynamic clonal remodelling in breast cancer metastases is associated with subtype conversion by Lluch, Ana, González-Angulo, Ana M., Casadevall, David, Eterovic, Agda K., Martínez de Dueñas, Eduardo, Zheng, Xiaofeng, Guerrero-Zotano, Ángel, Liu, Shuying, Pérez, Ramón, Chen, Ken, Chacón, Jose Ignacio, Mills, Gordon B., Antolín, Silvia, Blancas, Isabel, López-Serra, Paula, Carrasco, Eva, Caballero, Rosalía, Prat, Aleix, Rojo, Federico, Gonzalez-Perez, Abel, Meric-Bernstam, Funda, Albanell, Joan

“…Changes in the clinical subtype (CS) and intrinsic subtype (IS) between breast cancer (BC) metastases and corresponding primary tumours have been reported…”
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Detection of breast cancer stem cell gene mutations in circulating free DNA during the evolution of metastases by Liu, Zhe-Bin, Ezzedine, Nader E., Eterovic, Agda K., Ensor, Joe E., Huang, Helen J., Albanell, Joan, Choi, Dong S., Lluch, Ana, Liu, Yi, Rojo, Federico, Wong, Helen, Martínez-Dueñas, Eduardo, Guerrero-Zotano, Ángel, Shao, Zhi-Min, Darcourt, Jorge G., Mills, Gordon B., Dave, Bhuvanesh, Chang, Jenny C.

“…Purpose Limited knowledge exists on the detection of breast cancer stem cell (BCSC)-related mutations in circulating free DNA (cfDNA) from patients with…”
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Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas by Lucio-Eterovic, Agda K B, Cortez, Maria A A, Valera, Elvis T, Motta, Fabio J N, Queiroz, Rosane G P, Machado, Helio R, Carlotti, Jr, Carlos G, Neder, Luciano, Scrideli, Carlos A, Tone, Luiz G

“…Glioblastoma is the most lethal primary malignant brain tumor. Although considerable progress has been made in the treatment of this aggressive tumor, the…”
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Tyrosine Kinase Inhibitor and Immune Checkpoint Inhibitor Responses in KIT-Mutant Metastatic Melanoma by McKean, Meredith, Oba, Junna, Ma, Junsheng, Roth, Katherine G, Wang, Wei-Lien, Macedo, Mariana P., Carapeto, Fernando C.L., Haydu, Lauren E., Siroy, Alan E., Vo, Phuong, Hong, David S., Eterovic, Agda K., Patel, Keyur Pravinchandra, Bassett, Roland L, Grimm, Elizabeth A., Lazar, Alexander J., Woodman, Scott E.

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Functional consequence of the MET-T1010I polymorphism in breast cancer by Liu, Shuying, Meric-Bernstam, Funda, Parinyanitikul, Napa, Wang, Bailiang, Eterovic, Agda K, Zheng, Xiaofeng, Gagea, Mihai, Chavez-MacGregor, Mariana, Ueno, Naoto T, Lei, Xiudong, Zhou, Wanding, Nair, Lakshmy, Tripathy, Debu, Brown, Powel H, Hortobagyi, Gabriel N, Chen, Ken, Mendelsohn, John, Mills, Gordon B, Gonzalez-Angulo, Ana M

“…Major breast cancer predisposition genes, only account for approximately 30% of high-risk breast cancer families and only explain 15% of breast cancer familial…”
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ClinSeK: a targeted variant characterization framework for clinical sequencing by Zhou, Wanding, Zhao, Hao, Chong, Zechen, Mark, Routbort J, Eterovic, Agda K, Meric-Bernstam, Funda, Chen, Ken

“…Applying genomics to patient care demands sensitive, unambiguous and rapid characterization of a known set of clinically relevant variants in patients'…”
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Abstract PD3-6: ConvertHER: Evolution of genomic alterations from primary to metastatic breast cancer by Gonzalez-Angulo, Ana Maria, Lluch, Ana, Eterovic, Agda K, Guerrero, Angel, Zheng, Xiaofeng, Perez, Ramon, Liu, Shuying, Chacón, José I, Chen, Ken, Antolin, Silvia, Mills, Gordon B, Ferrer, Jaime, Burgues, Octavio, Bermejo, Begona, Munoz, Elia, Caballero, Rosalia, Carrasco, Eva, Martinez, Eduardo, Meric-Bernstam, Funda

“…Abstract Background: Changes in breast cancer receptor status over disease progression and treatment have been described to a point that could alter response…”
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Mediators of Glioblastoma Resistance and Invasion during Antivascular Endothelial Growth FactorTherapy by LUCIO-ETEROVIC, Agda K, YUJI PIAO, DE GROOT, John F

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Functional consequence of the MET-T 1010I polymorphism in breast cancer by Liu, Shuying, Meric-Bernstam, Funda, Parinyanitikul, Napa, Wang, Bailiang, Eterovic, Agda K., Zheng, Xiaofeng, Gagea, Mihai, Chavez-MacGregor, Mariana, Ueno, Naoto T., Lei, Xiudong, Zhou, Wanding, Nair, Lakshmy, Tripathy, Debu, Brown, Powel H., Hortobagyi, Gabriel N., Chen, Ken, Mendelsohn, John, Mills, Gordon B., Gonzalez-Angulo, Ana M.

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