Search Results - "Etem, Ebru Onalan"
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Tofacitinib and metformin reduce the dermal thickness and fibrosis in mouse model of systemic sclerosis
Published in Scientific reports (15-02-2022)“…Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway is important in the process of inflammation and fibrosis. The adenosine…”
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Reduction of cryopreservation‐induced structural, functional and molecular damages in ram sperm by hydrated C60 fullerene
Published in Reproduction in domestic animals (01-01-2024)“…This study aimed to investigate the morphological, functional and molecular changes in frozen–thawed ram sperm using an extender containing different…”
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3
Verapamil‐induced ion channel and miRNA expression changes in rat testis and/or spermatozoa may be associated with male infertility
Published in Andrologia (01-11-2020)“…The effect of verapamil, a calcium channel blocker, on male fertility in terms of ion channel and miRNA gene expressions in testis/spermatozoa was evaluated in…”
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Carbamazepine‐induced sperm disorders can be associated with the altered expressions of testicular KCNJ11/miR‐let‐7a and spermatozoal CFTR/miR‐27a
Published in Andrologia (01-03-2021)“…Male infertility is a global health problem, and the underlying molecular mechanisms are not clearly known. Ion channels and microRNAs (miRNAs), known to…”
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5
Ion channel gene expressions in infertile men: A case-control study
Published in International journal of reproductive biomedicine (Yazd, Iran) (01-12-2017)“…Infertility is described as not receiving pregnancy despite unprotected and regular sexual intercourse in a 1 yr period. It is detected by 15% of the couples…”
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Inhibition of TRPC1, TRPM4 and CHRNA6 ion channels ameliorates depression-like behavior in rats
Published in Behavioural brain research (09-04-2022)“…The roles of ion channels, miRNAs and, neurotransmitters in the pathophysiology of major depressive disorder (MDD) are not yet fully elucidated. The current…”
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Carbamazepine-induced renal toxicity may be associated with oxidative stress and apoptosis in male rat
Published in Drug and chemical toxicology (New York, N.Y. 1978) (02-01-2023)“…Carbamazepine (CBZ) is the antiepileptic drug used in epilepsy and some psychiatric disorders. Besides its widely used, many adverse effects have been reported…”
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8
Acid-sensing ion channels (ASICs) influence excitability of stellate neurons in the mouse cochlear nucleus
Published in Journal of Comparative Physiology (01-10-2019)“…Acid-sensing ion channels (ASICs) are voltage-independent and proton-gated channels. In this study, we aimed to test the hypothesis whether ASICs might be…”
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9
TRPM2 mediates distruption of autophagy machinery and correlates with the grade level in prostate cancer
Published in Journal of cancer research and clinical oncology (01-05-2019)“…Purpose Transient receptor potential melastatin 2 (TRPM2), a calcium-permeable ion channel, is shown as a prognostic marker candidate in prostate cancer (PCa)…”
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10
Effects of apelin on reproductive functions: relationship with feeding behavior and energy metabolism
Published in Archives of physiology and biochemistry (01-02-2017)“…Apelin is an adipose tissue derived peptidergic hormone. In this study, 40 male Sprague-Dawley rats were used (four groups; n = 10). Apelin-13 at three…”
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Evaluation of toll-like receptors 2 and 4 polymorphism and intestinal microbiota in children with food allergies
Published in Turkish journal of pediatrics (01-09-2023)“…Background. Mutual regulation between immune system and gut microbiota is achieved through several mechanisms including the engagement of toll-like receptors…”
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Effect of freeze-thawing process on lipid peroxidation, miRNAs, ion channels, apoptosis and global DNA methylation in ram spermatozoa
Published in Reproduction fertility and development (01-11-2021)“…This study was carried out to investigate the effect of the semen freeze-thawing process on the functionality and molecular structure of ram spermatozoa. The…”
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13
Common single nucleotide polymorphisms in the FNDC5 gene and serum irisin levels in acute myocardial infarction
Published in Anatolian journal of cardiology (01-08-2021)“…Acute myocardial infarction (AMI) is the most common type of coronary artery disease. The irisin hormone encoded by the fibronectin type III domain-containing…”
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Analysis of GJB2 (Connexin 26) Mutation in Patients with Congenital Non-Syndromic Sensorineural Hearing Loss
Published in Turkish Archives of Otorhinolaryngology (01-03-2014)“…Objective:This study was performed to investigate the GJB2 (connexin 26) gene mutations that are the most frequent cause of sensorineural deafness in patients…”
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15
Secukinumab and metformin ameliorate dermal fibrosis by decreasing tissue interleukin‐17 levels in bleomycin‐induced dermal fibrosis
Published in International journal of rheumatic diseases (01-06-2021)“…Although the pathogenesis of systemic sclerosis is not exactly known, it is thought that immune activation has prominent roles in pathogenesis. Secukinumab is…”
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Effects of resveratrol on blood homocysteine level, on homocysteine induced oxidative stress, apoptosis and cognitive dysfunctions in rats
Published in Brain research (12-11-2012)“…Abstract We aimed to examine the protective effects of resveratrol against homocysteine induced oxidative stress, apoptosis and cognitive impairment. Rats were…”
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Potential role of melastatin-related transient receptor potential cation channel subfamily M gene expression in the pathogenesis of urinary bladder cancer
Published in Oncology letters (01-12-2016)“…Urinary bladder cancer is one of the most common malignancies of the urinary tract. Ion channels and calcium homeostasis are involved in almost all basic…”
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Potential relationship between BK virus and renal cell carcinoma
Published in Journal of medical virology (01-06-2013)“…The objective of the present study was to investigate the potential association between the presence of BK virus (BKV) DNA and mRNA and renal cell carcinoma…”
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Treatment with TREK1 and TRPC3/6 ion channel inhibitors upregulates microRNA expression in a mouse model of chronic mild stress
Published in Neuroscience letters (24-08-2017)“…•It is the first study to show that ion channel inhibitors known as norgestimate and anadamide have antidepressive effects.•The TRPC3/TRPC6 calcium channel…”
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The increased expression of Piezo1 and Piezo2 ion channels in human and mouse bladder carcinoma
Published in Advances in clinical and experimental medicine : official organ Wroclaw Medical University (01-08-2018)“…Piezo1/2, a mechanically activated ion channel, is believed to play an important role in bladder carcinogenesis process. Piezo1/2 expression has not been…”
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