Search Results - "Eswar, R."

Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite by Cerutti, Gabriele, Guo, Yicheng, Zhou, Tongqing, Gorman, Jason, Lee, Myungjin, Rapp, Micah, Reddem, Eswar R., Yu, Jian, Bahna, Fabiana, Bimela, Jude, Huang, Yaoxing, Katsamba, Phinikoula S., Liu, Lihong, Nair, Manoj S., Rawi, Reda, Olia, Adam S., Wang, Pengfei, Zhang, Baoshan, Chuang, Gwo-Yu, Ho, David D., Sheng, Zizhang, Kwong, Peter D., Shapiro, Lawrence

“…Numerous antibodies that neutralize SARS-CoV-2 have been identified, and these generally target either the receptor-binding domain (RBD) or the N-terminal…”
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Exploring the use of satellite observations of soil moisture, solar-induced chlorophyll fluorescence and vegetation optical depth to monitor droughts across India by Likith, M, Harod, Rahul, Eswar, R

“…The aim of this study is to explore the potential of remotely sensed soil moisture (SM), solar-induced chlorophyll fluorescence (SIF) and vegetation optical…”
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Highly efficient Cas9-mediated transcriptional programming by Chavez, Alejandro, Scheiman, Jonathan, Vora, Suhani, Pruitt, Benjamin W, Tuttle, Marcelle, P R Iyer, Eswar, Lin, Shuailiang, Kiani, Samira, Guzman, Christopher D, Wiegand, Daniel J, Ter-Ovanesyan, Dmitry, Braff, Jonathan L, Davidsohn, Noah, Housden, Benjamin E, Perrimon, Norbert, Weiss, Ron, Aach, John, Collins, James J, Church, George M

“…The fusion of three transcriptional activation domains to a nuclease-deficient Cas9 achieves robust induction of gene expression and can induce differentiation…”
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Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies by Cerutti, Gabriele, Rapp, Micah, Guo, Yicheng, Bahna, Fabiana, Bimela, Jude, Reddem, Eswar R., Yu, Jian, Wang, Pengfei, Liu, Lihong, Huang, Yaoxing, Ho, David D., Kwong, Peter D., Sheng, Zizhang, Shapiro, Lawrence

“…Emerging SARS-CoV-2 strains, B.1.1.7 and B.1.351, from the UK and South Africa, respectively, show decreased neutralization by monoclonal antibodies and…”
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Disaggregation of LST over India: comparative analysis of different vegetation indices by Eswar, R., Sekhar, M., Bhattacharya, B. K.

“…The non-availability of high-spatial-resolution thermal data from satellites on a consistent basis led to the development of different models for sharpening…”
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Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain by Cerutti, Gabriele, Guo, Yicheng, Wang, Pengfei, Nair, Manoj S., Wang, Maple, Huang, Yaoxing, Yu, Jian, Liu, Lihong, Katsamba, Phinikoula S., Bahna, Fabiana, Reddem, Eswar R., Kwong, Peter D., Ho, David D., Sheng, Zizhang, Shapiro, Lawrence

“…Antibodies that potently neutralize SARS-CoV-2 target mainly the receptor-binding domain or the N-terminal domain (NTD). Over a dozen potently neutralizing…”
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Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class by Rapp, Micah, Guo, Yicheng, Reddem, Eswar R., Yu, Jian, Liu, Lihong, Wang, Pengfei, Cerutti, Gabriele, Katsamba, Phinikoula, Bimela, Jude S., Bahna, Fabiana A., Mannepalli, Seetha M., Zhang, Baoshan, Kwong, Peter D., Huang, Yaoxing, Ho, David D., Shapiro, Lawrence, Sheng, Zizhang

“…Antibodies with heavy chains that derive from the VH1-2 gene constitute some of the most potent severe acute respiratory syndrome coronavirus 2…”
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The Utility of Simpler Spatial Disaggregation Models for Retrieving Land Surface Temperature at High Spatiotemporal Resolutions by Sara, Kukku, Eswar, R., Bhattacharya, B. K.

“…The thermal infrared (TIR) sensors aboard geostationary satellites provide multi-temporal land surface temperature (LST) observations for characterizing the…”
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Decadal gross level assessment of green and blue consumptive water use over Indian agro-ecosystems by Choudhury, Indrani, Bhattacharya, B.K., Eswar, R., Sekhar, M.

“…Assessment of consumptive water use (CWU) and water productivity at the regional scale is important to diagnose vulnerable zones to improve water use…”
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P(VDF-TrFE-CFE) polymer based electrocaloric device design for battery cooling by Rabadiya, Ridhamkumar, Sai Eswar, R. S., Ch, Surya Narayana, Saurabh, Nishchay, Patel, Satyanarayan

“…Electrocaloric (EC) cooling has the potential to be an alternative to traditional cooling methods. The polyvinylidene fluoride-trifluoro…”
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Validation and bias correction of incoming solar radiation from two reanalysis products over India by Jain, Anushriya, Eswar, R, Bhattacharya, B K

“…Reanalysis datasets are valuable sources of long-term meteorological information. Among the many variables, surface solar radiation ( R sd ) is one of the…”
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First crystal structures of 1-deoxy-d-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization by Gierse, Robin M., Oerlemans, Rick, Reddem, Eswar R., Gawriljuk, Victor O., Alhayek, Alaa, Baitinger, Dominik, Jakobi, Harald, Laber, Bernd, Lange, Gudrun, Hirsch, Anna K. H., Groves, Matthew R.

“…The development of drug resistance by Mycobacterium tuberculosis and other pathogenic bacteria emphasizes the need for new antibiotics. Unlike animals, most…”
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Modeling Evapotranspiration at Larger Temporal Scales: Effects of Temporal Aggregation and Data Gaps by Athira, K. V., Eswar, R., Boulet, Gilles, Nigam, Rahul, Bhattacharya, Bimal K.

“…Evapotranspiration (ET) at weekly and monthly time scales is often needed for various applications. When using remote sensing (RS)-based models, this can be…”
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Explaining Operational Instability of Amine Transaminases: Substrate-Induced Inactivation Mechanism and Influence of Quaternary Structure on Enzyme–Cofactor Intermediate Stability by Börner, Tim, Rämisch, Sebastian, Reddem, Eswar R, Bartsch, Sebastian, Vogel, Andreas, Thunnissen, Andy-Mark W. H, Adlercreutz, Patrick, Grey, Carl

“…The insufficient operational stability of amine transaminases (ATA) constitutes a limiting factor for high productivity in chiral amine synthesis. In this…”
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The TRP Channels Pkd2, NompC, and Trpm Act in Cold-Sensing Neurons to Mediate Unique Aversive Behaviors to Noxious Cold in Drosophila by Turner, Heather N., Armengol, Kevin, Patel, Atit A., Himmel, Nathaniel J., Sullivan, Luis, Iyer, Srividya Chandramouli, Bhattacharya, Surajit, Iyer, Eswar Prasad R., Landry, Christian, Galko, Michael J., Cox, Daniel N.

“…The basic mechanisms underlying noxious cold perception are not well understood. We developed Drosophila assays for noxious cold responses. Larvae respond to…”
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Identification of a 1-deoxy-D-xylulose-5-phosphate synthase (DXS) mutant with improved crystallographic properties by Gierse, Robin M., Reddem, Eswar R., Alhayek, Alaa, Baitinger, Dominik, Hamid, Zhoor, Jakobi, Harald, Laber, Bernd, Lange, Gudrun, Hirsch, Anna K.H., Groves, Matthew R.

“…In this report, we describe a truncated Deinococcus radiodurans 1-deoxy-D-xylulose-5-phosphate synthase (DXS) protein that retains enzymatic activity, while…”
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The Zinc-BED Transcription Factor Bedwarfed Promotes Proportional Dendritic Growth and Branching through Transcriptional and Translational Regulation in Drosophila by Bhattacharjee, Shatabdi, Iyer, Eswar Prasad R, Iyer, Srividya Chandramouli, Nanda, Sumit, Rubaharan, Myurajan, Ascoli, Giorgio A, Cox, Daniel N

“…Dendrites are the primary points of sensory or synaptic input to a neuron and play an essential role in synaptic integration and neural function. Despite the…”
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Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking by Liu, Lihong, Casner, Ryan G., Guo, Yicheng, Wang, Qian, Iketani, Sho, Chan, Jasper Fuk-Woo, Yu, Jian, Dadonaite, Bernadeta, Nair, Manoj S., Mohri, Hiroshi, Reddem, Eswar R., Yuan, Shuofeng, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Yuen, Kwok-Yung, Sheng, Zizhang, Huang, Yaoxing, Bloom, Jesse D., Shapiro, Lawrence, Ho, David D.

“…SARS-CoV-2 continues to evolve, with many variants evading clinically authorized antibodies. To isolate monoclonal antibodies (mAbs) with broadly neutralizing…”
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An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses by Liu, Lihong, Iketani, Sho, Guo, Yicheng, Reddem, Eswar R, Casner, Ryan G, Nair, Manoj S, Yu, Jian, Chan, Jasper F-W, Wang, Maple, Cerutti, Gabriele, Li, Zhiteng, Morano, Nicholas C, Castagna, Candace D, Corredor, Laura, Chu, Hin, Yuan, Shuofeng, Poon, Vincent Kwok-Man, Chan, Chris Chun-Sing, Chen, Zhiwei, Luo, Yang, Cunningham, Marcus, Chavez, Alejandro, Yin, Michael T, Perlin, David S, Tsuji, Moriya, Yuen, Kwok-Yung, Kwong, Peter D, Sheng, Zizhang, Huang, Yaoxing, Shapiro, Lawrence, Ho, David D

“…The devastation caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made clear the importance of pandemic preparedness. To address…”
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SMOS optical thickness changes in response to the growth and development of crops, crop management, and weather by Hornbuckle, Brian K., Patton, Jason C., VanLoocke, Andy, Suyker, Andrew E., Roby, Matthew C., Walker, Victoria A., Iyer, Eswar R., Herzmann, Daryl E., Endacott, Erik A.

“…The Soil Moisture and Ocean Salinity (SMOS) remote sensing satellite was launched by the European Space Agency in 2009. The L-band brightness temperature…”
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