Search Results - "Estrada‐Parra, Sergio"
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Anti‐inflammatory effect of omega unsaturated fatty acids and dialysable leucocyte extracts on collagen‐induced arthritis in DBA/1 mice
Published in International journal of experimental pathology (01-02-2020)“…Summary Rheumatoid arthritis is a disabling autoimmune disease with a high global prevalence. Treatment with disease‐modifying anti‐arthritic drugs (DIMARDs)…”
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Severe COVID‐19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin
Published in Journal of leukocyte biology (01-09-2021)“…The immune response plays a critical role in the pathophysiology of SARS‐CoV‐2 infection ranging from protection to tissue damage and all occur in the…”
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The Role of Bacterial Extracellular Vesicles in the Immune Response to Pathogens, and Therapeutic Opportunities
Published in International journal of molecular sciences (01-06-2024)“…Pathogenic bacteria have several mechanisms to evade the host's immune response and achieve an efficient infection. Bacterial extracellular vesicles (EVs) are…”
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Extracellular Vesicles Released from Mycobacterium tuberculosis -Infected Neutrophils Promote Macrophage Autophagy and Decrease Intracellular Mycobacterial Survival
Published in Frontiers in immunology (19-02-2018)“…Tuberculosis is an infectious disease caused by (Mtb). In the lungs, macrophages and neutrophils are the first immune cells that have contact with the…”
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Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Published in Journal of immunology research (01-01-2019)“…Valproic acid (VPA) is widely recognized for its use in the control of epilepsy and other neurological disorders in the past 50 years. Recent evidence has…”
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Valproic acid restricts mast cell activation by Listeria monocytogenes
Published in Scientific reports (20-09-2022)“…Mast cells (MC) play a central role in the early containment of bacterial infections, such as that caused by Listeria monocytogenes (L.m). The mechanisms of MC…”
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The histone deacetylase inhibitor valproic acid attenuates phospholipase Cγ2 and IgE‐mediated mast cell activation
Published in Journal of leukocyte biology (01-09-2020)“…Mast cell activation through the high‐affinity IgE receptor (FcεRI) plays a central role in allergic reactions. FcεRI‐mediated activation triggers multiple…”
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Elevated levels of enteric IgA in an unimmunised mouse model of Hyper IgM syndrome derived from gut-associated secondary lymph organs even in the absence of germinal centres
Published in Frontiers in cellular and infection microbiology (29-06-2023)“…Patients with Human Hyper IgM syndromes (HIGM) developed pulmonary and gastrointestinal infections since infancy and most patients have mutations in the CD40…”
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Recognition of Candida albicans by Dectin-1 induces mast cell activation
Published in Immunobiology (1979) (01-09-2015)“…Abstract Mast cells are crucial elements of the innate immune response. They reside in tissues that are commonly exposed to the external environment, such as…”
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TLR2 Regulates Mast Cell IL-6 and IL-13 Production During Listeria monocytogenes Infection
Published in Frontiers in immunology (14-06-2021)“…(L.m) is efficiently controlled by several cells of the innate immunity, including the Mast Cell (MC). MC is activated by L.m inducing its degranulation,…”
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Validation of a Cell Proliferation Assay to Assess the Potency of a Dialyzable Leukocyte Extract Intended for Batch Release
Published in Molecules (Basel, Switzerland) (20-09-2019)“…Transferon is a blood product with immunomodulatory properties constituted by a complex mixture of peptides obtained from a human dialyzable leukocyte extract…”
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Mycobacterium tuberculosis Catalase Inhibits the Formation of Mast Cell Extracellular Traps
Published in Frontiers in immunology (28-05-2018)“…Tuberculosis is one of the leading causes of human morbidity and mortality. (Mtb) employs different strategies to evade and counterattack immune responses…”
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CD80 Expression Correlates with IL-6 Production in THP-1-Like Macrophages Costimulated with LPS and Dialyzable Leukocyte Extract (Transferon®)
Published in Journal of immunology research (01-01-2019)“…Transferon® is a complex drug based on a mixture of low molecular weight peptides. This biotherapeutic is employed as a coadjuvant in clinical trials of…”
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Effect of Selective Serotonin Reuptake Inhibitors and Immunomodulator on Cytokines Levels: An Alternative Therapy for Patients with Major Depressive Disorder
Published in Clinical & developmental immunology (01-01-2013)“…Major depressive disorder (MDD) is a psychiatric illness that presents as a deficit of serotonergic neurotransmission in the central nervous system. MDD…”
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Early Differentiation of Human CD11c+NK Cells with γδ T Cell Activation Properties Is Promoted by Dialyzable Leukocyte Extracts
Published in Journal of immunology research (01-01-2016)“…Reconstitution of the hematopoietic system during immune responses and immunological and neoplastic diseases or upon transplantation depends on the emergent…”
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Increased Pro-inflammatory Cytokine Production After Lipopolysaccharide Stimulation in Patients with X-linked Agammaglobulinemia
Published in Journal of clinical immunology (01-10-2012)“…Purpose To evaluate the lipopolysaccharide (LPS)-induced pro-inflammatory cytokine response by peripheral blood mononuclear cells (PBMCs) from XLA patients…”
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HLA Alleles are Genetic Markers for Susceptibility and Resistance towards Leprosy in a Mexican Mestizo Population
Published in Annals of human genetics (01-01-2017)“…Summary Despite the use of multidrug therapy, leprosy remains endemic in some countries. The association of several human leucocyte antigen (HLA) alleles and…”
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Activated endothelial cells limit inflammatory response, but increase chemoattractant potential and bacterial clearance by human monocytes
Published in Cell biology international (01-06-2015)“…Inflammation is the normal immune response of vascularized tissues to damage and bacterial products, for which leukocyte transendothelial migration (TEM) is…”
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Herpes Murine Model as a Biological Assay to Test Dialyzable Leukocyte Extracts Activity
Published in Journal of immunology research (01-01-2015)“…Human dialyzable leukocyte extracts (DLEs) are heterogeneous mixtures of low-molecular-weight peptides that are released on disruption of peripheral blood…”
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Mycobacterium tuberculosis lipids regulate cytokines, TLR-2/4 and MHC class II expression in human macrophages
Published in Tuberculosis (Edinburgh, Scotland) (01-05-2008)“…Summary The interaction of macrophages with Mycobacterium tuberculosis through Toll-like receptors is critical in defining the cytokine profile that may or may…”
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