Search Results - "Estrada‐Gutierrez, Guadalupe"
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Battle of epigenetic proportions: comparing Illumina's EPIC methylation microarrays and TruSeq targeted bisulfite sequencing
Published in Epigenetics (01-02-2020)“…DNA methylation microarrays have been the platform of choice for epigenome-wide association studies in epidemiology, but declining costs have rendered targeted…”
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Earlier detection of gestational diabetes impacts on medication requirements, neonatal and maternal outcomes
Published in Diabetes, obesity & metabolism (01-08-2024)“…Aim Gestational diabetes (GD) is a global health concern with significant implications for maternal and neonatal outcomes. This study investigates the…”
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Syncytiotrophoblast of Placentae from Women with Zika Virus Infection Has Altered Tight Junction Protein Expression and Increased Paracellular Permeability
Published in Cells (Basel, Switzerland) (29-09-2019)“…The cytotrophoblast of human placenta transitions into an outer multinucleated syncytiotrophoblast (STB) layer that covers chorionic villi which are in contact…”
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Neonatal Antibiotic Treatment Can Affect Stool Pattern and Oral Tolerance in Preterm Infants
Published in Life (Basel, Switzerland) (13-07-2022)“…Preterm neonates are at high risk of infectious and inflammatory diseases which require antibiotic treatment. Antibiotics influence neonatal gut microbiome…”
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Progesterone Elicits an Inhibitory Effect upon LPS-Induced Innate Immune Response in Pre-Labor Human Amniotic Epithelium
Published in American journal of reproductive immunology (1989) (01-01-2014)“…Problem Infection of human fetal membranes elicits secretion of pro‐inflammatory modulators through its innate immune capacities. We investigated the effect of…”
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Early-Life Dietary Cadmium Exposure and Kidney Function in 9-Year-Old Children from the PROGRESS Cohort
Published in Toxics (Basel) (07-10-2020)“…Cadmium (Cd) is a toxic metal associated with adverse health effects, including kidney injury or disease. The aims of this study were to estimate dietary Cd…”
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Single-cell analysis reveals transcriptomic and epigenomic impacts on the maternal–fetal interface following SARS-CoV-2 infection
Published in Nature cell biology (01-07-2023)“…During pregnancy the maternal–fetal interface plays vital roles in fetal development. Its disruption is frequently found in pregnancy complications. Recent…”
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New Insights into the Role of Matrix Metalloproteinases in Preeclampsia
Published in International journal of molecular sciences (20-07-2017)“…Preeclampsia is a severe pregnancy complication globally, characterized by poor placentation triggering vascular dysfunction. Matrix metalloproteinases (MMPs)…”
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Excessive Pregestational Weight and Maternal Obstetric Complications: The Role of Adipokines
Published in International journal of molecular sciences (01-10-2023)“…There is a high frequency of overweight and obesity in women of reproductive age. Women who start pregnancy with overweight or obesity have an increased risk…”
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Placental Microarray Profiling Reveals Common mRNA and lncRNA Expression Patterns in Preeclampsia and Intrauterine Growth Restriction
Published in International journal of molecular sciences (20-05-2020)“…Preeclampsia (PE) and Intrauterine Growth Restriction (IUGR) are major contributors to perinatal morbidity and mortality. These pregnancy disorders are…”
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A Narrative Review on the Pathophysiology of Preeclampsia
Published in International journal of molecular sciences (01-07-2024)“…Preeclampsia (PE) is a multifactorial pregnancy disorder characterized by hypertension and proteinuria, posing significant risks to both maternal and fetal…”
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Prenatal and early childhood critical windows for the association of nephrotoxic metal and metalloid mixtures with kidney function
Published in Environment international (01-08-2022)“…[Display omitted] As renal development and maturation processes begin in utero and continue through early childhood, sensitive developmental periods arise…”
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Regulation of MMP-2 by IL-8 in Vascular Endothelial Cells: Probable Mechanism for Endothelial Dysfunction in Women with Preeclampsia
Published in International journal of molecular sciences (21-12-2023)“…Endothelial dysfunction (ED) in preeclampsia (PE) results from the convergence of oxidative stress, inflammation, and alterations in extracellular matrix…”
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Prenatal manganese and cord blood mitochondrial DNA copy number: Effect modification by maternal anemic status
Published in Environment international (01-05-2019)“…Manganese (Mn) is an essential nutrient but also a toxicant at high exposures, when it can induce oxidative stress (OS). Mn uptake is inversely correlated with…”
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S100B actions on glial and neuronal cells in the developing brain: an overview
Published in Frontiers in neuroscience (04-07-2024)“…The S100B is a member of the S100 family of "E" helix-loop- "F" helix structure (EF) hand calcium-binding proteins expressed in diverse glial, selected…”
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Influential Serum Kinases (Non-sFlt-1) and Phosphatases in Preeclampsia—Systemic Review and Metanalysis
Published in International journal of molecular sciences (16-08-2023)“…The early identification of women with an increased risk of preeclampsia (PE) is desirable, but apart from soluble fms-like tyrosine kinase-1 (sFlt-1), few…”
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A Novel Predictive Machine Learning Model Integrating Cytokines in Cervical-Vaginal Mucus Increases the Prediction Rate for Preterm Birth
Published in International journal of molecular sciences (01-09-2023)“…Preterm birth (PB) is a leading cause of perinatal morbidity and mortality. PB prediction is performed by measuring cervical length, with a detection rate of…”
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Prenatal blood lead levels and reduced preadolescent glomerular filtration rate: Modification by body mass index
Published in Environment international (01-09-2021)“…•Overall, we observed null associations between perinatal lead exposure and kidney function.•Perinatal BLLs were associated with reduced preadolescent eGFR…”
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Nutrients, Mitochondrial Function, and Perinatal Health
Published in Nutrients (21-07-2020)“…Mitochondria are active independent organelles that not only meet the cellular energy requirement but also regulate central cellular activities. Mitochondria…”
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Altered cord blood mitochondrial DNA content and pregnancy lead exposure in the PROGRESS cohort
Published in Environment international (01-04-2019)“…Lead (Pb) crosses the placenta and can cause oxidative stress, reduced fetal growth and neurological problems. The principal source of oxidative stress in…”
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