Search Results - "Estrada, Paola"
-
1
Characterization of the macrocyclase involved in the biosynthesis of RiPP cyclic peptides in plants
Published in Proceedings of the National Academy of Sciences - PNAS (20-06-2017)“…Enzymes that can catalyze the macrocyclization of linear peptide substrates have long been sought for the production of libraries of structurally diverse…”
Get full text
Journal Article -
2
A Single Amino Acid Switch Alters the Isoprene Donor Specificity in Ribosomally Synthesized and Post-Translationally Modified Peptide Prenyltransferases
Published in Journal of the American Chemical Society (05-07-2018)“…Mutation at a single amino acid alters the isoprene donor specificity of prenyltransferases involved in the modification of ribosomally synthesized and…”
Get full text
Journal Article -
3
Characterization of a Dehydratase and Methyltransferase in the Biosynthesis of Ribosomally Synthesized and Post‐translationally Modified Peptides in Lachnospiraceae
Published in Chembiochem : a European journal of chemical biology (15-01-2020)“…As a result of the exponential increase in genomic data, discovery of novel ribosomally synthesized and post‐translationally modified peptide natural products…”
Get full text
Journal Article -
4
Biosynthesis of the RiPP trojan horse nucleotide antibiotic microcin C is directed by the N -formyl of the peptide precursor
Published in Chemical science (Cambridge) (28-02-2019)“…Microcin C7 (McC) is a peptide antibiotic modified by a linkage of the terminal isoAsn amide to AMP a phosphoramidate bond. Post-translational modification on…”
Get full text
Journal Article -
5
Assessment of the biodegradation of doxycycline by biostimulation with addition of glucose, phenol or/and copper
Published in Ecocycles (01-11-2020)“…Doxycycline, an antibiotic, is largely used in human and veterinary medicine. The conventional treatment with activated sludge is not very efficient. Laccase…”
Get full text
Journal Article -
6
The pimeloyl-CoA synthetase BioW defines a new fold for adenylate-forming enzymes
Published in Nature chemical biology (01-06-2017)“…Structural analysis of pimeloyl-CoA synthetase (BioW) provides insight into how the enzyme ensures proper substrate positioning and how a key residue ensures…”
Get full text
Journal Article -
7
A Single Amino Acid Switch Alters the Isoprene Donor Specificity in RiPP Prenyltransferases
Published in Journal of the American Chemical Society (26-06-2018)“…Mutation at a single amino acid alters the isoprene donor specificity of prenyltransferases involved in the modification of ribosomally synthesized and…”
Get full text
Journal Article -
8
-
9
Biosynthesis of the RiPP trojan horse nucleotide antibiotic microcin C is directed by the N-formyl of the peptide precursorElectronic supplementary information (ESI) available: Experimental procedures, X-ray crystallographic data, and FP biding curves. See DOI: 10.1039/c8sc03173h
Published 20-02-2019“…Microcin C7 (McC) is a peptide antibiotic modified by a linkage of the terminal isoAsn amide to AMP via a phosphoramidate bond. Post-translational modification…”
Get full text
Journal Article -
10
Biosynthesis of the RiPP trojan horse nucleotide antibiotic microcin C is directed by the N-formyl of the peptide precursor
Published in Chemical science (Cambridge) (26-12-2018)“…Microcin C7 (McC) is a peptide antibiotic modified by a linkage of the terminal isoAsn amide to AMP via a phosphoramidate bond. Post-translational modification…”
Get full text
Journal Article -
11
Biosynthesis of the RiPP trojan horse nucleotide antibiotic microcin C is directed by the N-formyl of the peptide precursor† †Electronic supplementary information (ESI) available: Experimental procedures, X-ray crystallographic data, and FP biding curves. See DOI: 10.1039/c8sc03173h
Published in Chemical science (Cambridge) (26-12-2018)“…The N -formyl moiety of the peptide precursor directs the biosynthesis of the RiPP trojan horse nucleotide antibiotic McC. Microcin C7 (McC) is a peptide…”
Get full text
Journal Article -
12
-
13
Clinical–epidemiological characterization of cervical cancer in a middle-income country
Published in Journal of clinical oncology (01-06-2024)“…e17514 Background: Despite significant advances in prevention and treatment, cervical cancer remains a global public health threat, claiming the lives of…”
Get full text
Journal Article -
14
-
15
O Brasil, a Venezuela e os movimentos sociais no contexto da América Latina e do Império
Published in Germinal : marxismo e educação em debate (16-12-2017)“…Na seção Entrevista sob o título O Brasil, a Venezuela e os movimentos sociais no contexto da América Latina e do império, reunimos três entrevistas. Uma,…”
Get full text
Journal Article