Search Results - "Estey, Carmen"
-
1
Electron Transport Chain-dependent and -independent Mechanisms of Mitochondrial H2O2 Emission during Long-chain Fatty Acid Oxidation
Published in The Journal of biological chemistry (19-02-2010)“…Oxidative stress in skeletal muscle is a hallmark of various pathophysiologic states that also feature increased reliance on long-chain fatty acid (LCFA)…”
Get full text
Journal Article -
2
SirT1 regulates energy metabolism and response to caloric restriction in mice
Published in PloS one (12-03-2008)“…The yeast sir2 gene and its orthologues in Drosophila and C. elegans have well-established roles in lifespan determination and response to caloric restriction…”
Get full text
Journal Article -
3
Essential Role for Uncoupling Protein-3 in Mitochondrial Adaptation to Fasting but Not in Fatty Acid Oxidation or Fatty Acid Anion Export
Published in The Journal of biological chemistry (12-09-2008)“…Uncoupling protein-3 (UCP3) is a mitochondrial inner membrane protein expressed most abundantly in skeletal muscle and to a lesser extent in heart and brown…”
Get full text
Journal Article -
4
Regulation of Ischemic Neuronal Death by E2F4-p130 Protein Complexes
Published in The Journal of biological chemistry (27-06-2014)“…Inappropriate activation of cell cycle proteins, in particular cyclin D/Cdk4, is implicated in neuronal death induced by various pathologic stresses, including…”
Get full text
Journal Article -
5
Intrinsic aerobic capacity correlates with greater inherent mitochondrial oxidative and H2O2 emission capacities without major shifts in myosin heavy chain isoform
Published in Journal of applied physiology (1985) (01-11-2012)“…Exercise capacity and performance strongly associate with metabolic and biophysical characteristics of skeletal muscle, factors that also relate to overall…”
Get full text
Journal Article -
6
Calorie restriction in mice overexpressing UCP3: Evidence that prior mitochondrial uncoupling alters response
Published in Experimental gerontology (01-05-2012)“…Calorie restriction (CR) without malnutrition is the only intervention to consistently increase lifespan in all species tested, and lower age-related…”
Get full text
Journal Article -
7
Intrinsic aerobic capacity correlates with greater inherent mitochondrial oxidative and H^sub 2^O^sub 2^ emission capacities without major shifts in myosin heavy chain isoform
Published in Journal of applied physiology (1985) (15-11-2012)“…Exercise capacity and performance strongly associate with metabolic and biophysical characteristics of skeletal muscle, factors that also relate to overall…”
Get full text
Journal Article -
8
Intrinsic aerobic capacity correlates with greater inherent mitochondrial oxidative and H 2 O 2 emission capacities without major shifts in myosin heavy chain isoform
Published in Journal of applied physiology (1985) (15-11-2012)“…Exercise capacity and performance strongly associate with metabolic and biophysical characteristics of skeletal muscle, factors that also relate to overall…”
Get full text
Journal Article -
9
Absence of uncoupling protein-3 leads to greater activation of an adenine nucleotide translocase-mediated proton conductance in skeletal muscle mitochondria from calorie restricted mice
Published in Biochimica et biophysica acta (01-08-2010)“…Calorie restriction (CR), without malnutrition, consistently increases lifespan in all species tested, and reduces age-associated pathologies in mammals…”
Get full text
Journal Article -
10
Mitochondrial uncoupling and remodeling during caloric restriction: Implications for oxidative stress and aging
Published in The FASEB journal (01-04-2009)“…Abstract only Caloric restriction (CR) mitigates aging; however, mechanisms are poorly understood. The 'uncoupling to survive' theory suggests that…”
Get full text
Journal Article -
11