Search Results - "Esteve‐Arenys, Anna"
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Dual targeting of MCL1 and NOXA as effective strategy for treatment of mantle cell lymphoma
Published in British journal of haematology (01-05-2017)“…Summary Imbalances in the composition of BCL2 family proteins contribute to tumourigenesis and therapy resistance of mantle cell lymphoma (MCL), making these…”
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Cytoplasmic cyclin D1 controls the migration and invasiveness of mantle lymphoma cells
Published in Scientific reports (24-10-2017)“…Mantle cell lymphoma (MCL) is a hematologic neoplasm characterised by the t(11;14)(q13;q32) translocation leading to aberrant cyclin D1 expression. The cell…”
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Pharmacological modulation of CXCR4 cooperates with BET bromodomain inhibition in diffuse large B-cell lymphoma
Published in Haematologica (Roma) (01-04-2019)“…Constitutive activation of the chemokine receptor CXCR4 has been associated with tumor progression, invasion, and chemotherapy resistance in different cancer…”
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BFL-1 expression determines the efficacy of venetoclax in MYC+/BCL2+ double hit lymphoma
Published in Oncoscience (29-04-2018)Get full text
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A mouse model of disseminated mantle cell lymphoma highlights a lack of activity of estrogen receptor β agonists toward tumor burden
Published in Leukemia & lymphoma (03-07-2018)Get full text
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ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1
Published in Gut (01-04-2017)“…Understand the role of ZEB1 in the tumour initiation and progression beyond inducing an epithelial-to-mesenchymal transition. Expression of the transcription…”
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The BET Inhibitor GS-626510 Converges with Idelalisib through the Inhibition of Tumor-Macrophage Crosstalk and Cytokine Production in Diffuse Large B-Cell Lymphoma
Published in Blood (08-12-2017)“…Background: The recent observation that components of the tumor microenvironment, including M2 tumor-associated macrophages, may define a subgroup of diffuse…”
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Abstract 2161: Pharmacological downregulation of BFL-1 by the BET bromodomain inhibitor CPI203 overcomes ABT-199 resistance in MYC+/BCL2+ double hit lymphoma
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Double-hit lymphoma (DHL) is a rare subtype of B-cell lymphoma characterized by MYC and either BCL2 or BCL6 chromosomal rearrangements. DHL cases may…”
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Binge ethanol drinking during adolescence modifies cocaine responses in mice
Published in Journal of psychopharmacology (Oxford) (01-01-2017)“…Binge ethanol drinking is an emerging pattern of excessive consumption among adolescents and young adults. Repeated ethanol intoxication has negative…”
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Abstract 2169: Pharmacological modulation of CXCL12-CXCR4 intracellular trafficking potentiates the in vitro and in vivo activity of the BET bromodomain inhibitor CPI203 in diffuse large B-cell lymphoma
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Constitutive activation of CXCR4, a chemokine receptor commonly overexpressed in cancer, is associated with tumor progression, invasion, and…”
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Pharmacological modulation of CXCR4 cooperates with BET bromodomain inhibition in diffuse large B-cell lymphoma
Published in Haematologica (Roma) (01-04-2019)“…Constitutive activation of the chemokine receptor CXCR4 has been associated with tumor progression, invasion, and chemotherapy resistance in different cancer…”
Get full text
Journal Article