Search Results - "Esterhai, John L"

Programmed biomolecule delivery to enable and direct cell migration for connective tissue repair by Qu, Feini, Holloway, Julianne L., Esterhai, John L., Burdick, Jason A., Mauck, Robert L.

“…Dense connective tissue injuries have limited repair, due to the paucity of cells at the wound site. We hypothesize that decreasing the density of the local…”
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Sacrificial nanofibrous composites provide instruction without impediment and enable functional tissue formation by Baker, Brendon M, Shah, Roshan P, Silverstein, Amy M, Esterhai, John L, Burdick, Jason A, Mauck, Robert L

“…The fibrous tissues prevalent throughout the body possess an ordered structure that underlies their refined and robust mechanical properties. Engineered…”
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Biomaterial-mediated delivery of degradative enzymes to improve meniscus integration and repair by Qu, Feini, Lin, Jung-Ming G., Esterhai, John L., Fisher, Matthew B., Mauck, Robert L.

“…Endogenous repair of fibrous connective tissues is limited, and there exist few successful strategies to improve healing after injury. As such, new methods…”
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Use of Medical Comorbidities to Predict Complications After Hip Fracture Surgery in the Elderly by Donegan, Derek J, Gay, A Nicolas, Baldwin, Keith, Morales, Edwin E, Esterhai, John L, Mehta, Samir

“…BACKGROUND:Comorbidities before and complications following hip fracture surgery can impact the return of function. We hypothesized that the American Society…”
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Open Tibial Shaft Fractures: I. Evaluation and Initial Wound Management by Melvin, J Stuart, Dombroski, Derek G, Torbert, Jesse T, Kovach, Stephen J, Esterhai, John L, Mehta, Samir

“…Open fractures of the tibial diaphysis are often associated with severe bone and soft-tissue injury. Contamination of the fracture site and devitalization of…”
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Prospective Intraoperative Syndesmotic Evaluation During Ankle Fracture Fixation: Stress External Rotation Versus Lateral Fibular Stress by Matuszewski, Paul E, Dombroski, Derek, Lawrence, J. Todd R, Esterhai, John L, Mehta, Samir

“…OBJECTIVES:We hypothesized that the method of stress external rotation more accurately reproduces the mechanism of injury, and therefore this diagnostic method…”
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Open Tibial Shaft Fractures: II. Definitive Management and Limb Salvage by Melvin, J Stuart, Dombroski, Derek G, Torbert, Jesse T, Kovach, Stephen J, Esterhai, John L, Mehta, Samir

“…Definitive treatment of open fractures of the tibial diaphysis is challenging. The high-energy nature of these fractures, as well as the contamination of the…”
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Antibiotic Treatment and Timing of Reimplantation by Restrepo, Camilo, MD, Schmitt, Steven, MD (US), Backstein, David, MD (International), Alexander, Bryan T., PharmD, Babic, Maja, MD, Brause, Barry D., MD, Esterhai, John L., MD, Good, Robert P., MD, Jørgensen, Peter H., MD, Lee, Paul, MB, BCh, FRCS, Marculescu, Camelia, MD, Mella, Claudio, MD, Perka, Carsten, MD, Pour, Aidin Eslam, MD, Rubash, Harry E., MD, Saito, Tomoyuki, MD, Suarez, Rolando, MD, Townsend, Robert, MD, Tözün, I. Remzi, MD, Van den Bekerom, Michel P.J., MD

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Papers Presented at the 2009 Meeting of the Musculoskeletal Infection Society: Editorial Comment by Esterhai, John L., Wongworawat, Montri D.

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Engineering meniscus structure and function via multi-layered mesenchymal stem cell-seeded nanofibrous scaffolds by Fisher, Matthew B, Henning, Elizabeth A, Söegaard, Nicole, Bostrom, Marc, Esterhai, John L, Mauck, Robert L

“…Abstract Despite advances in tissue engineering for the knee meniscus, it remains a challenge to match the complex macroscopic and microscopic structural…”
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Organized nanofibrous scaffolds that mimic the macroscopic and microscopic architecture of the knee meniscus by Fisher, Matthew B., Henning, Elizabeth A., Söegaard, Nicole, Esterhai, John L., Mauck, Robert L.

“…The menisci are crescent-shaped fibrocartilaginous tissues whose structural organization consists of dense collagen bundles that are locally aligned but show a…”
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Repair of dense connective tissues via biomaterial-mediated matrix reprogramming of the wound interface by Qu, Feini, Pintauro, Michael P, Haughan, Joanne E, Henning, Elizabeth A, Esterhai, John L, Schaer, Thomas P, Mauck, Robert L, Fisher, Matthew B

“…Abstract Repair of dense connective tissues in adults is limited by their intrinsic hypocellularity and is exacerbated by a dense extracellular matrix (ECM)…”
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Maturation State and Matrix Microstructure Regulate Interstitial Cell Migration in Dense Connective Tissues by Qu, Feini, Li, Qing, Wang, Xiao, Cao, Xuan, Zgonis, Miltiadis H., Esterhai, John L., Shenoy, Vivek B., Han, Lin, Mauck, Robert L.

“…Few regenerative approaches exist for the treatment of injuries to adult dense connective tissues. Compared to fetal tissues, adult connective tissues are…”
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Effects of Immobilization on Plantar-Flexion Torque, Fatigue Resistance, and Functional Ability Following an Ankle Fracture by Michael A Shaffer, Enyi Okereke, John L Esterhai, Jr, Mark A Elliott, Glenn A Walter, Steven H Yim, Krista Vandenborne

“…The goal of this investigation was to study the recovery of ankle plantar-flexor peak torque, fatigue resistance, and functional ability (stair climbing,…”
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Recombinant Human Bone Morphogenetic Protein-2 in Open Tibial Fractures: A Subgroup Analysis of Data Combined from Two Prospective Randomized Studies by Swiontkowski, Marc F, Aro, Hannu T, Donell, Simon, Esterhai, John L, Goulet, James, Jones, Alan, Kregor, Philip J, Nordsletten, Lars, Paiement, Guy, Patel, Amratlal

“…BackgroundThe use of recombinant human bone morphogenetic protein-2 (rhBMP-2) to improve the healing of open tibial shaft fractures has been the focus of two…”
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Compartment Syndrome in Tibial Fractures by Park, SangDo, Ahn, Jaimo, Gee, Albert O, Kuntz, Andrew F, Esterhai, John L

“…OBJECTIVES:Compartment syndrome is a devastating complication of tibial fractures. The purpose of this study was to investigate the rate of clinically…”
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Systematic Review of Cemented and Uncemented Hemiarthroplasty Outcomes for Femoral Neck Fractures by Ahn, Jaimo, Man, Li-Xing, Park, SangDo, Sodl, Jeffrey F., Esterhai, John L.

“…Although hemiarthroplasties are an important treatment for femoral neck fractures, the literature does not provide a clear approach for selecting the implant…”
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Delay in Surgical Débridement of Open Tibia Fractures: An Analysis of National Practice Trends by Namdari, Surena, Baldwin, Keith D, Matuszewski, Paul, Esterhai, John L, Mehta, Samir

“…BACKGROUND:Débridement and irrigation (D&I) of open tibia fractures less than 6 hours from the time of injury has been promoted as orthopaedic dogma despite…”
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Fabrication and evaluation of biomimetic-synthetic nanofibrous composites for soft tissue regeneration by Gee, Albert O, Baker, Brendon M, Silverstein, Amy M, Montero, Giana, Esterhai, John L, Mauck, Robert L

“…Electrospun scaffolds hold promise for the regeneration of dense connective tissues, given their nanoscale topographies, provision of directional cues for…”
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Antibiotic Treatment and Timing of Reimplantation by Restrepo, Camilo, Schmitt, Steven, Backstein, David, Alexander, Bryan T, Babic, Maja, Brause, Barry D, Esterhai, John L, Good, Robert P, Jørgensen, Peter H, Lee, Paul, Marculescu, Camelia, Mella, Claudio, Perka, Carsten, Eslam, Aidin, Rubash, Harry E, Saito, Tomoyuki, Suarez, Rolando, Townsend, Robert, Tözün, I Remzi, Van den Bekerom, Michel P J

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