Search Results - "Estepa, Gabriela"

Inhibiting stromal Class I HDACs curbs pancreatic cancer progression by Liang, Gaoyang, Oh, Tae Gyu, Hah, Nasun, Tiriac, Hervé, Shi, Yu, Truitt, Morgan L., Antal, Corina E., Atkins, Annette R., Li, Yuwenbin, Fraser, Cory, Ng, Serina, Pinto, Antonio F. M., Nelson, Dylan C., Estepa, Gabriela, Bashi, Senada, Banayo, Ester, Dai, Yang, Liddle, Christopher, Yu, Ruth T., Hunter, Tony, Engle, Dannielle D., Han, Haiyong, Von Hoff, Daniel D., Downes, Michael, Evans, Ronald M.

“…Oncogenic lesions in pancreatic ductal adenocarcinoma (PDAC) hijack the epigenetic machinery in stromal components to establish a desmoplastic and therapeutic…”
Get full text

Enhanced NF-κB Activation and Cellular Function in Macrophages Lacking IκB Kinase 1 (IKK1) by Li, Quitang, Lu, Qingxian, Bottero, Virginie, Estepa, Gabriela, Morrison, Lisa, Mercurio, Frank, Verma, Inder M.

“…IκB kinase (IKK) complex plays a key regulatory role in macrophages for NF-κB activation during both innate and adaptive immune responses. Because IKK1-/-mice…”
Get full text

Identification of 14-3-3σ Mutation Causing Cutaneous Abnormality in Repeated-Epilation Mutant Mouse by Li, Qiutang, Lu, Qingxian, Estepa, Gabriela, Verma, Inder M.

“…Repeated-epilation (Er) mutation in the mouse is inherited as an autosomal and semidominant mutation. Major defects in heterozygous adults and homozygous…”
Get full text

Vitamin D Switches BAF Complexes to Protect β Cells by Wei, Zong, Yoshihara, Eiji, He, Nanhai, Hah, Nasun, Fan, Weiwei, Pinto, Antonio F.M., Huddy, Timothy, Wang, Yuhao, Ross, Brittany, Estepa, Gabriela, Dai, Yang, Ding, Ning, Sherman, Mara H., Fang, Sungsoon, Zhao, Xuan, Liddle, Christopher, Atkins, Annette R., Yu, Ruth T., Downes, Michael, Evans, Ronald M.

“…A primary cause of disease progression in type 2 diabetes (T2D) is β cell dysfunction due to inflammatory stress and insulin resistance. However, preventing…”
Get full text

Reduced IGF-1 Signaling Delays Age-Associated Proteotoxicity in Mice by Cohen, Ehud, Paulsson, Johan F., Blinder, Pablo, Burstyn-Cohen, Tal, Du, Deguo, Estepa, Gabriela, Adame, Anthony, Pham, Hang M., Holzenberger, Martin, Kelly, Jeffery W., Masliah, Eliezer, Dillin, Andrew

“…The insulin/insulin growth factor (IGF) signaling (IIS) pathway is a key regulator of aging of worms, flies, mice, and likely humans. Delayed aging by IIS…”
Get full text

Bromodomain containing 9 (BRD9) regulates macrophage inflammatory responses by potentiating glucocorticoid receptor activity by Wang, Liu, Oh, Tae Gyu, Magida, Jason, Estepa, Gabriela, Obayomi, S. M. Bukola, Chong, Ling-Wa, Gatchalian, Jovylyn, Yu, Ruth T., Atkins, Annette R., Hargreaves, Diana, Downes, Michael, Wei, Zong, Evans, Ronald M.

“…In macrophages, homeostatic and immune signals induce distinct sets of transcriptional responses, defining cellular identity and functional states. The…”
Get full text

A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer by Antal, Corina E., Oh, Tae Gyu, Aigner, Stefan, Luo, En-Ching, Yee, Brian A., Campos, Tania, Tiriac, Hervé, Rothamel, Katherine L., Cheng, Zhang, Jiao, Henry, Wang, Allen, Hah, Nasun, Lenkiewicz, Elizabeth, Lumibao, Jan C., Truitt, Morgan L., Estepa, Gabriela, Banayo, Ester, Bashi, Senada, Esparza, Edgar, Munoz, Ruben M., Diedrich, Jolene K., Sodir, Nicole M., Mueller, Jasmine R., Fraser, Cory R., Borazanci, Erkut, Propper, David, Von Hoff, Daniel D., Liddle, Christopher, Yu, Ruth T., Atkins, Annette R., Han, Haiyong, Lowy, Andrew M., Barrett, Michael T., Engle, Dannielle D., Evan, Gerard I., Yeo, Gene W., Downes, Michael, Evans, Ronald M.

“…Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy in need of new therapeutic options. Using unbiased analyses of super-enhancers (SEs) as…”
Get full text

Complete lack of NF-κB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation by Li, Qiutang, Estepa, Gabriela, Memet, Sylvie, Israel, Alain, Verma, Inder M.

“…NF-κB activity is induced by cytokines, stress, and pathogens. IKK1 and IKK2 are critical IκB kinases in NF-κB activation. In this study mice lacking IKK1 and…”
Get full text

Reduced IGF-1 Signaling Delays Age-Associated Proteotoxicity in Mice by Cohen, Ehud, Paulsson, Johan F., Blinder, Pablo, Burstyn-Cohen, Tal, Du, Deguo, Estepa, Gabriela, Adame, Anthony, Pham, Hang M., Holzenberger, Martin, Kelly, Jeffery W., Masliah, Eliezer, Dillin, Andrew

Get full text

Identification of 14-3-3sigma mutation causing cutaneous abnormality in repeated-epilation mutant mouse by Li, Qiutang, Lu, Qingxian, Estepa, Gabriela, Verma, Inder M

“…Repeated-epilation (Er) mutation in the mouse is inherited as an autosomal and semidominant mutation. Major defects in heterozygous adults and homozygous…”
Get full text

Enhanced NF-kappaB activation and cellular function in macrophages lacking I{kappa}B kinase 1 (IKK1) by Li, Qiutang, Lu, Qingxian, Bottero, Virginie, Estepa, Gabriela

“…I[kappa]B[alpha] kinase (IKK) complex plays a key regulatory role in macrophages for NF-[kappa]B activation during both innate and adaptive immune responses…”
Get full text

Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1) by Li, Qiutang, Lu, Qingxian, Bottero, Virginie, Estepa, Gabriela, Morrison, Lisa, Mercurio, Frank, Verma, Inder M

“…IkappaB kinase (IKK) complex plays a key regulatory role in macrophages for NF-kappaB activation during both innate and adaptive immune responses. Because…”
Get full text

Cloning and nucleotide sequence of a flagellin-coding gene (hag) from Serratia marcescens 274 by Harshey, R M, Estepa, G, Yanagi, H

“…The pigmented enterobacterium Serratia marcescens shows a high frequency of color variation. In strain 274, color variation was shown to be closely associated…”
Get more information